Catalog No.
YHF72301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly23-Lys67
Predicted molecular weight
7.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P81534
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DEFB103, BD-3, Defensin, beta 103, BD3, Beta-defensin 3, Defensin-like protein, DEFB103A, hBD-3, HBD3, DEFB3, Beta-defensin 103, DEFB-3
[ROLE OF ANTIMICROBIAL/HOST DEFENSE PEPTIDES ON SKIN BARRIER FUNCTION AND ACTIVATION OF AUTOPHAGY IN ATOPIC DERMATITIS]., PMID:40500191
Anti-virulence and anti-efflux pump activity of synthetic defensins and histatin in Candida auris., PMID:40306590
Design of a multi-epitope vaccine against Staphylococcus Aureus lukotoxin ED using in silico approaches., PMID:40280948
Distinct anti-microbial peptides expression patterns and microbiome profiles in skin of Tunisian endemic Pemphigus foliaceus patients., PMID:40009223
Staphylococcus epidermidis augments human β-defensin-3 synthesis through the transforming growth factor alpha-epidermal growth factor receptor cascade., PMID:39306536
Human beta defensin 3 knockdown inhibits the proliferation and migration of airway smooth muscle cells through regulating the PI3K/AKT signaling pathway., PMID:38422885
Identification of putative orthologs of clinically relevant antimicrobial peptides in the equine ocular surface and amniotic membrane., PMID:36478371
Integrated analysis of lncRNAs and mRNAs by RNA-Seq in secondary hair follicle development and cycling (anagen, catagen and telogen) of Jiangnan cashmere goat (Capra hircus)., PMID:35524260
Cervicovaginal levels of human beta defensins during bacterial vaginosis., PMID:34855866
Experimental and simulation studies reveal mechanism of action of human defensin derivatives., PMID:34838874
A novel smaller β-defensin-derived peptide is active against multidrug-resistant bacterial strains., PMID:34818435
Inactivation of HIV-1 in Polarized Infant Tonsil Epithelial Cells by Human Beta-Defensins 2 and 3 Tagged with the Protein Transduction Domain of HIV-1 Tat., PMID:34696473
The Antimicrobial Peptide Human β-Defensin-3 Accelerates Wound Healing by Promoting Angiogenesis, Cell Migration, and Proliferation Through the FGFR/JAK2/STAT3 Signaling Pathway., PMID:34594328
Interaction of Human β Defensin Type 3 (hBD-3) with Different PIP2-Containing Membranes, a Molecular Dynamics Simulation Study., PMID:34473496
Binding free energy calculation of human beta defensin 3 with negatively charged lipid bilayer using free energy perturbation method., PMID:34399250
Human beta defensin levels and vaginal microbiome composition in post-menopausal women diagnosed with lichen sclerosus., PMID:34362937
Engineering and characterization of human β-defensin-3 and its analogues and microcin J25 peptides against Mannheimia haemolytica and bovine neutrophils., PMID:34112244
Identification of a crocodylian β-defensin variant from Alligator mississippiensis with antimicrobial and antibiofilm activity., PMID:33865931
Steroid hormone modulates the production of cathelicidin and human β-defensins in lung epithelial cells and macrophages promoting Mycobacterium tuberculosis killing., PMID:33799143
Significance of the chemokine CXCL10 and human beta-defensin-3 as biomarkers of pulmonary tuberculosis., PMID:33773403
Nicotine promotes the intracellular growth of Mycobacterium tuberculosis in epithelial cells., PMID:33262029
Antimicrobial peptide gene expression in medication-related osteonecrosis of the jaw., PMID:33065485
Dithranol targets keratinocytes, their crosstalk with neutrophils and inhibits the IL-36 inflammatory loop in psoriasis., PMID:32484435
Topical Estrogen Treatment Augments the Vaginal Response to Escherichia coli Flagellin., PMID:32439855
Human β-defensin 3 gene modification promotes the osteogenic differentiation of human periodontal ligament cells and bone repair in periodontitis., PMID:32350241
The Inhibitory Effect of Human Beta-defensin-3 on Candida Glabrata Isolated from Patients with Candidiasis., PMID:32316784
Cervical Gene Delivery of the Antimicrobial Peptide, Human β-Defensin (HBD)-3, in a Mouse Model of Ascending Infection-Related Preterm Birth., PMID:32117260
Skin of atopic dermatitis patients shows disturbed β-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition., PMID:32092464
Human β-defensin-3 reduces excessive autophagy in intestinal epithelial cells and in experimental necrotizing enterocolitis., PMID:31882811
Synthetic Human β Defensin-3-C15 Peptide in Endodontics: Potential Therapeutic Agent in Streptococcus gordonii Lipoprotein-Stimulated Human Dental Pulp-Derived Cells., PMID:31861863
Evidence that changes in antimicrobial peptides during tuberculosis are related to disease severity, clinical presentation, specific therapy and levels of immune-endocrine mediators., PMID:31731048
Integrated solid-state NMR and molecular dynamics modeling determines membrane insertion of human β-defensin analog., PMID:31701030
Beta-defensins and analogs in Helicobacter pylori infections: mRNA expression levels, DNA methylation, and antibacterial activity., PMID:31537016
Bifonazole Exerts Anti-Inflammatory Effects in Human Three-Dimensional Skin Equivalents after UVB or Histamine Challenge., PMID:31509851
Permeation of beta-defensin-3 encapsulated with polyethylene glycol in lung surfactant models at air-water interface., PMID:31351272
Future trends in the treatment of atopic dermatitis., PMID:31204894
BD-2 and BD-3 increase skin flap survival in a model of ischemia and Pseudomonas aeruginosa infection., PMID:31133641
Effect of analogues of cationic peptides on dentin mineralization markers in odontoblast-like cells., PMID:31112936
Microbiological characterisation of the colonisation by Candida sp in patients with orthodontic fixed appliances and evaluation of host responses in saliva., PMID:30561858
Decreased progranulin expression in Mycosis fungoides: a possible association with the high frequency of skin infections., PMID:30530405
Translocation of Human β Defensin Type 3 through a Neutrally Charged Lipid Membrane: A Free Energy Study., PMID:30431279
Multi-species oral biofilm promotes reconstructed human gingiva epithelial barrier function., PMID:30375445
Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3., PMID:30275324
Modification of the surface of titanium with multifunctional chimeric peptides to prevent biofilm formation via inhibition of initial colonizers., PMID:30254440
Antibacterial properties of human beta defensin-3 derivative: CHRG01., PMID:30207316
Induction and antiviral activity of human β-defensin 3 in intestinal cells with picornavirus infection., PMID:30160144
Pharmacological characterization of human beta-defensins 3 and 4 on potassium channels: Evidence of diversity in beta-defensin-potassium channel interactions., PMID:30121363
Reciprocal role of hBD2 and hBD3 on the adaptive immune response by measuring T lymphocyte proliferation in terms of CD4 and CCR6 expression., PMID:30098283
Langerhans cells express human β-defensin 3: relevance for immunity during skin ageing., PMID:29758092
Multi-Center, Double-Blind, Vehicle-Controlled Clinical Trial of an Alpha and Beta Defensin-Containing Anti-Aging Skin Care Regimen With Clinical, Histopathologic, Immunohistochemical, Photographic, and Ultrasound Evaluation., PMID:29601620
For research use only. Not for human or drug use.
