Catalog No.
YHF78701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp858-Leu1184
Predicted molecular weight
38.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P98095
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FBLN2, Fibulin-2, FIBL-2
Alternative Splicing of FBLN2 Generates a Prometastatic Extracellular Matrix in Gastrointestinal Cancers by Determining N-Glycosylation of Fibulin 2., PMID:40400104
Redox Mechanisms Driving Skin Fibroblast-to-Myofibroblast Differentiation., PMID:40298862
Proteomic analysis of liver fibrosis reveals EFEMP1 as a new modulator of focal adhesion and migration of hepatic stellate cells., PMID:40171970
FBLN2 inhibits gastric cancer proliferation and metastasis via the TGFβ/TGIF2 pathway., PMID:40168772
CircFBLN2 regulates duck myoblast proliferation and differentiation through miR-22-5p and MEF2C interaction., PMID:40120247
Targeting extracellular matrix components to attenuate microglia neuroinflammation: A study of fibulin-2 and CSPGs in a model of multiple sclerosis., PMID:39864280
Identification of novel cytoskeleton protein involved in spermatogenic cells and sertoli cells of non-obstructive azoospermia based on microarray and bioinformatics analysis., PMID:39863862
The Proteomic Landscape of the Coronary Accessible Heart Cell Surfaceome., PMID:39790063
Single-cell transcriptomic analysis and luteolin treatment reveal three adipogenic genes, including Aspn, Htra1 and Efemp1., PMID:39662603
Circ_0001944 Targets the miR-1292-5p/FBLN2 Axis to Facilitate Sorafenib Resistance in Hepatocellular Carcinoma by Impeding Ferroptosis., PMID:39624827
Prognostic value of EMT-related genes and immune cell infiltration in thyroid carcinoma., PMID:39559351
C2C12 myoblasts differentiate into myofibroblasts via the TGF-β1 signaling pathway mediated by Fibulin2., PMID:39490650
Metabolic and Proteomic Profiling of Coronary Microvascular Dysfunction: Insights from Rat Models., PMID:39456238
Fibroblast-specific TGF-β signaling mediates cardiac dysfunction, fibrosis, and hypertrophy in obese diabetic mice., PMID:39373248
Identification of Gene Signatures Associated with COVID-19 across Children, Adolescents, and Adults in the Nasopharynx and Peripheral Blood by Using a Machine Learning Approach., PMID:39350407
Transcriptomic Differences by RNA Sequencing for Evaluation of New Method for Long-Time In Vitro Culture of Cryopreserved Testicular Tissue for Oncologic Patients., PMID:39329723
Modeling the profibrotic microenvironment in vitro: Model validation., PMID:39208646
The Prognostic Role of Fibulin-2 and Ki-67 Index in Patients with Meningioma: A Study among Minangkabau Ethnicity., PMID:39205571
FBLN2 is associated with basal cell markers Krt14 and ITGB1 in mouse mammary epithelial cells and has a preferential expression in molecular subtypes of human breast cancer., PMID:39110274
FBLN2 is associated with Goldenhar syndrome and is essential for cranial neural crest cell development., PMID:38970771
Biophysical and structural studies of fibulin-2., PMID:38956220
The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease., PMID:38915286
Identification of Regulatory RNA-Binding Proteins Associated with Immune Infiltration in Laryngeal Squamous Cell Carcinoma., PMID:38912837
Fibulin-2 is an extracellular matrix inhibitor of oligodendrocytes relevant to multiple sclerosis., PMID:38743490
Lung Inflammatory Phenotype in Mice Deficient in Fibulin-2 and ADAMTS-12., PMID:38396702
ITGBL1 promotes anoikis resistance and metastasis in human gastric cancer via the AKT/FBLN2 axis., PMID:38332530
Analysis of joint protein expression profile in anterior disc displacement of TMJ with or without OA., PMID:38251222
Identification of key genes and regulatory networks involved in the Comorbidity of atrial fibrillation and chronic obstructive pulmonary disease., PMID:39811093
Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function., PMID:37929635
Genome-wide analysis revealed the dysregulation of RNA binding protein-correlated alternative splicing events in myocardial ischemia reperfusion injury., PMID:37858115
TMT-based quantitative proteomic analysis revealed that FBLN2 and NPR3 are involved in the early osteogenic differentiation of mesenchymal stem cells (MSCs)., PMID:37543430
Hypoxia-based classification and prognostic signature for clinical management of hepatocellular carcinoma., PMID:37481543
Defining the clinical validity of genes reported to cause pulmonary arterial hypertension., PMID:37422716
Luteolin Alleviates Liver Fibrosis in Rat Hepatic Stellate Cell HSC-T6: A Proteomic Analysis., PMID:37360572
Fibulin-2: A potential regulator of immune dysfunction after bone trauma., PMID:37249292
Fibulin-2 Facilitates Malignant Progression of Hepatocellular Carcinoma., PMID:37162505
Age-associated differences in the human lung extracellular matrix., PMID:37039368
Targeted O-glycoproteomics for the development of diagnostic markers for advanced colorectal cancer., PMID:36845686
The Effect of the Histone Chaperones HSPA8 and DEK on Tumor Immunity in Hepatocellular Carcinoma., PMID:36768989
Knockdown of FBLN2 suppresses TGF-β1-induced MRC-5 cell migration and fibrosis by downregulating VTN., PMID:36608640
Profound Effects of Dexamethasone on the Immunological State, Synthesis and Secretion Capacity of Human Testicular Peritubular Cells., PMID:36231125
Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis., PMID:36181700
Whole Exome Sequencing of Patients With Heritable and Idiopathic Pulmonary Arterial Hypertension in Central Taiwan., PMID:35811711
Integrative analysis of the DNA methylome and transcriptome in uterine leiomyoma shows altered regulation of genes involved in metabolism, proliferation, extracellular matrix, and vesicles., PMID:35472162
A Novel Quantification System Combining iTRAQ Technology and Multi-Omics Assessment to Predict Prognosis and Immunotherapy Efficacy in Colon Cancer., PMID:35445008
A Clinical Diagnostic Study: Fibulin-2 is a Novel Promising Biomarker for Predicting Infection., PMID:35303288
Ultraviolet radiation-induced degradation of dermal extracellular matrix and protection by green tea catechins: a randomized controlled trial., PMID:35279873
Extracellular Matrix Derived From Dental Pulp Stem Cells Promotes Mineralization., PMID:35155398
The Role of the Stromal Extracellular Matrix in the Development of Pterygium Pathology: An Update., PMID:34945227
Fibulin 2 Is Hypermethylated and Suppresses Tumor Cell Proliferation through Inhibition of Cell Adhesion and Extracellular Matrix Genes in Non-Small Cell Lung Cancer., PMID:34769264
For research use only. Not for human or drug use.
