Catalog No.
YHG27701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Lys414
Predicted molecular weight
48.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q12765
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA0193, SCRN1, Secernin-1
Genetic correlation, shared loci, but no causality between bipolar disorder and inflammatory bowel disease: A genome-wide pleiotropic analysis., PMID:38154582
Knockdown of Secernin 1 inhibit cell invasion and migration by activating the TGF-β/Smad3 pathway in oral squamous cell carcinomas., PMID:37691034
Exploratory Assessment of Proteomic Network Changes in Cerebrospinal Fluid of Mild Cognitive Impairment Patients: A Pilot Study., PMID:37509130
SCRN1: A cerebrospinal fluid biomarker correlating with tau in Alzheimer's disease., PMID:36946611
The Sertoli cell expressed gene secernin-1 (Scrn1) is dispensable for male fertility in the mouse., PMID:33442887
Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer's disease and not in other tauopathies., PMID:31796108
VAP-SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function., PMID:31441084
Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation., PMID:26883194
OCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates., PMID:26510499
Proteomic analysis of fetal programming-related obesity markers., PMID:25886259
Secernin-1 contributes to colon cancer progression through enhancing matrix metalloproteinase-2/9 exocytosis., PMID:25814779
Identification and validation of potential new biomarkers for prostate cancer diagnosis and prognosis using 2D-DIGE and MS., PMID:25667921
A genetic variant of miR-148a binding site in the SCRN1 3'-UTR is associated with susceptibility and prognosis of gastric cancer., PMID:25399950
Concurrent gene signatures for han chinese breast cancers., PMID:24098497
Identification of genes specifically methylated in Epstein-Barr virus-associated gastric carcinomas., PMID:23829175
Proteomic profiling of brain cortex tissues in a Tau transgenic mouse model of Alzheimer's disease., PMID:23211594
Secernin-1 as a novel prognostic biomarker candidate of synovial sarcoma revealed by proteomics., PMID:21385630
Digital transcript profile analysis with aRNA-LongSAGE validates FERMT1 as a potential novel prognostic marker for colon cancer., PMID:21220475
SCRN1: a biomarker for colorectal cancer?, PMID:20461775
SCRN1 is a novel marker for prognosis in colorectal cancer., PMID:20039278
New candidate genes identified for controlling mouse gonadal sex determination and the early stages of granulosa and Sertoli cell differentiation., PMID:19864314
Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray., PMID:16630140
Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray., PMID:16367923
Purification and identification of secernin, a novel cytosolic protein that regulates exocytosis in mast cells., PMID:12221138
For research use only. Not for human or drug use.
