Recombinant Human MUC3A Protein, N-GST

Catalog No.

YHF94201

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Cys2958-Ala3062

Predicted molecular weight

38.61 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q02505

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Intestinal mucin-3A, MUC3A, MUC-3A, Mucin-3A, MUC3

High Tumor Mutation Burden (TMB) and a Novel Somatic Mutation in the TREX1 Gene in a Patient with Aggressive and Refractory High-Grade B-Cell Lymphoma: A Case Report., PMID:40243506

Decoding the Genetic Basis of Mast Cell Hypersensitivity and Infection Risk in Hypermobile Ehlers-Danlos Syndrome., PMID:39451569

Mucin 3A's Promotion of the Proliferation and Migration of Gastric Cancer Cells Through Activation of the mTOR Pathway., PMID:38758153

The CC2D2B is a novel genetic modifier of the clinical phenotype in patients with hereditary angioedema due to C1 inhibitor deficiency., PMID:38679185

Preventative Effects of Milk Fat Globule Membrane Ingredients on DSS-Induced Mucosal Injury in Intestinal Epithelial Cells., PMID:38612988

[Clinicopathological and molecular genetic features of Crohn's disease]., PMID:38556818

Decoding the expression pattern of MUC3A in gastric adenocarcinoma: unveiling the key to successful immunotherapy., PMID:38069509

Mucins 3A and 3B Are Expressed in the Epithelium of Human Large Airway., PMID:37686350

Malakoplakia with aberrant ALK expression by immunohistochemistry: a case report., PMID:37644531

Effects of soluble glucomannan and insoluble cellulose treatment on mucin secretion and mucin glycosylation-related gene expression in the colons of mice., PMID:37440706

Variants of Human Mucin Genes in Clear Cell Renal Cell Carcinoma and their Potential Prognostic and Predictive Values., PMID:37283258

Lactobacillus GG is associated with mucin genes expressions in type 2 diabetes mellitus: a randomized, placebo-controlled trial., PMID:36997822

Identification of Genetic Alterations in Rapid Progressive Glioblastoma by Use of Whole Exome Sequencing., PMID:36980325

Sex-Specific Whole-Transcriptome Analysis in the Cerebral Cortex of FAE Offspring., PMID:36672262

Whole-exome sequencing identifies a set of genes as markers of hepatocellular carcinoma early recurrence., PMID:36550350

Discovery of a MUC3B gene reconstructs the membrane mucin gene cluster on human chromosome 7., PMID:36256656

Aberrant Mucin Expression Profiles Associate With Pediatric Inflammatory Bowel Disease Presentation and Activity., PMID:36239641

Subchronic exposure to environmentally relevant concentrations of di-(2-ethylhexyl) phthalate differentially affects the colon and ileum in adult female mice., PMID:36209858

Expression of Mucin Family Proteins in Non-Small-Cell Lung Cancer and its Role in Evaluation of Prognosis., PMID:36059804

Genomic Characterization by Whole-Exome Sequencing of Hypermobility Spectrum Disorder., PMID:35886052

MUC3A promotes the progression of colorectal cancer through the PI3K/Akt/mTOR pathway., PMID:35655161

Molecular characterization of vascular intestinal obstruction using whole-exome sequencing., PMID:35571423

LINC00173 promotes Wilms' tumor progression through MGAT1-mediated MUC3A N-glycosylation., PMID:35491865

Anemone chinensis Bunge aqueous enema alleviates dextran sulfate sodium-induced colitis via inhibition of inflammation and regulation of the colonic mucosal microbiota., PMID:34998930

Whole Exome Sequencing Identifies Two Novel Mutations in a Patient with UC Associated with PSC and SSA., PMID:34545326

The Impact of Di-Isononyl Phthalate Exposure on Specialized Epithelial Cells in the Colon., PMID:34453847

MUC3A promotes non-small cell lung cancer progression via activating the NFκB pathway and attenuates radiosensitivity., PMID:34326691

Systems Immunology Analysis Reveals the Contribution of Pulmonary and Extrapulmonary Tissues to the Immunopathogenesis of Severe COVID-19 Patients., PMID:34262555

MUC3A induces PD-L1 and reduces tyrosine kinase inhibitors effects in EGFR-mutant non-small cell lung cancer., PMID:33994852

Biliary microbiota and mucin 4 impact the calcification of cholesterol gallstones., PMID:33341401

KIAA1429 promotes the progression of lung adenocarcinoma by regulating the m6A level of MUC3A., PMID:33249400

Mucin mutations and aberrant expression are associated with the pathogenesis of immune thrombocytopenia., PMID:33213847

[Whole exome sequencing in a pedigree with ankylosing spondylitis]., PMID:32700495

Transcriptional Signatures That Define Ulcerative Colitis in Remission., PMID:32322884

Serum mucin 3A as a potential biomarker for extrahepatic cholangiocarcinoma., PMID:32270773

Cronkhite-Canada syndrome complicated with three malignant tumors: a case report and whole exome sequencing analysis., PMID:31764169

Mucins are Involved in the Intestinal Permeation of Lipophilic Drugs in the Proximal Region of Rat Small Intestine., PMID:31529336

Non-Invasive Evaluation of Extracellular Matrix Formation in the Intestinal Epithelium., PMID:30417287

MSLN (Mesothelin), ANTXR1 (TEM8), and MUC3A are the potent antigenic targets for CAR T cell therapy of gastric adenocarcinoma., PMID:30260046

Whole Exome Sequencing Identifies New Host Genomic Susceptibility Factors in Empyema Caused by Streptococcus pneumoniae in Children: A Pilot Study., PMID:29751582

[Association between chronicity of HBV infection and host immunity]., PMID:27465957

Increased expression of MUC3A is associated with poor prognosis in localized clear-cell renal cell carcinoma., PMID:27374181

Lactobacillus acidophilus binds to MUC3 component of cultured intestinal epithelial cells with highest affinity., PMID:26946538

Deoxynivalenol inhibits the expression by goblet cells of intestinal mucins through a PKR and MAP kinase dependent repression of the resistin-like molecule β., PMID:25727397

Comprehensive characterization of the genomic alterations in human gastric cancer., PMID:25422082

Enterotoxigenic Escherichia coli secretes a highly conserved mucin-degrading metalloprotease to effectively engage intestinal epithelial cells., PMID:24478067

Enhanced membrane-tethered mucin 3 (MUC3) expression by a tetrameric branched peptide with a conserved TFLK motif inhibits bacteria adherence., PMID:23316049

Gene expression profile of a newly established choriocarcinoma cell line, iC3-1, compared to existing choriocarcinoma cell lines and normal placenta., PMID:23199791

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation., PMID:22990020

Combined evaluation of CK5/6, ER, p63, and MUC3 for distinguishing breast intraductal papilloma from ductal carcinoma in situ., PMID:22612506

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