Catalog No.
YHF93801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu50-Pro548
Predicted molecular weight
52.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02413
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DGI, Cadherin family member 4, Desmoglein-1, DG1, Pemphigus foliaceus antigen, CDHF4, DSG1, Desmosomal glycoprotein 1
Gene expression study in the siRNA based aniridia cell model and in primary aniridia limbal epithelial cells following duloxetine and ritanserin treatment., PMID:40493651
Factors associated with persistent anti-desmoglein positivity after remission in pemphigus vulgaris: a prospective registry-based cohort study., PMID:40433384
Discovery of new protein partners of anterior gradient 2 (AGR2) from cell-cell adhesion pathway using genetically-encoded photo-crosslinker DiZPK., PMID:40367911
Synergistic Enhancement of Compromised Skin Radiance: A Clinical Investigation of Prinsepia utilis Royle Polysaccharides and Nonapeptide Co-Application., PMID:40367144
Loss-of-function variants in DUSP1 encoding dual specificity phosphatase 1 cause palmoplantar keratoderma., PMID:40359362
Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome., PMID:40344324
Effect of isolated keratin 3 knockdown on gene expression of primary limbal epithelial cells without and with inflammatory stimuli., PMID:40334825
Epac1 contributes to apremilast-mediated rescue of pemphigus autoantibody-induced loss of keratinocyte adhesion., PMID:40299565
The Overlap of Allergic Disorders and Upper Gastrointestinal Symptoms: Beyond Eosinophilic Esophagitis., PMID:40284218
OsBSK3 and OsBSK2 regulate grain size and leaf angle via MAPK signaling pathway in rice., PMID:40254664
Clinical Responses and Transcriptomic Analysis of Spesolimab in a Girl With Severe Dermatitis, Multiple Allergies and Metabolic Wasting Syndrome., PMID:40207438
Epitomic profiling and functional characteristics of pemphigus vulgaris autoantibody binding to keratinocyte M3 muscarinic acetylcholine receptor., PMID:40120680
Decreased PAX6 and DSG1 Protein Expression in Corneal Epithelium of Patients with Epithelial Basal Membrane Dystrophy, Salzmann Nodular Degeneration, and Pterygium., PMID:40094891
Clinical Features, Diagnosis and Treatment of Different Types of Paediatric Pemphigus., PMID:40059466
Prevalence and pathogenic activity of anti-desmocollin-3 antibodies in patients with pemphigus vulgaris and pemphigus foliaceus., PMID:39989391
The Identification of FN1 as an Early Diagnostic Marker for Recurrent Abortion by Single-Exosome Profiling., PMID:39963517
Optimizing Pemphigus Management With Rituximab and Short-Term Relapse Predictors., PMID:39908046
The impact of signaling pathways on the desmosome ultrastructure in pemphigus., PMID:39882246
Pemphigus Foliaceus Mimicking Ichthyosis: A Rare Clinical Presentation., PMID:39734965
G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo., PMID:39650661
SAM Syndrome Presenting With Pulmonary Stenosis: A Case Report and Literature Review., PMID:39644136
Clinical and Genetic Findings in Patients With Palmoplantar Keratoderma., PMID:39630431
The transmembrane domain of the desmosomal cadherin desmoglein-1 governs lipid raft association to promote desmosome adhesive strength., PMID:39504468
Striate palmoplantar keratoderma: a novel DSG1 mutation, combined with an LDLR mutation., PMID:39503931
Pemphigus relapse: Mechanisms, risk factors, and agents associated with disease recurrence., PMID:39460496
Estradiol-mediated enhancement of the human ectocervical epithelial barrier correlates with desmoglein-1 expression in the follicular menstrual phase., PMID:39439565
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
Human dental mesenchymal stem cells restorate immune response in sera of pemphigus vulgaris patients., PMID:39352524
Persistent desmoglein-1 downregulation and periostin accumulation in histologic remission of eosinophilic esophagitis., PMID:39343172
Effect of Ritanserin and Duloxetine on the Gene Expression of Primary Aniridia and Healthy Human Limbal Stromal Cells, In Vitro., PMID:39306593
Effect of opioid receptor antagonist on mitigating tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-induced apoptolysis in pemphigus pathogenesis., PMID:39276627
Comparison of serum cytokines and chemokines levels and clinical significance in patients with pemphigus vulgaris-A retrospective study., PMID:39246287
shRNA-Targeting Caspase-3 Inhibits Cell Detachment Induced by Pemphigus Vulgaris Autoantibodies in HaCaT Cells., PMID:39201550
Pathogenic relevance of antibodies against desmoglein 3 in patients with oral lichen planus., PMID:39152677
Biomarkers in Pemphigus Vulgaris: A Systematic Review., PMID:39075718
Immunohistopathological analyses of a case of pemphigus vegetans with antibodies against desmoglein 1 and desmocollins 1-3., PMID:39073162
Effect of benralizumab on histopathology and inflammatory signatures in a clinical cohort of eosinophilic esophagitis., PMID:38986036
Factors associated with non-pathogenic antibodies against desmoglein-3 in pemphigus foliaceus., PMID:38851894
S100A11 is involved in the progression of colorectal cancer through the desmosome-catenin-TCF signaling pathway., PMID:38842658
The transmembrane domain of the desmosomal cadherin desmoglein-1 governs lipid raft association to promote desmosome adhesive strength., PMID:38712246
Experimental interventions attenuate a conjunctival epidermal metaplasia model., PMID:38679224
EGFR Inhibition by Erlotinib Rescues Desmosome Ultrastructure and Keratin Anchorage and Protects against Pemphigus Vulgaris IgG-Induced Acantholysis in Human Epidermis., PMID:38642796
Clinical and immunological predictors of post-rituximab paradoxical pemphigus flare: A prospective cohort study., PMID:38595008
Comparative Characterization of Human Meibomian Glands, Free Sebaceous Glands, and Hair-Associated Sebaceous Glands Based on Biomarkers, Analysis of Secretion Composition, and Gland Morphology., PMID:38542083
Rituximab in the Management of Autoimmune Bullous Diseases: A Treatment-Resistant Case Series from a Single Central European Referral Center., PMID:38399557
Necrotic activity of ExhC from Mammaliicoccus sciuri is mediated by specific amino acid residues., PMID:38287568
Sustained Remission Without Corticosteroids Among Patients With Pemphigus Who Had Rituximab as First-Line Therapy: Follow-Up of the Ritux 3 Trial., PMID:38265821
Unravelling the mystery: severe dermatitis, multiple allergies and metabolic wasting (SAM) syndrome with a novel homozygous mutation in DSG1., PMID:38240109
JNK inhibition enhances cell-cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes., PMID:38227055
A case of anti-laminin γ1 (p200) pemphigoid developed after dipeptidyl peptidase-4 inhibitor administration., PMID:38214494
For research use only. Not for human or drug use.
