Catalog No.
YHG07301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro279-Val467
Predicted molecular weight
23.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q06033
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ITIH3, SHAP, ITI-HC3, Serum-derived hyaluronan-associated protein, Inter-alpha-inhibitor heavy chain 3, ITI heavy chain H3, Inter-alpha-trypsin inhibitor heavy chain H3
Proteomic-based biomarker discovery reveals panels of diagnostic biomarkers for early identification of heart failure subtypes., PMID:40375290
Identifying novel protein biomarkers with cross-psychiatric disorders effects and potential intervention targets: Evidence from proteomic-Mendelian randomization., PMID:40334965
Mendelian Randomization Analysis of the Possible Causal Relationships Between Neurodevelopment-Related Proteins and Bipolar Disorder., PMID:40123161
Quantitative proteomics identifies plasma protein alterations that associate with metabolic and thrombotic profile changes after bariatric surgery., PMID:40000393
NEK4: prediction of available drug targets and common genetic linkages in bipolar disorder and major depressive disorder., PMID:39950180
Exploring susceptibility and therapeutic targets for kidney stones through proteome-wide Mendelian randomization., PMID:39530187
Identification and validation of diagnostic genes associated with neutrophil extracellular traps of type 2 diabetes mellitus., PMID:39296548
Proteome-wide mendelian randomization identifies therapeutic targets for nephrolithiasis., PMID:39237840
Novel therapeutic targets for primary open-angle glaucoma identified through multicenter proteome-wide mendelian randomization., PMID:39221148
Identification of disease phenotypes in acetylcholine receptor-antibody myasthenia gravis using proteomics-based consensus clustering., PMID:38959848
Inter-alpha-trypsin inhibitor heavy chain H3 is a potential biomarker for disease activity in myasthenia gravis., PMID:38888758
Hepatokine ITIH3 protects against hepatic steatosis by downregulating mitochondrial bioenergetics and de novo lipogenesis., PMID:38689636
MSC-derived exosomes deliver ZBTB4 to mediate transcriptional repression of ITIH3 in astrocytes in spinal cord injury., PMID:38641154
Dissecting the shared genetic landscape of anxiety, depression, and schizophrenia., PMID:38637810
Targeted plasma proteomic analysis uncovers a high-performance biomarker panel for early diagnosis of gastric cancer., PMID:38631604
SERPINA3, FGA, AGP1, ITIH3 and SAA1 as novel biomarkers for eosinophilic granulomatosis with polyangiitis diagnosis and activity assessment., PMID:38552326
Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures., PMID:38477735
Exploration of potential biomarkers for early bladder cancer based on urine proteomics., PMID:38410113
A proteomic classifier panel for early screening of colorectal cancer: a case control study., PMID:38383428
Characteristics of changes in plasma proteome profiling after sleeve gastrectomy., PMID:38375199
Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development., PMID:38225249
Secreted proteins in plasma and placenta as novel non-invasive biomarkers for intrahepatic cholestasis of pregnancy: A case-control study., PMID:38027820
Integrated Transcriptomics-Proteomics Analysis Identifies Molecular Phenotypic Alterations Associated with Colorectal Cancer., PMID:37909265
Peptide-Coated Bacteriorhodopsin-Based Photoelectric Biosensor for Detecting Rheumatoid Arthritis., PMID:37887122
Conventional and genetic associations of adiposity with 1463 proteins in relatively lean Chinese adults., PMID:37676424
Luteolin Alleviates Liver Fibrosis in Rat Hepatic Stellate Cell HSC-T6: A Proteomic Analysis., PMID:37360572
Discovery and validation of serum glycoprotein biomarkers for high grade serous ovarian cancer., PMID:37147936
Alterations of plasma exosomal proteins and motabolies are associated with the progression of castration-resistant prostate cancer., PMID:36681849
Downregulation of ITIH3 contributes to cisplatin-based chemotherapy resistance in ovarian carcinoma via the Bcl-2 mediated anti-apoptosis signaling pathway., PMID:36644154
Maternal plasma proteome profiling of biomarkers and pathogenic mechanisms of early-onset and late-onset preeclampsia., PMID:36351970
Systemic Biomarkers and Unique Pathways in Different Phenotypes of Heart Failure with Preserved Ejection Fraction., PMID:36291628
Quantitative label-free proteomic analysis of human follicle fluid to identify novel candidate protein biomarker for endometriosis-associated infertility., PMID:35811008
Proteomics and Metabolomics Profiling of Platelets and Plasma Mediators of Thrombo-Inflammation in Gestational Hypertension and Preeclampsia., PMID:35455936
Regulatory Variant rs2535629 in ITIH3 Intron Confers Schizophrenia Risk By Regulating CTCF Binding and SFMBT1 Expression., PMID:34978167
A serum proteome signature to predict mortality in severe COVID-19 patients., PMID:34226277
A Comparative Analysis of the Lipoprotein(a) and Low-Density Lipoprotein Proteomic Profiles Combining Mass Spectrometry and Mendelian Randomization., PMID:34027348
Mechanism of Huayu Jianpi Fangshi decoction in urolithiasis prevention: a randomized trial., PMID:33832307
Changes on proteomic and metabolomic profile in serum of mice induced by chronic exposure to tramadol., PMID:33446901
Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits., PMID:32987857
A functional missense variant in ITIH3 affects protein expression and neurodevelopment and confers schizophrenia risk in the Han Chinese population., PMID:32712163
The plasma peptides of sepsis., PMID:32636717
Systemic Proteome Alterations Linked to Early Stage Pancreatic Cancer in Diabetic Patients., PMID:32545216
Integrative analyses indicate an association between ITIH3 polymorphisms with autism spectrum disorder., PMID:32251353
Novel genetic susceptibility loci identified by family based whole exome sequencing in Han Chinese schizophrenia patients., PMID:32066673
Revelation of Proteomic Indicators for Colorectal Cancer in Initial Stages of Development., PMID:32023884
Genetic variants associated with psychotic symptoms across psychiatric disorders., PMID:31945448
The plasma peptides of breast versus ovarian cancer., PMID:31889940
Plasma Protein Comparison between Dairy Cows with Inactive Ovaries and Estrus., PMID:31548586
Plasma Inter-Alpha-Trypsin Inhibitor Heavy Chains H3 and H4 Serve as Novel Diagnostic Biomarkers in Human Colorectal Cancer., PMID:31481982
Bioinformatic Analysis of Gene Variants from Gastroschisis Recurrence Identifies Multiple Novel Pathogenetic Pathways: Implication for the Closure of the Ventral Body Wall., PMID:31075877
For research use only. Not for human or drug use.
