Catalog No.
YHG31401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg89-Ala406
Predicted molecular weight
38.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q12864
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CDH17, Intestinal peptide-associated transporter HPT-1, LI-cadherin, Liver-intestine cadherin, Cadherin-17
CDH17-targeting CAR-NK cells synergize with CD47 blockade for potent suppression of gastrointestinal cancers., PMID:40487639
Systemic delivery of cadherin 17-specific CAR T cells allows effective and safe targeting of colorectal cancer liver metastases., PMID:40435215
Nanobody Engineered and Photosensitiser Loaded Bacterial Outer Membrane Vesicles Potentiate Antitumour Immunity and Immunotherapy., PMID:40240911
Development and Characterization of the [177Lu]Lu-Labeled Anti-CDH17 Nanobody Derivative for Radioimmunotherapy in the Gastric Cancer Xenograft Model., PMID:40088168
Regulating chemoresistance and cancer stemness: the CDH17-YAP pathway in distinct cellular states of lung cancer CTC clusters., PMID:39994505
Integration of Gastric Cancer RNA-Seq Datasets Along With PPI Network Suggests That Nonhub Nodes Have the Potential to Become Biomarkers., PMID:39854135
A bispecific antibody-drug conjugate targeting pCAD and CDH17 has antitumor activity and improved tumor-specificity., PMID:39762718
Tissue Cadherin 17 (CDH17): An Important Prognostic Determinant of Colorectal Cancer Using Digital Image Analysis., PMID:39617741
Identification of key genes and pathways involved in T-DM1-resistance in OE-19 esophageal cancer cells through bioinformatics analysis., PMID:39309859
Expression profiles of cadherin 17 and claudin 18.2 in comparison with peptide hormonal expression in pancreatic neuroendocrine tumours: Implications for targeted immunotherapy., PMID:39178509
Variability in morphology and immunohistochemistry of Crohn's disease-associated small bowel neoplasms: implications of Claudin 18 and Cadherin 17 expression for tumor-targeted immunotherapies., PMID:39164422
Cadherin 17 Nanobody-Mediated Near-Infrared-II Fluorescence Imaging-Guided Surgery and Immunotoxin Delivery for Colorectal Cancer., PMID:38911825
Nanobody-Engineered Biohybrid Bacteria Targeting Gastrointestinal Cancers Induce Robust STING-Mediated Anti-Tumor Immunity., PMID:38888519
Comprehensive landscape of junctional genes and their association with overall survival of patients with lung adenocarcinoma., PMID:38841188
Cadherin-17 as a target for the immunoPET of adenocarcinoma., PMID:38625402
Proteomics-Derived Biomarker Panel Facilitates Distinguishing Primary Lung Adenocarcinomas With Intestinal or Mucinous Differentiation From Lung Metastatic Colorectal Cancer., PMID:38608841
Cadherin-17 (CDH17) expression in human cancer: A tissue microarray study on 18,131 tumors., PMID:38452580
A complex of cadherin 17 with desmocollin 1 and p120-catenin regulates colorectal cancer migration and invasion according to the cell phenotype., PMID:38263178
Primary mucinous adenocarcinoma of the urethra: A clinicopathological analysis of 35 cases., PMID:38114291
Targeting CDH17 with Chimeric Antigen Receptor-Redirected T Cells in Small Cell Lung Cancer., PMID:37823901
A multi-mineral intervention to counter pro-inflammatory activity and to improve the barrier in human colon organoids., PMID:37476158
Diagnostic gastrointestinal markers in primary lung cancer and pulmonary metastases., PMID:37349623
Integrated transcriptomics and proteomics data analysis identifies CDH17 as a key cell surface target in colorectal cancer., PMID:37247573
Molecular mechanism underlying the increased risk of colorectal cancer metastasis caused by single nucleotide polymorphisms in LI-cadherin gene., PMID:37081068
Machine learning-based immune prognostic model and ceRNA network construction for lung adenocarcinoma., PMID:36939925
SEPT9 Expression in Hepatic Nodules: An Immunohistochemical Study of Hepatocellular Neoplasm and Metastasis., PMID:36867734
The diagnostic significance of CDH17-positive circulating tumor cells in patients with colorectal cancer., PMID:36744385
Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide Association Studies and Transcriptome-Wide Association Study., PMID:36672800
CDH17 nanobodies facilitate rapid imaging of gastric cancer and efficient delivery of immunotoxin., PMID:36435809
Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis., PMID:36152751
A proximity labeling method for protein-protein interactions on cell membrane., PMID:35685794
Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues., PMID:35314826
Expression Profile and Prognostic Values of CDH Family Members in Lung Adenocarcinoma., PMID:35242247
The Relationship between Cadherin Polymorphisms and the Risk of Delayed Encephalopathy after Acute Carbon Monoxide Poisoning in the Chinese Han Population., PMID:35140817
Identification of miRNAs and genes for predicting Barrett's esophagus progressing to esophageal adenocarcinoma using miRNA-mRNA integrated analysis., PMID:34818353
Clinicopathological and prognostic significance of immunophenotypic characterization of endocervical adenocarcinoma using CLDN18, CDH17, and PAX8 in association with HPV status., PMID:34581850
Mechanism of dimerization and structural features of human LI-cadherin., PMID:34364873
Aberrant expression of SATB2, CDX2, CDH17 and CK20 in hepatocellular carcinoma: a pathological, clinical and outcome study., PMID:34036629
CDH17+/CDX2+ Can be Helpful in Providing Support for Small Intestinal Origin Versus Pancreatic or Biliary Origin., PMID:33958523
Exploration of zebrafish larvae as an alternative whole-animal model for nephrotoxicity testing., PMID:33722575
CDH6-activated αIIbβ3 crosstalks with α2β1 to trigger cellular adhesion and invasion in metastatic ovarian and renal cancers., PMID:33715292
Crystal structure of the nonclassical cadherin-17 N-terminus and implications for its adhesive binding mechanism., PMID:33682793
Clinical correlation of cadherin-17 marker with advanced tumor stages and poor prognosis of cholangiocarcinoma., PMID:33524213
Selective Tumor Cell Apoptosis and Tumor Regression in CDH17-Positive Colorectal Cancer Models using BI 905711, a Novel Liver-Sparing TRAILR2 Agonist., PMID:33037135
Immunoaffinity enrichment LC-MS/MS quantitation of CDH17 in tissues., PMID:33006478
Cadherin-17 Targeted Near-Infrared Photoimmunotherapy for Treatment of Gastrointestinal Cancer., PMID:32931292
The Diagnostic Value of Cadherin 17 and CDX2 Expression as Immunohistochemical Markers in Colorectal Adenocarcinoma., PMID:32929682
Quantifying drug tissue biodistribution by integrating high content screening with deep-learning analysis., PMID:32873881
64Cu-labeled minibody D2101 visualizes CDH17-positive gastric cancer xenografts with short waiting time., PMID:32371673
A panel of intestinal differentiation markers (CDX2, GPA33, and LI-cadherin) identifies gastric cancer patients with favourable prognosis., PMID:32215766
For research use only. Not for human or drug use.
