Catalog No.
YHG05401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly213-Lys463
Predicted molecular weight
29.21 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q05639
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Elongation factor 1-alpha 2, EEF1AL, Eukaryotic elongation factor 1 A-2, eEF1A-2, EF-1-alpha-2, Statin-S1, STN, EEF1A2
Function of eEF-1γ in the nucleus in response to insulin in hepatocellular carcinoma cells., PMID:40442278
UGDH promotes 5-fluorouracil resistance in colorectal cancer via the ROS-activated PI3K/AKT-EEF1A2-PRDX1 pathway., PMID:40311992
Exploration of RNA-binding proteins identified RPS27 as a potential regulator associated with Kaposi's sarcoma development., PMID:40016701
Variations in rumen microbiota and host genome impacted feed efficiency in goat breeds., PMID:39944650
Bisphenol B restrains rat leydig cell function via H3K27me3/H3K9me3 histone modifications., PMID:39919587
Trideoxycytidine Diphosphate Promotes Neural Stem Cell Proliferation and Neurogenesis in Mice., PMID:39736328
[Analysis of EEF1A2 gene variant in a child with Global developmental delay]., PMID:39528280
Prognostic biomarkers based on GUF1, EFTUD2 and GSPT1 targets affecting migration of gastric cancer cells., PMID:39430826
[Rett syndrome-like phenotype caused by EEF1A2 gene in 2 children]., PMID:39429087
EEF1A2 identified as a hub gene associated with the severity of metabolic dysfunction-associated steatotic liver disease., PMID:39414652
N-Acetylcysteine Inhibits Coxsackievirus B3 Replication by Downregulating Eukaryotic Translation Elongation Factor 1 Alpha 1., PMID:39339978
Regulation of Nrf2/A20/eEF1A2 Axis by Ginsenoside Rb1: A Key Pathway in Alleviating Cerebral Ischemia-Reperfusion Injury., PMID:39190389
Ac4C modification of lncRNA SIMALR promotes nasopharyngeal carcinoma progression through activating eEF1A2 to facilitate ITGB4/ITGA6 translation., PMID:39154122
[Developmental and epileptic encephalopathy 33 caused by EEF1A2 gene mutation: a case report]., PMID:39148392
Identification of anoikis-related gene signatures and construction of the prognosis model in prostate cancer., PMID:38957390
Broadening the scope of multigene panel analysis for adult epilepsy patients., PMID:38946282
High expression of eukaryotic elongation factor 1-alpha-2 in lung adenocarcinoma is associated with poor prognosis., PMID:38874190
DNA methylation profiling identifies epigenetic signatures of early gastric cancer., PMID:38507065
eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer., PMID:38442201
Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis., PMID:38360885
KAT8-catalyzed lactylation promotes eEF1A2-mediated protein synthesis and colorectal carcinogenesis., PMID:38359291
Expansion of the neurodevelopmental phenotype of individuals with EEF1A2 variants and genotype-phenotype study., PMID:38355961
A pan-cancer analysis of the prognosis and immune infiltration of eEF1A2 and its potential function in thyroid carcinoma., PMID:38314298
Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach., PMID:38220433
Face-valid phenotypes in a mouse model of the most common mutation in EEF1A2-related neurodevelopmental disorder., PMID:38179821
[Role of Eukaryotic Translation Elongation Factor 1 Family Members in the Tumorigenesis and Progression of Lung Adenocarcinoma]., PMID:38173097
Oncogenic activation of EEF1A2 expression: a journey from a putative to an established oncogene., PMID:38172654
EEF1A2 promotes HIF1A mediated breast cancer angiogenesis in normoxia and participates in a positive feedback loop with HIF1A in hypoxia., PMID:38012382
PCMT1 knockdown attenuates malignant properties by globally regulating transcriptome profiles in triple-negative breast cancer cells., PMID:37953789
Hypoxia-induced circ-CDYL-EEF1A2 transcriptional complex drives lung metastasis of cancer stem cells from hepatocellular carcinoma., PMID:37852428
Inflammatory cytokine-regulated LNCPTCTS suppresses thyroid cancer progression via enhancing Snail nuclear export., PMID:37741431
Multi-omics approaches identify novel prognostic biomarkers of autophagy in uveal melanoma., PMID:37725244
Autism- and epilepsy-associated EEF1A2 mutations lead to translational dysfunction and altered actin bundling., PMID:37695913
The anoikis-related gene signature predicts survival accurately in colon adenocarcinoma., PMID:37626132
Eukaryotic Elongation Factor 1Alpha-2 (EEF1A2) Participates in the Progression of Gastric Cancer via Interaction with Heat Shock Protein B8 (HSPB8)., PMID:37437931
Immunoproteasome-specific subunit PSMB9 induction is required to regulate cellular proteostasis upon mitochondrial dysfunction., PMID:37433777
Endogenous epitope tagging of eEF1A2 in mice reveals early embryonic expression of eEF1A2 and subcellular compartmentalisation of neuronal eEF1A1 and eEF1A2., PMID:37429391
Biliverdin modulates the Nrf2/A20/eEF1A2 axis to alleviate cerebral ischemia-reperfusion injury by inhibiting pyroptosis., PMID:37399716
Autism- and epilepsy-associated EEF1A2 mutations lead to translational dysfunction and altered actin bundling., PMID:37333416
A Case-Control Study by ddPCR of ALU 260/111 and LINE-1 266/97 Copy Number Ratio in Circulating Cell-Free DNA in Plasma Revealed LINE-1 266/97 as a Potential Biomarker for Early Breast Cancer Detection., PMID:37239866
Human Tissues Exhibit Diverse Composition of Translation Machinery., PMID:37176068
EEF1A2 accelerates the protein translation of chemokine in rat myocardial cells induced by ischemia-reperfusion., PMID:37101626
The eEF1 family of mammalian translation elongation factors., PMID:37082266
eEF1A2 siRNA Suppresses MPP+-Induced Activation of Akt and mTOR and Potentiates Caspase-3 Activation in a Parkinson's Disease Model., PMID:37051183
MicroRNA control of the myogenic cell transcriptome and proteome: the role of miR-16., PMID:36971422
High-throughput proteomic characterization of seminal plasma from bulls with contrasting semen quality., PMID:36714547
Associative analysis of multi-omics data indicates that acetylation modification is widely involved in cigarette smoke-induced chronic obstructive pulmonary disease., PMID:36714109
Analysis of eEF1A2 gene expression and copy number in cervical carcinoma., PMID:36637958
Detection of mosaic variants using genome sequencing in a large pediatric cohort., PMID:36563179
KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells., PMID:36470917
For research use only. Not for human or drug use.
