Catalog No.
YHG17801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg835-Asn1061
Predicted molecular weight
27.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q08828
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ca(2+)/calmodulin-activated adenylyl cyclase, ADCY1, Adenylate cyclase type 1, Adenylyl cyclase 1, ATP pyrophosphate-lyase 1, Adenylate cyclase type I
The ADCY1-mediated cAMP signaling pathway mediates functional effects of montelukast treatment in brain organoids., PMID:40471331
Ginsenoside Rg1 alleviates cognitive impairment in vascular dementia by modulating Adcy1/Kdr-mediated cholinergic synapse and PI3K-AKT pathway., PMID:40424986
Fuling Wenxin formula treats "Qi-Yin deficiency" arrhythmia by regulating the dilated cardiomyopathy and adrenergic signaling pathway in cardiomyocytes., PMID:40319835
Serum-Based Proteomic Approach to Identify Clinical Biomarkers of Radiation Exposure., PMID:40149344
Genome-wide identification of FTZ-F1 genes in Chlamys farreri and analysis of ChIP-seq-based binding sites and potential target genes., PMID:40068440
Epigenetic modulation rescues neurodevelopmental deficits in Syngap1+/- mice., PMID:39878322
Inulin may prevent the high-fat diet induced-obesity via suppressing endocannabinoid system in the prefrontal cortex in Wistar rats., PMID:39363521
Neuronal LAMP2A-mediated reduction of adenylyl cyclases induces acute neurodegenerative responses and neuroinflammation after ischemic stroke., PMID:39341961
Adenylate cyclase 1 knockdown attenuates pirarubicin-induced cardiotoxicity., PMID:39227014
Differentially expressed genes associated with high metabolic tumor volume served as diagnostic markers and potential therapeutic targets for pancreatic cancer., PMID:38741142
Regulation of cardiac fibrosis in mice with TAC/DOCA-induced HFpEF by resistin-like molecule gamma and adenylate cyclase 1., PMID:38710658
Elevated PDE4C level serves as a candidate diagnostic biomarker and correlates with poor survival in thyroid carcinoma., PMID:38514754
Soluble adenylyl cyclase, the cell-autonomous member of the family., PMID:37951509
Illuminating (HTLV-1)-induced adult T-cell leukemia/lymphoma transcriptomic signature: A systems virology approach., PMID:37832654
Opposite regulation of glycogen metabolism by cAMP produced in the cytosol and at the plasma membrane., PMID:37714306
Downregulated INHBB in endometrial tissue of recurrent implantation failure patients impeded decidualization through the ADCY1/cAMP signalling pathway., PMID:36913138
CUX2 prevents the malignant progression of gliomas by enhancing ADCY1 transcription., PMID:36242624
Strategies to safely target widely expressed soluble adenylyl cyclase for contraception., PMID:36091839
Electroacupuncture Alleviates Thalamic Pain in Rats by Suppressing ADCY1 Protein Upregulation., PMID:35793187
LncRNA H19 acts as miR-301a-3p sponge to alleviate lung injury in mice with sepsis by regulating Adcy1., PMID:35438054
Expression and functions of adenylyl cyclases in the CNS., PMID:35307032
Circ-LTBP1 is involved in doxorubicin-induced intracellular toxicity in cardiomyocytes via miR-107/ADCY1 signal., PMID:35076816
GNG7 and ADCY1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma through bioinformatic-based analyses., PMID:34650124
Pancreatic cancer-derived exosomal microRNA-19a induces β-cell dysfunction by targeting ADCY1 and EPAC2., PMID:34512170
Screening of tumor grade-related mRNAs and lncRNAs for Esophagus Squamous Cell Carcinoma., PMID:33960436
Long non-coding RNA DPP10-AS1 exerts anti-tumor effects on colon cancer via the upregulation of ADCY1 by regulating microRNA-127-3p., PMID:33744851
Genetic analyses of the endocannabinoid pathway in association with affective phenotypic variants., PMID:33421489
Circular RNA Arhgap12 modulates doxorubicin-induced cardiotoxicity by sponging miR-135a-5p., PMID:33245966
Histone deacetylase inhibition by MS-275 potentiates glucose-stimulated insulin secretion without affecting glucose oxidation., PMID:32663574
Asiaticoside might attenuate bleomycin-induced pulmonary fibrosis by activating cAMP and Rap1 signalling pathway assisted by A2AR., PMID:32548952
Identification of biomarkers of clear cell renal cell carcinoma by bioinformatics analysis., PMID:32481352
A perspective profile of ADCY1 in cAMP signaling with drug-resistance in lung cancer., PMID:31839819
The roles of Qishen granules recipes, Qingre Jiedu, Wenyang Yiqi and Huo Xue, in the treatment of heart failure., PMID:31683036
T5224, RSPO2 and AZD5363 are novel drugs against functional pituitary adenoma., PMID:31655798
L1 Cell Adhesion Molecule Overexpression Down Regulates Phosphacan and Up Regulates Structural Plasticity-Related Genes Rostral and Caudal to the Complete Spinal Cord Transection., PMID:31426714
Cell Death Induced by Cationic Amphiphilic Drugs Depends on Lysosomal Ca2+ Release and Cyclic AMP., PMID:31285280
Identification of key candidate genes involved in melanoma metastasis., PMID:31173190
Dihydromyricetin ameliorates memory impairment induced by acute sleep deprivation., PMID:30876981
MicroRNA-23a-3p Inhibits Mucosal Melanoma Growth and Progression through Targeting Adenylate Cyclase 1 and Attenuating cAMP and MAPK Pathways., PMID:30867808
High-fat diet impacts more changes in beta-cell compared to alpha-cell transcriptome., PMID:30849121
Candidate gene and pathway analyses identifying genetic variations associated with prasugrel pharmacokinetics and pharmacodynamics., PMID:30458339
[Study on relevance mining of "core drug action target" in Dictionary of Traditional Chinese Medicine Prescriptions]., PMID:30453719
Ontogeny-related pharmacogene changes in the pediatric liver transcriptome., PMID:29360682
Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1., PMID:29331508
Common functional variants of the glutamatergic system in Autism spectrum disorder with high and low intellectual abilities., PMID:29147782
Suxiao Jiuxin Pill protects cardiomyocytes against mitochondrial injury and alters gene expression during ischemic injury., PMID:29042943
Functional analysis of schizophrenia genes using GeneAnalytics program and integrated databases., PMID:29032150
Identification of a myofibroblast-specific expression signature in skin wounds., PMID:28797711
Laurus nobilis: Composition of Essential Oil and Its Biological Activities., PMID:28587201
Enhanced expression of ADCY1 underlies aberrant neuronal signalling and behaviour in a syndromic autism model., PMID:28218269
For research use only. Not for human or drug use.
