Catalog No.
YHF87801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Glu196
Predicted molecular weight
24.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01543
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Friend leukemia integration 1 transcription factor, Proto-oncogene Fli-1, Transcription factor ERGB, FLI1
EWSR1 Rearrangements in Basaloid Neoplasms With Adnexal Differentiation., PMID:40511965
Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC., PMID:40494892
Immune-related gene risk model establishment and role of key gene FUCA1 in malignant pleural mesothelioma., PMID:40487392
Histone deacetylase inhibitors target DNA replication regulators and replication stress in Ewing sarcoma cells., PMID:40478628
Phase separation of the oncogenic fusion protein EWS::FLI1 is modulated by its DNA-binding domain., PMID:40377985
High Tau expression correlates with reduced invasion and prolonged survival in Ewing sarcoma., PMID:40319030
Role of Transcription Factor Fli-1 in Inflammation and Autoimmune Diseases., PMID:40305194
LOXHD1 is an oncofusion-regulated antigen of ewing sarcoma., PMID:40234527
Utility of Protein Kinase C Beta II Immunohistochemistry in Differential Diagnosis of Ewing Sarcoma., PMID:40230184
Targeting friend leukemia integration 1: A promising approach for prevention and treatment of solid tumors., PMID:40228766
Druggable upregulated proteins in EWS-FLI-driven Ewing sarcoma as emerging new therapeutic targets., PMID:40225989
(GGAA)3-Based TF-PROTACs Enable Targeted Degradation of ETV6 to Inhibit Ewing Sarcoma Growth., PMID:40215343
k-mer manifold approximation and projection for visualizing DNA sequences., PMID:40210440
"Putting the cart before the horse": an update on promiscuous gene fusions in soft tissue tumors., PMID:40205020
Clinicopathologic and molecular characterization of primitive neuroectodermal tumors (PNET) in the female genital tract: a retrospective study of 8 cases., PMID:40189027
2-Hydroxy-4-n-octyloxybenzophenone induces developmental neurotoxicity and multiple sclerosis-like symptoms through cacna1a regulated Ca2 + inward flow and microglial activation., PMID:40188732
Competing dynamic gene regulatory networks involved in fibroblast reprogramming to hematopoietic progenitor cells., PMID:40185089
Characterization of a novel sarcoma cell line with an EWSR1::POU2AF3 fusion., PMID:40134582
Structure and cooperative formation of a FLI1 filament on contiguous GGAA DNA sites., PMID:40131773
FLI1 Induces Plaque Psoriasis and Its Inhibition Attenuates Disease Progression., PMID:40129872
[Clinicopathological features of primary pulmonary epithelioid hemangioendothelioma: a study of 7 cases]., PMID:40113428
Targeted inactivation of EWSR1 : : FLI1 gene in Ewing sarcoma via CRISPR/Cas9 driven by an Ewing-specific GGAA promoter., PMID:40089636
YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1-mediated reprogramming of bone mesenchymal stem cells., PMID:40080499
The zebrafish ETS transcription factor Fli1b functions upstream of Scl/Tal1 during embryonic hematopoiesis., PMID:40079219
Unveiling IRF4-steered regulation of context-dependent effector programs in CD4+ T cells under Th17- and Treg-skewing conditions., PMID:40067830
Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing., PMID:40000903
DNA methylation patterns contribute to changes of cellular differentiation pathways in leukocytes with LOY from patients with Alzheimer´s disease., PMID:39998604
Transcriptome and chromatin accessibility landscape of ovarian development at different egg-laying stages in taihe black-bone silky fowls., PMID:39922133
The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma., PMID:39894896
Pericytes mediate neuroinflammation via Fli-1 in endotoxemia and sepsis in mice., PMID:39862276
Early intervention with pericyte Fli-1 post-TBI attenuates hippocampal BBB disruption and subsequent neuroinflammation with neurological deficits., PMID:39826850
Treatment of Patients With Extraskeletal Ewing Sarcoma in the Scapular and Arm Regions With Wide Resection: A Report of Two Cases and Literature Review., PMID:39822452
Impact of Fli1 deletion on B cell populations: A focus on age-associated B cells and transcriptional dynamics., PMID:39818445
The Astragalus Membranaceus Herb Attenuates Leukemia by Inhibiting the FLI1 Oncogene and Enhancing Anti-Tumor Immunity., PMID:39769192
Ewing's sarcoma of the head and neck: differential diagnosis, treatment and outcomes., PMID:39752208
FLI1 and GATA1 govern TLN1 transcription: new insights into FLI1-related platelet disorders., PMID:39744817
Upregulation of haematopoetic cell kinase (Hck) activity by a secreted parasite effector protein (Ta9) drives proliferation of Theileria annulata-transformed leukocytes., PMID:39730099
Transcriptional regulation of KCNA2 coding Kv1.2 by EWS::FLI1: involvement in controlling the YAP/Hippo signalling pathway and cell proliferation., PMID:39695664
Comprehensive study of gene fusions in sarcomas., PMID:39680198
Transcriptome-based analysis reveals the toxic effects of perfluorononanoic acid by affecting the development of the cardiovascular system and lipid metabolism in zebrafish., PMID:39647647
Signaling pathways and targeted therapies in Ewing sarcoma., PMID:39622389
Vasculogenic skin reprogramming requires TET-mediated gene demethylation in fibroblasts for rescuing impaired perfusion in diabetes., PMID:39604331
Nature of the EWS-FLI1 Oncoprotein., PMID:39560616
Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts., PMID:39554175
Superficial Neurocristic FET::ETS Fusion Tumor: Expanding the Clinicopathological and Molecular Genetic Spectrum of a Recently Described Entity., PMID:39522640
Tissue nano-transfection of antimicrobial genes drives bacterial biofilm killing in wounds and is potentially mediated by extracellular vesicles., PMID:39491627
STAG2 loss in Ewing sarcoma alters enhancer-promoter contacts dependent and independent of EWS::FLI1., PMID:39487368
Chimeric protein EWS::FLI1 drives cell proliferation in Ewing Sarcoma via aberrant expression of KCNN1/SK1 and dysregulation of calcium signaling., PMID:39487324
Establishment and characterization of a patient-derived metastatic extraskeletal Ewing sarcoma cell line ES-ZSS-1., PMID:39475964
Chronic Low-Dose-Rate Radiation-Induced Persistent DNA Damage and miRNA/mRNA Expression Changes in Mouse Hippocampus and Blood., PMID:39451223
For research use only. Not for human or drug use.
