Catalog No.
YHF71501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro249-Lys500
Predicted molecular weight
31.03 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P80404
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Gamma-amino-N-butyrate transaminase, GABA transaminase, (S)-3-amino-2-methylpropionate transaminase, GABA aminotransferase, L-AIBAT, GABA-T, ABAT, 4-aminobutyrate aminotransferase, mitochondrial, GABA-AT, GABAT
Biochemical investigation of pathogenic missense mutations of human 4-amino butyrate aminotransferase towards the understanding of the molecular pathogenesis of GABA transaminase deficiency., PMID:40414180
Biomarker-driven drug repurposing for NAFLD-associated hepatocellular carcinoma using machine learning integrated ensemble feature selection., PMID:40313868
Development of a prognostic model based on the ceRNA network in Triple-Negative Breast cancer., PMID:40034665
GABA regulates metabolic reprogramming to mediate the development of brain metastasis in non-small cell lung cancer., PMID:39972344
Biological Basis of Cell Trafficking: A General Overview., PMID:39756816
Overcoming GABA-Induced Treg Suppression of Immunity by ABAT to Augment CD8+T Cell Antitumor Immune Response in Liver Cancer., PMID:39586256
Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shifts., PMID:39100925
Dupilumab treatment in paediatric atopic dermatitis (2-18 years): Spanish multicentre retrospective real-world study., PMID:39093288
Integrative Meta-Analysis: Unveiling Genetic Factors in Meat Sheep Growth and Muscular Development through QTL and Transcriptome Studies., PMID:38891726
Physiological and transcriptomic analysis provides new insights into osmoregulation mechanism of Ruditapes philippinarum under low and high salinity stress., PMID:38750748
PMBC: a manually curated database for prognostic markers of breast cancer., PMID:38748636
The function of brown adipose tissue at different sites of the body in Brandt's voles during cold acclimation., PMID:38723743
Transcriptomic and proteomic fingerprints induced by the fungicides difenoconazole and metalaxyl in zebrafish embryos., PMID:38135202
Comparative proteomic analysis of cerebral cortex revealed neuroprotective mechanism of esculentoside A on Alzheimer's disease., PMID:38128868
Tumor-Promoting Effects of Microrna-421/4-Aminobutyrate Aminotransferase Axis in Hepatocellular Carcinoma., PMID:37918014
Mitochondrial subtype MB-G3 contains potential novel biomarkers and therapeutic targets associated with prognosis of medulloblastoma., PMID:37886818
Xihuang pill ameliorates colitis in mice by improving mucosal barrier injury and inhibiting inflammatory cell filtration through network regulation., PMID:37640256
Clinical Utility of SARS-CoV-2 Antibody Titer Multiplied by Binding Avidity of Receptor-Binding Domain (RBD) in Monitoring Protective Immunity and Clinical Severity., PMID:37632005
The ketogenic diet promotes triacylglycerol recycling in white adipose tissue and uncoupled fat oxidation in brown adipose tissue, but does not reduce adiposity in rats., PMID:37422170
The impact of RNA binding proteins and the associated long non-coding RNAs in the TCA cycle on cancer pathogenesis., PMID:37221841
Differential effects of dopamine receptor agonists ropinirole and quinpirole on locomotor and anxiolytic behaviors in larval zebrafish (Danio rerio): A role for the GABAergic and glutamate system?, PMID:37211288
Assessing adipokines as potential biomarkers of dementia, Alzheimer's disease, and mild cognitive impairment: A systematic review and meta-analysis., PMID:37165483
A crucial exosome-related gene pair (AAMP and ABAT) is associated with inflammatory cells in intervertebral disc degeneration., PMID:37122729
Identification of the regulatory mechanism of ACE2 in COVID-19-induced kidney damage with systems genetics approach., PMID:36951969
["Component-target-efficacy" network analysis and experimental verification of Qingkailing Oral Preparation]., PMID:36725269
Effects of UGT1A, CYP2C9/19 and ABAT polymorphisms on plasma concentration of valproic acid in Chinese epilepsy patients., PMID:36718958
Epigenetic dysregulation of articular cartilage during progression of hip femoroacetabular impingement disease., PMID:36606425
GAB functions as a bioenergetic and signalling gatekeeper to control T cell inflammation., PMID:36192601
Genetic variations in GABA metabolism and epilepsy., PMID:35850019
miR-15a regulates the preadipocyte differentiation by targeting ABAT gene in Yanbian yellow cattle., PMID:35732048
Association of Glyphosate Exposure with Blood DNA Methylation in a Cross-Sectional Study of Postmenopausal Women., PMID:35377194
Gamma-Aminobutyrate Transaminase Protects against Lipid Overload-Triggered Cardiac Injury in Mice., PMID:35216295
Total withanolides ameliorates imiquimod-induced psoriasis-like skin inflammation., PMID:34875348
Novel Branched-Chain Amino Acid-Catabolism Related Gene Signature for Overall Survival Prediction of Pancreatic Carcinoma., PMID:34816714
ABAT targeted by miR-183-5p regulates cell functions in liver cancer., PMID:34742920
Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination., PMID:34192534
In silico analysis of differentially expressed genesets in metastatic breast cancer identifies potential prognostic biomarkers., PMID:34172056
EARN: an ensemble machine learning algorithm to predict driver genes in metastatic breast cancer., PMID:33962648
Identification of metabolism genes related to hepatocarcinogenesis and progression in type 2 diabetes mellitus via co-expression networks analysis., PMID:33865459
Development and Molecular Investigation into the Effects of Carbamazepine Exposure in the Zebrafish (Danio rerio)., PMID:33260372
A Targeted Bioinformatics Assessment of Adrenocortical Carcinoma Reveals Prognostic Implications of GABA System Gene Expression., PMID:33187258
Polypill with or without Aspirin in Persons without Cardiovascular Disease., PMID:33186492
Identification of Hub Genes Associated With Hepatocellular Carcinoma Using Robust Rank Aggregation Combined With Weighted Gene Co-expression Network Analysis., PMID:33133125
Genetic markers for treatment-related pancreatitis in a cohort of Hispanic children with acute lymphoblastic leukemia., PMID:32447501
ABAT and ALDH6A1, regulated by transcription factor HNF4A, suppress tumorigenic capability in clear cell renal cell carcinoma., PMID:32093682
Comprehensive Analysis of the Characteristics and Differences in Adult and Newborn Brown Adipose Tissue (BAT): Newborn BAT Is a More Active/Dynamic BAT., PMID:31947603
Inhibition of 4-aminobutyrate aminotransferase protects against injury-induced osteoarthritis in mice., PMID:31534049
Role of 4‑aminobutyrate aminotransferase (ABAT) and the lncRNA co‑expression network in the development of myelodysplastic syndrome., PMID:31173260
Dual Role of Bile Acids on the Biliary Epithelium: Friend or Foe?, PMID:31014010
Loss of ABAT-Mediated GABAergic System Promotes Basal-Like Breast Cancer Progression by Activating Ca2+-NFAT1 Axis., PMID:30662552
For research use only. Not for human or drug use.
