Catalog No.
YHF90801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Trp683-Thr923
Predicted molecular weight
53.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01974
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ROR2, Neurotrophic tyrosine kinase, receptor-related 2, NTRKR2, Tyrosine-protein kinase transmembrane receptor ROR2
Non-canonical Wnt co-receptors ROR1/ROR2 are differentially regulated by hypoxia in colon cancer cells., PMID:40268059
Preclinical development of ozuriftamab vedotin (BA3021), a novel ROR2-specific conditionally active biologic antibody-drug conjugate., PMID:40202784
Challenging diagnosis in pulmonary nut carcinoma: A report of two cases with different histopathologic and molecular features and a novel NUTM1::SPECC1 gene fusion., PMID:40152114
Smoking aggravates neovascular age-related macular degeneration via Sema4D-PlexinB1 axis-mediated activation of pericytes., PMID:40121188
Identification of Wnt-5a Receptors Important in Diabetic and Non-Diabetic Corneal Epithelial Wound Healing., PMID:39998459
Punicalagin ameliorates lipopolysaccharide-induced inflammatory response in dental pulp cells via inhibition of the NF-κB/Wnt5a-ROR2 pathway., PMID:39994845
ROR2 drives right ventricular heart failure via disruption of proteostasis., PMID:39975092
Genetic insights into avian influenza resistance in Jeju Island chickens: the roles of Mx1 and oligoadenylate synthetase-like single nucleotide polymorphisms., PMID:39974787
Amyloid-β can activate JNK signalling via WNT5A-ROR2 to reduce synapse formation in Alzheimer's disease., PMID:39907042
A-to-I-Edited miR-1304-3p Inhibits Glycolysis and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inactivating Wnt5a/ROR2 Signaling., PMID:39763297
WNT4 promotes the symmetric fission of crypt in radiation-induced intestinal epithelial regeneration., PMID:39725925
Immunohistochemical Expression of ROR2 in Gastrointestinal Stromal Tumor., PMID:39607525
Accelerating CAR-T Cell Therapies with Small-Molecule Inhibitors., PMID:39589646
Twofold Expression of Receptor Tyrosine Kinase 2 (ROR2) in Giant Cell Tumors of Bone: Outcome of a Case‒Control Study., PMID:39555360
Ror2 signaling regulated by differential Wnt proteins determines pathological fate of muscle mesenchymal progenitors., PMID:39468010
Neuroinflammatory Pathways Associated with Chronic Post-Thoracotomy Pain: A Review of Current Literature., PMID:39467985
WNT1/ROR2 pathway enhances the Triple-Negative breast cancer invasion, migration, and Epithelial-Mesenchymal transition., PMID:39428718
Brainstem transcriptomic changes in male Wistar rats after acute stress, comparing the use of duplex specific nuclease (DSN)., PMID:39300279
Wnt family members regulating osteogenesis and their origins., PMID:39283365
Two functional forms of the Meckel-Gruber syndrome protein TMEM67 generated by proteolytic cleavage by ADAMTS9 mediate Wnt signaling and ciliogenesis., PMID:39282264
Single-nucleus RNA sequencing reveals cell types, genes, and regulatory factors influencing melanogenesis in the breast muscle of Xuefeng black-bone chicken., PMID:39278114
Tetrandrine ameliorated atherosclerosis in vitamin D3/high cholesterol diet-challenged rats via modulation of miR-34a and Wnt5a/Ror2/ABCA1/NF-kB trajectory., PMID:39266573
Loss of PRICKLE1 leads to abnormal endometrial epithelial architecture, decreased embryo implantation, and reduced fertility in mice., PMID:39211179
Exploring the Logic and Conducting a Comprehensive Evaluation of the Adiponectin Receptor Agonists AdipoRon and AdipoAI's Impacts on Bone Metabolism and Repair-A Systematic Review., PMID:39206478
ROR2 promotes cell cycle progression and cell proliferation through the PI3K/AKT signaling pathway in gastric cancer., PMID:39150155
Down-regulation of PCBP2 suppresses the invasion and migration of trophoblasts via the WNT5A/ROR2 pathway in preeclampsia†., PMID:39115369
Wnt-5a-Receptor Tyrosine Kinase-Like Orphan Receptor 2 Signaling Provokes Metastatic Colonization and Angiogenesis in Renal Cell Carcinoma, and Prunetin Supresses the Axis Activation., PMID:39069169
Hepatopancreas Transcriptome Analysis of Spinibarbus sinensis to Reveal Different Growth-Related Genes., PMID:39062728
ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma., PMID:38975886
Receptor tyrosine kinase-like orphan receptor serves as a potential target in cancer immunotherapy., PMID:38973261
ROR2 promotes invasion and chemoresistance of triple-negative breast cancer cells by activating PI3K/AKT/mTOR signaling., PMID:38948021
Characterization of Wnt Signaling Pathway Aberrations in Metastatic Prostate Cancer., PMID:38912907
Genomic insights into adaptation to bipedal saltation and desert-like habitats of jerboas., PMID:38902451
Human Genetics of Ventricular Septal Defect., PMID:38884729
Structure and function of the ROR2 cysteine-rich domain in vertebrate noncanonical WNT5A signaling., PMID:38780011
[Genetic analysis of a Chinese pedigree affected with Brachydactyly type B1 due to a novel variant of ROR2 gene]., PMID:38684301
miR-124-3p and miR-194-5p regulation of the PI3K/AKT pathway via ROR2 in medulloblastoma progression., PMID:38632356
A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell., PMID:38589397
Role of the Ror family receptors in Wnt5a signaling., PMID:38587578
Establishment and molecular characterization of HCB-541, a novel and aggressive human cutaneous squamous cell carcinoma cell line., PMID:38565739
Characterization and impact of non-canonical WNT signaling on outcomes of urothelial carcinoma., PMID:38558536
A Crosstalk between the Receptor Tyrosine Kinase-Like Orphan Receptors ROR1/2 and S1P Signaling Pathways in Lung Cancer., PMID:38546054
Role of Wnt5b-Ror1 signaling in the proliferation of pancreatic ductal adenocarcinoma cells., PMID:38531660
Prenatal diagnosis of ROR-2 related Robinow syndrome presenting with fetal ultrasound findings of mesomelia, vertebral, digital and genital abnormalities., PMID:38504427
Increased Wnt5a/ROR2 signaling is associated with chondrogenesis in meniscal degeneration., PMID:38440852
HSPB1 as an RNA-binding protein mediates the pathological process of osteoarthritis., PMID:38429742
ROR2/Wnt5a Signaling Regulates Directional Cell Migration and Early Tumor Cell Invasion in Ovarian Cancer., PMID:38334461
ROR2 expression predicts human induced pluripotent stem cell differentiation into neural stem/progenitor cells and GABAergic neurons., PMID:38184695
Cytoneme-mediated transport of active Wnt5b-Ror2 complexes in zebrafish., PMID:38123680
FAT4 loss initiates hepatocarcinogenesis through the switching of canonical to noncanonical WNT signaling pathways., PMID:38055646
For research use only. Not for human or drug use.
