Catalog No.
YHF71901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser25-Thr84
Predicted molecular weight
9.25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P81172
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Putative liver tumor regressor, HEPC, LEAP-1, Liver-expressed antimicrobial peptide 1, PLTR, Hepcidin, LEAP1, Hepc25, Hepc20, HAMP
In Silico Analysis and Molecular Docking of Human Antimicrobial Peptides for Targeting Monkeypox Virus: Potential Therapeutic Implications of Histatin 5 Peptide., PMID:40351068
Diminishing Hepcidin via Reducing IL-6/STAT3 Pathway by Utilizing Ferulic Acid: An In Vitro Study., PMID:40299525
Di-HAMP domains of a cytoplasmic chemoreceptor modulate nucleoid array formation and downstream signaling., PMID:40249191
A detailed transcriptome study uncovers the epigenetic characteristics associated with Aromatase inhibitor-induced masculinization in Takifugu rubripes larvae gonads., PMID:40240894
Structural Insight Into the Conversion of DhNik1, A Hybrid Histidine Kinase From Debaryomyces hansenii to a Cytotoxic Phosphatase Conformation for Novel Antifungal Agent., PMID:40174667
An Insect Salivary Sheath Protein Triggers Plant Resistance to Insects and Pathogens as a Conserved HAMP., PMID:40167256
Insertion sequences in mgrB and mutations in two-component system genes confer high polymyxin resistance to carbapenem-resistant Enterobacter cloacae complex strains., PMID:40165791
HFE-Related Hemochromatosis May Be a Primary Kupffer Cell Disease., PMID:40149659
Ginsenoside Rb1 and berberine synergistically protect against type 2 diabetes mellitus via GDF15/HAMP pathway throughout the liver lobules: Insights from spatial transcriptomics analysis., PMID:40147680
Deletion of hepcidin disrupts iron homeostasis and hematopoiesis in zebrafish embryogenesis., PMID:40110772
Hepcidin knockout exacerbates hindlimb unloading-induced bone loss in mice through inhibiting osteoblastic differentiation., PMID:40102891
Insights Into the Conformational Dynamics of the Cytoplasmic Domain of Metal-Sensing Sensor Histidine Kinase ZraS., PMID:40062583
Link between iron-mediated lipid peroxidation and polycystic ovary syndrome (PCOS): exploring the genes underlying iron regulatory mechanism., PMID:40057801
Hepcidin peptide controls the inflammatory response induced by betanodavirus infection and improves European sea bass (Dicentrachus labrax) survival., PMID:40027333
Novel point mutations M402V, M541I in the HAMP domain and L915M in the HATPase_c domain of FgOs1 confer differential resistance to fludioxonil in Fusarium graminearum., PMID:39986532
Quercetin alleviates LPS/iE-DAP-induced liver injury by suppressing ferroptosis via regulating ferritinophagy and intracellular iron efflux., PMID:39986118
Analysis of Striped Bass (Morone saxatilis) and White Bass (M. chrysops) Splenic Transcriptome Following Streptococcus iniae Infection., PMID:39961922
The serum hepcidin and the hepcidin/ferritin ratio in NAFLD: a systematic review and meta-analysis., PMID:39915727
Iron metabolism in a mouse model of hepatocellular carcinoma., PMID:39820815
Hepcidin inhibits hepatocyte apoptosis through the PERK pathway in acute liver injury and fibrosis., PMID:39699302
Effect of dietary protein on serum hepcidin and iron in adults with obesity and insulin resistance: A randomized single blind clinical trial., PMID:39674725
Unravelling the ontogeny and tissue-specific expression profiles of immune-related genes in the near-threatened endemic catfish, Clarias dussumieri., PMID:39642945
BMP10 Knockdown Modulates Endothelial Cell Immunoreactivity by Inhibiting the HIF-1α Pathway in the Sepsis-Induced Myocardial Injury., PMID:39611400
Chitin-signaling-dependent responses to insect oral secretions in rice cells propose the involvement of chitooligosaccharides in plant defense against herbivores., PMID:39579336
RAS signaling pathway is essential in regulating PIEZO1-mediated hepatic iron overload in dehydrated hereditary stomatocytosis., PMID:39558179
Effects of iron overload in human joint tissue explant cultures and animal models., PMID:39531048
Hepcidin expression is associated with increased γ-secretase-mediated cleavage of neogenin in the liver., PMID:39454953
Determining the expression of vitamin D receptor, regulator of iron metabolism hepcidin and cathelicidin antimicrobial peptide genes for development of future diagnostic and therapeutic options in patients with inflammatory bowel disease., PMID:39415526
Enzyme replacement therapy improves erythropoiesis and iron dysregulation in Gaucher disease., PMID:39370488
Multiomic profiling identifies predictors of survival in African American patients with acute myeloid leukemia., PMID:39367245
What does the FOX(O) say? High iron: hepcidin!, PMID:39298162
P. Gingivalis induce macrophage polarization by regulating hepcidin expression in chronic apical periodontitis., PMID:39278061
A conserved protein family in mirid bug Riptortus pedestris plays dual roles in regulating plant immunity., PMID:39230888
Elevated plasma hepcidin concentrations are associated with an increased risk of mortality and nonfatal cardiovascular events in patients with type 2 diabetes: a prospective study., PMID:39154180
Investigating the Hepcidin Gene Polymorphisms in COVID-19-Associated Mucormycosis Susceptibility: A Clinical-Laboratory Study., PMID:39114634
Iron Overloading Potentiates the Antitumor Activity of 5-Fluorouracil by Promoting Apoptosis and Ferroptosis in Colorectal Cancer Cells., PMID:39097854
Alisma Orientalis Extract Ameliorates Hepatic Iron Deregulation in MAFLD Mice via FXR-Mediated Gene Repression., PMID:39064715
High Glucose Increases Lactate and Induces the Transforming Growth Factor Beta-Smad 1/5 Atherogenic Pathway in Primary Human Macrophages., PMID:39062148
Hereditary haemochromatosis: Prevalence and characterization of the disease in a tertiary hospital in Aragon, Spain., PMID:39003111
The potential significance of hepcidin evaluation in progressive supranuclear palsy., PMID:38953731
Ribonuclease inhibitor 1 emerges as a potential biomarker and modulates inflammation and iron homeostasis in sepsis., PMID:38951571
Molecular characterization of HAMP rs10421768 gene and phenotypic expression of hepcidin; a case-control study among sickle cell anaemia patients in Ghana., PMID:38935685
Secret Weapon of Insects: The Oral Secretion Cocktail and Its Modulation of Host Immunity., PMID:38877965
How sensor Amt-like proteins integrate ammonium signals., PMID:38838143
SUGP2 p.(Arg639Gln) variant is involved in the pathogenesis of hemochromatosis via the CIRBP/BMPER signaling pathway., PMID:38800953
HAMP predicts a pivotal role in modulating the malignant behaviors of non-small cell lung cancer cells., PMID:38787358
Identification of the molecular subtypes and signatures to predict the prognosis, biological functions, and therapeutic response based on the anoikis-related genes in colorectal cancer., PMID:38785271
Investigation of BMP6 mutations in Brazilian patients with iron overload., PMID:38719717
Identification of urine biomarkers of endometriosis-Protein mass spectrometry., PMID:38709906
Rocaglamide regulates iron homeostasis by suppressing hepcidin expression., PMID:38657753
For research use only. Not for human or drug use.
