Catalog No.
YHG28501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser301-Gly655
Predicted molecular weight
40.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q12778
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Forkhead box protein O1, FKHR, FOXO1A, Forkhead in rhabdomyosarcoma, Forkhead box protein O1A, FOXO1
SIRT1 Regulates Iron Metabolism to Attenuate β-Cell Dedifferentiation by Inhibiting FoxO1 Acetylation., PMID:40512369
Identification and validation of cellular senescence-related genes and immune cell infiltration characteristics in intervertebral disc degeneration., PMID:40510349
A Study on the Differences in Rumen Microbiota-Liver Gluconeogenesis-Mitochondrial Interaction Between Tibetan Sheep and Hu Sheep in the Qinghai-Tibet Plateau., PMID:40509071
FOXO1 contributes to cigarette smoke condensate-induced cellular senescence and fibrosis in lung fibroblasts through activating the TGF-β1/Smad2/3 signaling pathway., PMID:40498253
Regulation of carcinogenesis through multiple zinc fingers in ZBTB20., PMID:40497236
Endoplasmic reticulum stress and forkhead box protein O1 inhibition mediate palmitic acid and high glucose-induced β-cell dedifferentiation., PMID:40487627
GHSR-Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation., PMID:40479577
Fusion transcription factor dosage controls cell state in rhabdomyosarcoma., PMID:40475567
NPB-1575 attenuates neuroinflammation and resists ferroptosis in rat ischemic stroke via IRS2 signaling pathway., PMID:40473822
CHIP mediates glucagon action on hepatic glucose production via regulating Smad3 ubiquitination., PMID:40462730
Denticleless homolog-mediated ubiquitin-proteasome degradation of forkhead box O1 contributes to development of carboplatin resistance in retinoblastoma., PMID:40455648
HDAC4: an emerging target in diabetes mellitus and diabetic complications., PMID:40448151
miR-486-5p Inhibits eNOS and Angiogenesis in Cultured Endothelial Cells by Targeting MAML3., PMID:40432288
The Role of Klotho in Oral and Maxillofacial Diseases: Mechanisms and Research Progress., PMID:40427517
Upregulation of SIRT1 ameliorates apoptosis of rat nucleus pulposus cells under oxidative stress through FoxO1/β-catenin pathway., PMID:40421819
Enhanced FOXO1 expression as a predictor of decitabine response and prolonged survival in high-risk myelodysplastic syndrome., PMID:40420801
Mangiferin mitigates dexamethasone-induced insulin resistance in rats: insight into vascular dysfunction and hepatic steatosis., PMID:40406487
NNMT/1-MNA protects against hepatic ischemia-reperfusion injury through the AKT/FOXO1/ANGPT2/JNK axis., PMID:40404636
MicroRNA-196a increases apoptosis in B cells through downregulation of FOXO1., PMID:40403879
Multi-organ transcriptomics provide insights into growth regulation in the Dongtingking crucian carp (Carassius auratus indigentiaus)., PMID:40398212
Pan-cancer analysis of phagocytosis regulators in female-specific cancers: a focus on HMGB2., PMID:40396172
Highly quantitative measurement of differential protein-genome binding with PerCell chromatin sequencing., PMID:40393455
YTHDF1 activates FBW7 transcription by regulating m6A-dependent FOXO1 to facilitate inflammatory response in ulcerative colitis-like model., PMID:40384634
High-salt-driven gut microbiota dysfunction aggravates prostatitis by promoting AHR/SGK1/FOXO1 axis-mediated Th17 cell differentiation., PMID:40383790
The interplay between FOXO1 and glucocorticoid signaling in promoting the terminal differentiation of somatotropes., PMID:40381980
Maternal high-fat diet exposure impairs LKB1-TGFβ1 inflammatory pathway and increases hypothalamic 5HT receptors gene expression and somatic growth in young rats., PMID:40381902
IFN-γ-mediated suppression of ANGPT2-Tie2 in endothelial cells facilitates tumor vascular normalization during immunotherapy., PMID:40370455
Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway., PMID:40365319
Bisphenol a Disrupts Steroidogenesis and Induces Apoptosis in Human Granulosa Cells Cultured In Vitro., PMID:40362320
Cold atmospheric plasma targets triple negative breast cancer cells via SCAF11-mediated competitive protein degradation and synergizes with miRNA-146b-5p., PMID:40360112
FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes., PMID:40357580
Ginsenoside Rk1 Ameliorates Non-Alcoholic Fatty Liver Disease by Targeting CD36 to Modulate the AMPK Signaling Pathway., PMID:40356178
Type I BODITh Photosensitizers with Twisted Conformation for Augmented Photodynamic Therapy and FOXO1-Involved Apoptosis., PMID:40353368
In vitro and in-vivo exploration of physostigmine analogues to understand the mechanistic crosstalk between Klotho and targets for epilepsy., PMID:40351444
lncRNA AK159072 Promotes Myoblast Proliferation and Muscle Regeneration Through Activation of Akt/Foxo1 Pathway., PMID:40341721
Human menstrual blood-derived stem cells secreted ECM1 directly interacts with LRP1α to ameliorate hepatic fibrosis through FoxO1 and mTOR signaling pathway., PMID:40336034
Multi-therapeutic strategy targeting Akt-mTOR and FoxO1 pathway to counteract skeletal muscle atrophy consecutive to hypoxia., PMID:40327324
Tie-2 regulates endothelial morphological responses to shear stress by FOXO1-triggered autophagy., PMID:40323944
Astragalus polysaccharides inhibits tumor proliferation and enhances cisplatin sensitivity in bladder cancer by regulating the PI3K/AKT/FoxO1 axis., PMID:40318719
Associations between FOXO1 expression in tissue, the pathological characteristics of colorectal cancer, and patient survival., PMID:40314832
Downregulation of Akt induces proximal tubule epithelial cell apoptosis via Foxo-1-BIM pathway in proteinuric states., PMID:40313745
α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT-FOXO1-CD36 pathway., PMID:40313619
Activation of central Angiotensin-(1-7)/Mas receptor alleviates synaptic damage in diabetes-associated cognitive impairment via modulating AKT/FOXO1/PACAP axis., PMID:40303297
The role of macrophages in polycystic ovary syndrome: A review., PMID:40295243
Knockdown of circRNA_0030042 Attenuates Heart Failure via miR-568/PRG4 Pathway., PMID:40293855
DYRK1B phosphorylates FOXO1 to promote hepatic gluconeogenesis., PMID:40287828
A Potential Link Between Early Onset Reactive Astrogliosis and Adult-Onset Dysfunction of Leptin Signaling in Polyubiquitin Gene Ubb Knockout Mice., PMID:40287809
Establishment and Characterization of Hepatocyte Line from Turbot (Scophthalmus maximus L.) and Its Application in the Study of Glucose Metabolism., PMID:40272575
FOXO1 mediates miR-99a-5p/E2F7 to restrain breast cancer cell proliferation and induce apoptosis., PMID:40264026
Remimazolam alleviates hepatic ischemia-reperfusion injury by activating FOXO1/3 signaling : Remimazolam alleviates hepatic ischemia reperfusion injury., PMID:40263992
For research use only. Not for human or drug use.
