Catalog No.
YHG17101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala486-Asn686
Predicted molecular weight
25.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q08554
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DSC1, Desmosomal glycoprotein 2/3, Desmocollin-1, DG2/DG3, Cadherin family member 1, CDHF1
Discovery of new protein partners of anterior gradient 2 (AGR2) from cell-cell adhesion pathway using genetically-encoded photo-crosslinker DiZPK., PMID:40367911
Effect of heat stress on ileal epithelial barrier integrity in broilers divergently selected for high- and low-water efficiency., PMID:40260206
Low-Dose Docetaxel Is Effective in Reducing Atherogenic Lipids and Atherosclerosis., PMID:40003949
Lipidomic and Proteomic Insights from Extracellular Vesicles in Postmortem Dorsolateral Prefrontal Cortex Reveal Substance Use Disorder-Induced Brain Changes., PMID:39211229
Combining sandblasting and pink anodisation of Ti implants as a promising method for improving fibroblast adhesion and immune response., PMID:39141321
Immunohistopathological analyses of a case of pemphigus vegetans with antibodies against desmoglein 1 and desmocollins 1-3., PMID:39073162
Temporal Assessment of Protein Stability in Dried Blood Spots., PMID:38950347
Re-evaluating the prevalence of anti-desmocollin-1 IgA autoantibodies in canine pemphigus foliaceus., PMID:38820947
ARF6 promotes Streptococcus suis suilysin induced apoptosis in HBMECs., PMID:38663699
Honeybee CaV4 has distinct permeation, inactivation, and pharmacology from homologous NaV channels., PMID:38557788
Critical importance of DNA binding for CSL protein functions in fission yeast., PMID:38482739
A complex of cadherin 17 with desmocollin 1 and p120-catenin regulates colorectal cancer migration and invasion according to the cell phenotype., PMID:38263178
Pemphigus Autoantibodies to Desmocollin 3 but Not to Desmocollin 1 Directly Block Heterophilic Desmoglein/Desmocollin Transinteraction., PMID:38101510
Canine Somatic Mutations from Whole-Exome Sequencing of B-Cell Lymphomas in Six Canine Breeds-A Preliminary Study., PMID:37760246
Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide., PMID:37620794
Docetaxel as a Model Compound to Promote HDL (High-Density Lipoprotein) Biogenesis and Reduce Atherosclerosis., PMID:36861478
Role of DSC1 in Drosophila melanogaster synaptic activities in response to haedoxan A., PMID:36752392
Significance of anti-desmocollin autoantibodies in pemphigus., PMID:36578135
Subcorneal pustular dermatosis-type IgA pemphigus associated with multiple myeloma: A case report and literature review., PMID:35838241
Trunk-dominant and classic facial pemphigus foliaceus in dogs - comparison of anti-desmocollin-1 and anti-desmoglein-1 autoantibodies and clinical presentations., PMID:35670648
Collective mechanical responses of cadherin-based adhesive junctions as predicted by simulations., PMID:35150618
SWI/SNF and RSC remodeler complexes bind to MBF-dependent genes., PMID:34843421
Gene expression profiling of laminin α3-blocked keratinocytes reveals an immune-independent mechanism of blistering., PMID:34796550
Uniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis., PMID:34454985
Identification of Docetaxel as a Potential Drug to Promote HDL Biogenesis., PMID:34093205
Derma-Hc, a New Developed Herbal Formula, Ameliorates Cutaneous Lichenification in Atopic Dermatitis., PMID:33652999
CircRAB11FIP1 promoted autophagy flux of ovarian cancer through DSC1 and miR-129., PMID:33637694
The Transcription Factor p63 Is a Direct Effector of IL-4- and IL-13-Mediated Repression of Keratinocyte Differentiation., PMID:33038352
Open trial of Bruton's tyrosine kinase inhibitor (PRN1008) in the treatment of canine pemphigus foliaceus., PMID:32803903
Skin characteristics associated with foot callus in people with diabetes: A cross-sectional study focused on desmocollin1 in corneocytes., PMID:32653294
Pemphigus Vulgaris and Foliaceus IgG Autoantibodies Directly Block Heterophilic Transinteraction between Desmoglein and Desmocollin., PMID:32142800
The TIR-NB-LRR pair DSC1 and WRKY19 contributes to basal immunity of Arabidopsis to the root-knot nematode Meloidogyne incognita., PMID:32054439
Igalan from Inula helenium (L.) suppresses the atopic dermatitis-like response in stimulated HaCaT keratinocytes via JAK/STAT3 signaling., PMID:32002586
Efficacy of a Bruton's Tyrosine Kinase Inhibitor (PRN-473) in the treatment of canine pemphigus foliaceus., PMID:31899567
The role of desmosomes in the ear plug formation in the bowhead whale (Balaena mysticetus)., PMID:31854140
Kallikreins: Essential epidermal messengers for regulation of the skin microenvironment during homeostasis, repair and disease., PMID:33543017
Proteomics Identification and Validation of Desmocollin-1 and Catechol-O-Methyltransferase as Proteins Associated with Breast Cancer Cell Migration and Metastasis., PMID:31617665
Immunohistochemical staining of skin-expressed proteins to identify exfoliated epidermal cells for forensic purposes., PMID:31550598
Ultraviolet light degrades the mechanical and structural properties of human stratum corneum., PMID:31419748
Depot-medroxyprogesterone acetate reduces genital cell-cell adhesion molecule expression and increases genital herpes simplex virus type 2 infection susceptibility in a dose-dependent fashion., PMID:31302121
A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa., PMID:31281635
Gcn5-mediated acetylation at MBF-regulated promoters induces the G1/S transcriptional wave., PMID:31260531
The Gossypium hirsutum TIR-NBS-LRR gene GhDSC1 mediates resistance against Verticillium wilt., PMID:30957942
Desmocollin 3 has a tumor suppressive activity through inhibition of AKT pathway in colorectal cancer., PMID:30857973
An essential role for dNTP homeostasis following CDK-induced replication stress., PMID:30674555
Nonclassical pemphigus with exclusively IgG anti-desmocollin 3-specific antibodies., PMID:30671942
JAK1/3 inhibition preserves epidermal morphology in full-thickness 3D skin models of atopic dermatitis and psoriasis., PMID:30357932
The INO80 complex activates the transcription of S-phase genes in a cell cycle-regulated manner., PMID:30134042
DSC1 channel-dependent developmental regulation of pyrethroid susceptibility in Drosophila melanogaster., PMID:29891372
HDLs and the pathogenesis of atherosclerosis., PMID:29561322
For research use only. Not for human or drug use.
