Catalog No.
YHG14501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln37-Gly250
Predicted molecular weight
26.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q07973
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CYP24A1, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450-CC24, 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, CYP24, Cytochrome P450 24A1
Attenuative Effect of Grifola frondosa (Maitake Mushroom) on Severe DSS-Induced Colitis in Vitamin D-Deficient Mice., PMID:40509673
Deciphering mitochondrial dysfunction in keratoconus: Insights into ACSL4 from machine learning-based bulk and single-cell transcriptome analyses and experimental validation., PMID:40496889
Inhibition of the RIPK4 enhances suppression of human melanoma growth through vitamin D signaling., PMID:40490050
Vitamin D and Neurodegenerative Diseases Such as Multiple Sclerosis (MS), Parkinson's Disease (PD), Alzheimer's Disease (AD), and Amyotrophic Lateral Sclerosis (ALS): A Review of Current Literature., PMID:40464816
EBV Reactivation-associated gene signature predicts poor prognosis in nasopharyngeal carcinoma., PMID:40457434
Phenotypes and the Importance of Genetic Analysis in Adult Patients with Nephrolithiasis and/or Nephrocalcinosis: A Single-Center Experience., PMID:40428323
1,25(OH)2D3 up-regulated mitochondrial dynamics and biogenesis to modulate steroidogenesis in the scent glands of muskrats (Ondatra zibethicus)., PMID:40398522
Genetic variants predisposing to increased risk of kidney stone disease., PMID:40372791
Induction of Cell Death and Regulation of Autocrine Vitamin D Metabolism in Cervical Cancer by Physiological and GI20 Doses of 25-Hydroxycholecalciferol., PMID:40362248
Vitamin D3, cholecalciferol via its hydroxylmetabolites, receptors and metabolizing enzymes modulates male reproductive functions., PMID:40320139
Drug-induced cis-regulatory elements in human hepatocytes affect molecular phenotypes associated with adverse reactions., PMID:40301309
The DHCR7 is the key target of lipotoxic liver injury caused by matrine through abnormal activation of the cholesterol synthesis pathway., PMID:40250732
Network pharmacology combined with transcriptomics reveals that Ganoderma lucidum spore and Sanghuangporus vaninii compound extract exerts anti-colorectal cancer effects via CYP24A1-mediated VDR pathway and TERT-mediated Wnt signaling pathway., PMID:40245966
Genetic insights into vitamin D deficiency: a case-control study of GC and CYP24A1 gene polymorphism., PMID:40199414
Genetic variants in vitamin D metabolism-related genes are associated with vitamin D status and adiposity markers., PMID:40187223
Association of PTH and vitamin D-related genes with dental development in Brazilian children: a cross-sectional study., PMID:40172435
Inherited and de novo variants in young females potentially associated with pelvic organ prolapse., PMID:40157519
Advance in candidate genes in mandibular retrognathism: A systematic review., PMID:40132276
Kidney deletions of Cyp27b1 fail to reduce serum 1,25(OH)2D3., PMID:40096920
The impact of inducible-whole body or intestine-specific Cyp24a1 gene knockout on vitamin D metabolism in mice., PMID:40096918
Longitudinal Evaluation of Vitamin D, Parathyroid Hormone, Antimicrobial Peptides, and Immunomodulatory Genes in Hospitalized Foals., PMID:40008921
Contributing role and molecular basis of Vitamin D/Vitamin D receptor deficiency in hyperhomocysteinemia-induced cardiac hypertrophy., PMID:39978691
CYP24A1 DNA Methylation in Colorectal Cancer as Potential Prognostic and Predictive Markers., PMID:39858498
Vitamin D-related genetic variants and prostate cancer risk in Black men., PMID:39823710
CYP24A1 is overexpressed in keloid keratinocytes and its inhibition alters profibrotic gene expression., PMID:39822648
Genetic Variants Associated with the Biochemical Response to Vitamin D3 in the Multi-Ethnic Study of Atherosclerosis., PMID:39815761
Differential Expression of Proteins Involved in Skin Barrier Maintenance and Vitamin D Metabolism in Atopic Dermatitis: A Cross-Sectional, Exploratory Study., PMID:39796069
The Expressions of the Immunity- and Muscle Development-Related Genes of 40-Day-Old Broilers Are Promoted in Response to the In Ovo and Dietary Supplemental Administration of Calcidiol in Conjunction with the In Ovo Administration of Marek's Disease Vaccine., PMID:39794953
CYP24A1 Binding to FUS Maintains Tumor Properties by Regulating the miR-200c/ZEB1/EMT Axis., PMID:39777777
Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities., PMID:39756914
Decoding the prognostic landscape of LUAD: the interplay between N6-methyladenosine modification and immune microenvironment., PMID:39720723
The vitamin D receptor TaqI TT genotype is associated with type 1 diabetes in the Black South African population., PMID:39703896
Intestinal Cyp24a1 regulates vitamin D locally independent of systemic regulation by renal Cyp24a1 in mice., PMID:39688907
Modulation of NRF2 and CYP24A1 Pathways by Hookah Smoke: Implications for Male Reproductive Health., PMID:39673488
Vitamin D and Molecules Related to Vitamin D Metabolism in Children with Sepsis., PMID:39659753
Allele C of rs6068816 in the CYP24A1 Gene is Associated with Increased Risk of Hyperuricemia in the Chinese Population: A Case-Control Study., PMID:39600277
Short-Term Effects of Escalating Doses of Cholecalciferol on FGF23 and 24,25(OH)2 Vitamin D Levels: A Preliminary Investigation., PMID:39519433
Correlation between vitamin D metabolic pathway-related gene polymorphisms and cardiovascular disease., PMID:39494806
Regulatory mechanisms and pathological implications of CYP24A1 in Vitamin D metabolism., PMID:39488987
Anticancer Activity of Vitamin D, Lumisterol and Selected Derivatives against Human Malignant Melanoma Cell Lines., PMID:39456696
Crosstalk between 1,25(OH)2-Vitamin D3 and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation., PMID:39447276
Investigating the Mechanisms of Anti-tumoral Effect of Combination Therapy of Calcitriol and Sodium Pentaborate Pentahydrate on HepG2 Hepatocellular Carcinoma Cells., PMID:39441231
SARS-CoV-2 infection causes a decline in renal megalin expression and affects vitamin D metabolism in the kidney of K18-hACE2 mice., PMID:39414885
Maternal loss of 24-hydroxylase causes increased intestinal calcium absorption and hypercalcemia during pregnancy but reduced skeletal resorption during lactation in mice., PMID:39385466
In Vivo Contribution of Cyp24a1 Promoter Vitamin D Response Elements., PMID:39363152
Targeting Calcitriol Metabolism in Acute Vitamin D Toxicity-A Comprehensive Review and Clinical Insight., PMID:39337491
Focusing on non-responders to infliximab with ulcerative colitis, what can we do first and next?, PMID:39191122
Paricalcitol prevents MAPK pathway activation and inflammation in adriamycin-induced kidney injury in rats., PMID:39183499
Single-cell transcriptomics reveals tumor landscape in ovarian carcinosarcoma., PMID:39155781
Gal-1-mediated cytochrome p450 activation promotes fibroblast into myofibroblast differentiation in pulmonary fibrosis., PMID:39137631
For research use only. Not for human or drug use.
