Catalog No.
YHF96101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu37-Leu461
Predicted molecular weight
52.39 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02818
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NUC, CALNUC, NUCB1, Nucleobindin-1
Causal effects and plasma protein mediators between type 2 diabetes and erectile dysfunction: a Mendelian randomization study., PMID:40463815
Nesfatin-1 Suppresses Inflammation in Bronchopulmonary Dysplasia by Regulating HMGB-1/TLR4/p65/NLRP3 Signaling Pathway., PMID:40415368
Acute effects of peripherally administered nicotine on food intake via the central anorectic peptide nesfatin-1/nucleobindin-2 in adult male rats., PMID:40368052
Psilocybin and ketamine affect novel neuropeptides gene expression in the rat hypothalamus., PMID:40243003
Comprehensive Proteomics and Machine Learning Analysis to Distinguish Follicular Adenoma and Follicular Thyroid Carcinoma from Indeterminate Thyroid Nodules., PMID:40205804
Preventive administration of shengmaiyin: a novel approach to counteract heatstroke-induced coagulopathy in rats., PMID:40160464
Nesfatin-1 Neurons in the Ventral Premammillary Nucleus Integrate Metabolic and Reproductive Signals in Male Rats., PMID:39859453
Molecular tag for promoting N-glycan maturation in the cargo receptor-mediated secretion pathway., PMID:39717080
Nesfatin-1 is involved in hyperbaric oxygen-mediated therapeutic effects in high fat diet-induced hyperphagia in mice., PMID:39706341
Intestinal NUCB2/nesfatin-1 regulates hepatic glucose production via the MC4R-cAMP-GLP-1 pathway., PMID:39562740
ER export via SURF4 uses diverse mechanisms of both client and coat engagement., PMID:39531033
Central NUCB2/nesfatin-1 signaling ameliorates liver steatosis through suppression of endoplasmic reticulum stress in the hypothalamus., PMID:39389418
Thermal modulation of energy allocation during sex determination in the European sea bass (Dicentrarchus labrax)., PMID:38925525
Nesfatin-1 and nesfatin-1-like peptide attenuate hepatocyte lipid accumulation and nucleobindin-1 disruption modulates lipid metabolic pathways., PMID:38802487
A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning., PMID:38760690
NUCB1 is required for proper insulin signaling to control longevity in Drosophila., PMID:38509017
Suppressive action of nesfatin-1 and nesfatin-1-like peptide on cortisol synthesis in human adrenal cortex cells., PMID:38368491
The proteome and phosphoproteome of circulating extracellular vesicle-enriched preparations are associated with characteristic clinical features in type 1 diabetes., PMID:37576973
Expression and correlation of COX-2 and NUCB1 in colorectal adenocarcinoma., PMID:37547718
Calnuc-derived nesfatin-1-like peptide is an activator of tumor cell proliferation and migration., PMID:37539786
The RNA-Binding and RNA-Melting Activities of the Multifunctional Protein Nucleobindin 1., PMID:37047165
Identification of MKNK1 and TOP3A as ovarian endometriosis risk-associated genes using integrative genomic analyses and functional experiments., PMID:36851918
Does NUCB2/Nesfatin-1 Influence Eating Behaviors in Obese Patients with Binge Eating Disorder? Toward a Neurobiological Pathway., PMID:36678225
Meta-Analysis of MS-Based Proteomics Studies Indicates Interferon Regulatory Factor 4 and Nucleobindin1 as Potential Prognostic and Drug Resistance Biomarkers in Diffuse Large B Cell Lymphoma., PMID:36611989
Pursuing Diabetic Nephropathy through Aqueous Humor Proteomics Analysis., PMID:36211816
Possible Association of Nucleobindin-1 Protein with Depressive Disorder in Patients with HIV Infection., PMID:36138887
Multi-Omics Approach to Elucidate Cerebrospinal Fluid Changes in Dogs with Intervertebral Disc Herniation., PMID:34769107
Nesfatin-1-like peptide is a negative regulator of cardiovascular functions in zebrafish and goldfish., PMID:34453930
Nucleobindin-derived nesfatin-1 and nesfatin-1-like peptide stimulate pro-opiomelanocortin synthesis in murine AtT-20 corticotrophs through the cAMP/PKA/CREB signaling pathway., PMID:34302909
NUCB1 Suppresses Growth and Shows Additive Effects With Gemcitabine in Pancreatic Ductal Adenocarcinoma via the Unfolded Protein Response., PMID:33855021
Nesfatin-1 and Nesfatin-1-like peptide suppress basal and TRH-Induced expression of prolactin and prolactin regulatory element-binding protein mRNAs in rat GH3 somatolactotrophs., PMID:33819522
Tumour-derived Dilp8/INSL3 induces cancer anorexia by regulating feeding neuropeptides via Lgr3/8 in the brain., PMID:33558728
Nesfatin-1 and nesfatin-1-like peptide suppress growth hormone synthesis via the AC/PKA/CREB pathway in mammalian somatotrophs., PMID:33028951
Nesfatin-1-like peptide suppresses hypothalamo-pituitary-gonadal mRNAs, gonadal steroidogenesis, and oocyte maturation in fish†., PMID:32542346
Nucleobindin-1 regulates ECM degradation by promoting intra-Golgi trafficking of MMPs., PMID:32479594
Proteomic analysis of oxidative stress response in human umbilical vein endothelial cells (HUVECs): role of heme oxygenase 1 (HMOX1) in hypoxanthine-induced oxidative stress in HUVECs., PMID:32420127
Effects of feeding status on nucb1 and nucb2A mRNA expression in the hypothalamus of Schizothorax davidi., PMID:32130563
Fine mapping and identification of serum urate loci in American Indians: The Strong Heart Family Study., PMID:31784582
Genetic analyses uncover pleiotropic compensatory roles for Drosophila Nucleobindin-1 in inositol trisphosphate-mediated intracellular calcium homeostasis., PMID:31557446
Molecular evolution guided functional analyses reveals Nucleobindin-1 as a canonical E-box binding protein promoting Epithelial-to-Mesenchymal transition (EMT)., PMID:31176806
Nucleobindins and encoded peptides: From cell signaling to physiology., PMID:31036300
Conformation-specific antibodies against multiple amyloid protofibril species from a single amyloid immunogen., PMID:30663210
Irisin interaction with adipose tissue secretions by exercise training and flaxseed oil supplement., PMID:30654813
Centrally administered kisspeptin suppresses feeding via nesfatin-1 and oxytocin in male rats., PMID:30562556
Increasing hypothalamic nucleobindin 2 levels and decreasing hypothalamic inflammation in obese male mice via diet and exercise alleviate obesity-associated hypogonadism., PMID:30503692
Nesfatin-130-59 Injected Intracerebroventricularly Increases Anxiety, Depression-Like Behavior, and Anhedonia in Normal Weight Rats., PMID:30513901
Direct effects of neuropeptide nesfatin-1 on testicular spermatogenesis and steroidogenesis of the adult mice., PMID:30391240
Nesfatin-1/Nucleobindin-2 Is a Potent Prognostic Marker and Enhances Cell Proliferation, Migration, and Invasion in Bladder Cancer., PMID:30327690
Protective effects of Nesfatin-1 peptide on cerebral ischemia reperfusion injury via inhibition of neuronal cell death and enhancement of antioxidant defenses., PMID:30269302
Evaluation of ghrelin, nesfatin-1 and irisin levels of serum and brain after acute or chronic pentylenetetrazole administrations in rats using sodium valproate., PMID:30111257
For research use only. Not for human or drug use.
