Catalog No.
YHG49401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala978-Asn1099
Predicted molecular weight
16.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13349
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Leukointegrin alpha D, Integrin alpha-D, CD11d, CD11 antigen-like family member D, ITGAD, ADB2
Multifaceted, unique role of CD11c in leukocyte biology., PMID:40103815
Determining Ligand Binding and Specificity Within the β2-Integrin Family with a Novel Assay Platform., PMID:40001541
The influence of Salvia cadmica Boiss. extracts on the M1/M2 polarization of macrophages primed with Helicobacter pylori lipopolysaccharide in conjunction with NF-kappa B activation, production of cytokines, phagocytic activity and total DNA methylation., PMID:36921911
Mycobacterium bovis BCG increase the selected determinants of monocyte/macrophage activity, which were diminished in response to gastric pathogen Helicobacter pylori., PMID:36813949
αDβ2 as a novel target of experimental polymicrobial sepsis., PMID:36466931
Modification of Extracellular Matrix by the Product of DHA Oxidation Switches Macrophage Adhesion Patterns and Promotes Retention of Macrophages During Chronic Inflammation., PMID:35720381
LINC02190 inhibits the embryo-endometrial attachment by decreasing ITGAD expression., PMID:35038314
β2 Integrin CD11d/CD18: From Expression to an Emerging Role in Staged Leukocyte Migration., PMID:34858434
Case report: Haemophagocytic histiocytic sarcoma in an english setter., PMID:33750030
A resolving role for neutrophil CD11d in facilitating neutrophil survival and macrophage efferocytosis during sepsis?, PMID:33527505
Frontline Science: The expression of integrin αD β2 (CD11d/CD18) on neutrophils orchestrates the defense mechanism against endotoxemia and sepsis., PMID:33438263
Human Liver Macrophage Subsets Defined by CD32., PMID:33101269
CD11d is a novel antigen on chicken leukocytes., PMID:32534212
Docetaxel Upregulates HMGB1 Levels in Non-small Cell Lung Cancer., PMID:32115500
β2 Integrins-Multi-Functional Leukocyte Receptors in Health and Disease., PMID:32092981
Integrin αDβ2 influences cerebral edema, leukocyte accumulation and neurologic outcomes in experimental severe malaria., PMID:31869339
Characterisation of a New Human Alveolar Macrophage-Like Cell Line (Daisy)., PMID:31732808
CD11b Regulates Fungal Outgrowth but Not Neutrophil Recruitment in a Mouse Model of Invasive Pulmonary Aspergillosis., PMID:30778357
Distinct Migratory Properties of M1, M2, and Resident Macrophages Are Regulated by αDβ2 and αMβ2 Integrin-Mediated Adhesion., PMID:30524429
Integrin αDβ2 (CD11d/CD18) Modulates Leukocyte Accumulation, Pathogen Clearance, and Pyroptosis in Experimental Salmonella Typhimurium Infection., PMID:29881383
Identification of Proteomic Features To Distinguish Benign Pulmonary Nodules from Lung Adenocarcinoma., PMID:28731711
The effectiveness of the anti-CD11d treatment is reduced in rat models of spinal cord injury that produce significant levels of intraspinal hemorrhage., PMID:28587875
The Upregulation of Integrin αDβ2 (CD11d/CD18) on Inflammatory Macrophages Promotes Macrophage Retention in Vascular Lesions and Development of Atherosclerosis., PMID:28500072
CD11d β2 integrin expression on human NK, B, and γδ T cells., PMID:27881604
Integrin αDβ2 (CD11d/CD18) mediates experimental malaria-associated acute respiratory distress syndrome (MA-ARDS)., PMID:27473068
The Role of Integrins αMβ2 (Mac-1, CD11b/CD18) and αDβ2 (CD11d/CD18) in Macrophage Fusion., PMID:27315778
Cutaneous histiocytic sarcoma with E-cadherin expression in a Pembroke Welsh Corgi dog., PMID:26330395
CD11d integrin blockade reduces the systemic inflammatory response syndrome after traumatic brain injury in rats., PMID:26169930
Integrin αDβ2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling., PMID:25415295
Resistant starch improves insulin resistance and reduces adipose tissue weight and CD11c expression in rat OLETF adipose tissue., PMID:24698351
Ex vivo expansion of canine cytotoxic large granular lymphocytes exhibiting characteristics of natural killer cells., PMID:23548866
Immunohistochemical evaluation of the effects of paraffin section storage on biomarker stability., PMID:23435571
Treatment with an anti-CD11d integrin antibody reduces neuroinflammation and improves outcome in a rat model of repeated concussion., PMID:23414334
The class A macrophage scavenger receptor CD204 is a useful immunohistochemical marker of canine histiocytic sarcoma., PMID:22901707
Hepatosplenic and hepatocytotropic T-cell lymphoma: two distinct types of T-cell lymphoma in dogs., PMID:22711745
A CD11d monoclonal antibody treatment reduces tissue injury and improves neurological outcome after fluid percussion brain injury in rats., PMID:22676851
Genetic influences on craving for alcohol., PMID:22481050
The systemic inflammatory response after spinal cord injury in the rat is decreased by α4β1 integrin blockade., PMID:22150233
Anti-CD11d monoclonal antibody treatment for rat spinal cord compression injury., PMID:22078757
CD11d Antibody Treatment Improves Recovery in Spinal Cord-Injured Mice., PMID:22044160
Characterization of immune cell infiltration into canine intracranial meningiomas., PMID:21987303
CD11d integrin blockade reduces the systemic inflammatory response syndrome after spinal cord injury., PMID:21784069
On the potential involvement of CD11d in co-stimulating the production of interferon-γ by natural killer cells upon interaction with neutrophils via intercellular adhesion molecule-3., PMID:21712539
Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obese rodents and women., PMID:21508205
Anti-CD11d monoclonal antibody treatment for rat spinal cord compression injury., PMID:21145887
Human spinal cord injury causes specific increases in surface expression of β integrins on leukocytes., PMID:21142687
Establishment and characterization of a novel canine B-cell line derived from a spontaneously occurring diffuse large cell lymphoma., PMID:20153049
A systematic review of directly applied biologic therapies for acute spinal cord injury., PMID:20082560
Mary Allen Engle Award: The glue of life--a career retrospective., PMID:21686217
beta2-integrins in demyelinating disease: not adhering to the paradigm., PMID:20007244
For research use only. Not for human or drug use.
