Catalog No.
YHF86201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp248-Asp492
Predicted molecular weight
29.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01201
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RELB, Transcription factor RelB, I-Rel
Single cell RNA-sequencing identified CCR7+/RELB+/IRF1+ T cell responding for juvenile idiopathic arthritis pathogenesis., PMID:40406113
ILC3s promote intestinal tuft cell hyperplasia and anthelmintic immunity through RANK signaling., PMID:40378237
Noradrenaline Synergistically Enhances Porphyromonas gingivalis LPS and OMV-Induced Interleukin-1β Production in BV-2 Microglia Through Differential Mechanisms., PMID:40141302
Prolyl hydroxylase domain enzymes (isoforms 1-3, PHD1-3), but not factor-inhibiting HIF-1 (FIH-1), interact with the IKK complex and attenuate LPS-activated NF-kappa-B., PMID:40024754
Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion., PMID:39992708
CD40 induces PIR-A+ macrophages to promote chronic allograft rejection., PMID:39954660
Development of RelB-targeting small-molecule inhibitors of non-canonical NF-κB signaling with antitumor efficacy., PMID:39910816
Endothelial TRIM35-Regulated MMP10 Release Exacerbates Calcification of Vascular Grafts., PMID:39865905
The cryptic lncRNA-encoded microprotein TPM3P9 drives oncogenic RNA splicing and tumorigenesis., PMID:39865075
Trichinella spiralis extracellular vesicles induce anti-inflammatory and regulatory immune responses in vitro., PMID:39842685
Clinicopathological and Prognostic Significance of Tim-3 and Rel-B Expressions in Grade 4 Diffuse Gliomas., PMID:39840558
Polyphenol Profile and Antioxidant, Antityrosinase, and Anti-Melanogenesis Activities of Ethanol Extract of Bee Pollen., PMID:39770476
Gram-negative bacteria-driven increase of cytosolic phospholipase A2 leads to activation of Kupffer cells., PMID:39725773
Influence of head and neck cancer exosomes on macrophage polarization., PMID:39700664
The microRNA-29ab1/Zfp36/AR Axis in the Hypothalamus Regulates Male-Typical Behaviors in Mice., PMID:39684798
Systems biology-enabled targeting of NF-κΒ and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL., PMID:39677808
TIFAB modulates metabolic pathways in KMT2A::MLLT3-induced AML through HNF4A., PMID:39626355
Exosome-like nanoparticles from Arbutus unedo L. mitigate LPS-induced inflammation via JAK-STAT inactivation., PMID:39474636
[NF-κB transcription factors regulate the expression of immunity-related genes in different cell lines of silkworm (Bombyx mori)]., PMID:39467756
Dominant immune tolerance in the intestinal tract imposed by RelB-dependent migratory dendritic cells regulates protective type 2 immunity., PMID:39443450
Insight into prostate cancer osteolytic metastasis by RelB coordination of IL-8 and S100A4., PMID:39415352
RelB and C/EBPα critically regulate the development of Peyer's patch mononuclear phagocytes., PMID:39413971
Biophysical characterization of RelA-p52 NF-κB dimer-A link between the canonical and the non-canonical NF-κB pathway., PMID:39412374
Polyenylphosphatidylcholine alleviates cardiorenal fibrosis, injury and dysfunction in spontaneously hypertensive rats by regulating Plpp3 signaling., PMID:39403590
EZH2 functional dichotomy in reactive oxygen species-stratified glioblastoma., PMID:39373211
NF-κB Transcription Factors: Their Distribution, Family Expansion, Structural Conservation, and Evolution in Animals., PMID:39337282
Inherited human RelB deficiency impairs innate and adaptive immunity to infection., PMID:39231201
RANKL/RANK contributes to the pathological process of type 2 diabetes mellitus through TRAF3 activation of NIK., PMID:39217877
Lymphotoxin beta-activated LTBR/NIK/RELB axis drives proliferation in cholangiocarcinoma., PMID:39164890
DDX5 deficiency drives non-canonical NF-κB activation and NRF2 expression, influencing sorafenib response and hepatocellular carcinoma progression., PMID:39122708
PUM1-TRAF3 fusion protein activates non-canonical NF-κB signaling via rescued NIK in biliary tract cancer., PMID:39090283
B cells expressing mutated IGHV1-69-encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection., PMID:39082968
Non-canonical NF-κB signaling limits the tolerogenic β-catenin-Raldh2 axis in gut dendritic cells to exacerbate intestinal pathologies., PMID:39060515
Disseminated tuberculosis is associated with impaired T cell immunity mediated by non-canonical NF-κB pathway., PMID:39032519
LTβR-RelB signaling in intestinal epithelial cells protects from chemotherapy-induced mucosal damage., PMID:38873613
MALT1 substrate cleavage: what is it good for?, PMID:38863711
cFLIP in the molecular regulation of astroglia-driven neuroinflammation in experimental glaucoma., PMID:38824526
Decidual natural killer cells dysfunction is caused by IDO downregulation in dMDSCs with Toxoplasma gondii infection., PMID:38822095
β-D-Glucan promotes NF-κB activation and ameliorates high-LET carbon-ion irradiation-induced human umbilical vein endothelial cell injury., PMID:38813508
Effects of Berberine on Lipid Metabolism, Antioxidant Status, and Immune Response in Liver of Tilapia (Oreochromis niloticus) under a High-Fat Diet Feeding., PMID:38790653
The glycolytic enzyme PFKFB3 drives kidney fibrosis through promoting histone lactylation-mediated NF-κB family activation., PMID:38789037
TET1 mediated m5C modification of RelB aggravates cerebral ischemia/reperfusion-induced neuroinflammation through regulating microglia polarization., PMID:38705503
Identification of common genes and pathways between type 2 diabetes and COVID-19., PMID:38699234
Omental Preadipocytes Stimulate Matrix Remodeling and IGF Signaling to Support Ovarian Cancer Metastasis., PMID:38635891
The noncanonical NFκB pathway: Regulatory mechanisms in health and disease., PMID:38634218
Adipose-derived stem cell modulate tolerogenic dendritic cell-induced T cell regulation is correlated with activation of Notch-NFκB signaling., PMID:38625070
The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia., PMID:38608702
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages., PMID:38594444
Induction of the human CDC45 gene promoter activity by natural compound trans‑resveratrol., PMID:38577929
Multi-omics reveals that 5-O-methylvisammioside prevention acute liver injury in mice by regulating the TNF/MAPK/NF-κB/arachidonic acid pathway., PMID:38522313
For research use only. Not for human or drug use.
