Catalog No.
YHF71201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val25-Asp104
Predicted molecular weight
11.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P80303
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NEFA, Gastric cancer antigen Zg4, Prepronesfatin, NUCB2, DNA-binding protein NEFA, Nucleobindin-2, Epididymis secretory protein Li 109
Nesfatin-1 Suppresses Inflammation in Bronchopulmonary Dysplasia by Regulating HMGB-1/TLR4/p65/NLRP3 Signaling Pathway., PMID:40415368
Acute effects of peripherally administered nicotine on food intake via the central anorectic peptide nesfatin-1/nucleobindin-2 in adult male rats., PMID:40368052
"Satiety molecules" - nesfatin-1 and glucagon-like peptide 1 in blood serum in patients with anorexia nervosa and obesity., PMID:40331844
Psilocybin and ketamine affect novel neuropeptides gene expression in the rat hypothalamus., PMID:40243003
Obesity Parameters in Women Is Associated With AMY1 Gene Copy Number, Nesfatin-1 Level, and Dietary Intake: A Case-Control Study., PMID:40190144
The anorexigenic peptide nesfatin-1 dampens the B cell response to receptor-mediated stimulation through inhibition of NF-κB signaling., PMID:40135734
Association among nesfatin-1, obesity category, presence of obesity-related complications, and eating patterns in patients with obesity: Results of a single endocrine centre observational study., PMID:39921103
Adipokine Levels of RBP4, Resistin and Nesfatin-1 in Women Diagnosed With Gestational Diabetes., PMID:39903893
Nesfatin-1 Neurons in the Ventral Premammillary Nucleus Integrate Metabolic and Reproductive Signals in Male Rats., PMID:39859453
Elevated visfatin levels illuminate the inflammatory path in bronchopulmonary dysplasia., PMID:39807735
Nesfatin-1 as a crucial mediator of glucose homeostasis in the reptile, Hemidactylus flaviviridis., PMID:39738077
Transcriptomic analysis of pancreatic tissue from humans and mice identifies potential gene signatures and unexplored pathways during progression from acute to chronic pancreatitis., PMID:39732348
Nesfatin-1 is involved in hyperbaric oxygen-mediated therapeutic effects in high fat diet-induced hyperphagia in mice., PMID:39706341
The role of periostin, eosinophil cationic protein (ECP), nesfatin-1, and NUCB2 in asthma and obesity., PMID:39665477
Metabolic syndrome in association with novel dietary index, metabolic parameters, nesfatin-1 and omentin-1., PMID:39604989
Intestinal NUCB2/nesfatin-1 regulates hepatic glucose production via the MC4R-cAMP-GLP-1 pathway., PMID:39562740
Neuroanatomical mapping of spexin and nesfatin-1-expressing neurons in the human brainstem., PMID:39541873
The role of nesfatin-1 in kidney diseases., PMID:39480586
Nesfatin-1 expressed in human endometrial stromal cell line (THESC) stimulates decidualization through FAK/PI3K/AKT signaling pathway., PMID:39461478
Nesfatin-1 expression and blood plasma concentration in female dogs suffering from cystic endometrial hyperplasia and pyometra and its possible interaction with phoenixin-14., PMID:39455994
Relationship of Serum Nesfatin-1 and Insulin-Like Growth Factor-1 Levels with Adverse Pregnancy Outcomes in Patients with Polycystic Ovary Syndrome., PMID:39410683
Nesfatin-1 enhances vascular smooth muscle calcification through facilitating BMP-2 osteogenic signaling., PMID:39394127
Central NUCB2/nesfatin-1 signaling ameliorates liver steatosis through suppression of endoplasmic reticulum stress in the hypothalamus., PMID:39389418
Association between serum NUCB2/nesfatin‑1 levels and erectile dysfunction., PMID:39328399
Research progress on the relationship between Nesfatin-1 and glucose metabolism., PMID:39311778
NUCB2 promotes hepatocellular carcinoma cell growth and metastasis by activating the E2F4/PTGR1 axis., PMID:39309426
Nesfatin-1 is a regulator of inflammation with implications during obesity and metabolic syndrome., PMID:39251090
Nesfatin-1 regulates the phenotype transition of cavernous smooth muscle cells by activating PI3K/AKT/mTOR signaling pathway to improve diabetic erectile dysfunction., PMID:39226294
Nesfatin-1: A Novel Diagnostic and Prognostic Biomarker in Digestive Diseases., PMID:39200377
Peripheral nesfatin-1 reduces basal brain activity but has limited effect on epilepsy-like conditions., PMID:39140686
Nesfatin-1 inhibits cerebral aneurysms by activating Nrf2 and inhibiting NF-κB signaling., PMID:39097921
Central thromboxane A2, prostaglandin F2α, prostaglandin E, and prostaglandin D contribute to the cardiovascular effects elicited by nesfatin-1., PMID:39049997
Association of selected adipokines with vitamin D deficiency in children with inflammatory bowel disease., PMID:38961351
Nesfatin-1 ameliorates pathological abnormalities in Drosophila hTau model of Alzheimer's disease., PMID:38950494
Nesfatin-1 mitigates calcific aortic valve disease via suppressing ferroptosis mediated by GSH/GPX4 and ZIP8/SOD2 axes., PMID:38851518
Evaluating the impact of metabolic and cognitive stress on ghrelin and nesfatin-1 hormones in patients with diabetes and diabetic depression., PMID:38850208
Deciphering the dual nature of nesfatin-1: a tale of zinc ion's Janus-faced influence., PMID:38812013
Nesfatin-1 and nesfatin-1-like peptide attenuate hepatocyte lipid accumulation and nucleobindin-1 disruption modulates lipid metabolic pathways., PMID:38802487
Nucleobindin 2 inhibits senescence in gastric carcinoma., PMID:38760405
Renoprotective effect of Nesfatin-1 in Adenine-Induced Chronic kidney Disease: An in vitro and in vivo study., PMID:38750903
The Mediterranean diet, but not time-restricted eating, mediates the effects of nesfatin on beta cell function among overweight, metabolically healthy individuals., PMID:38659170
NUCB2 inhibition antagonizes osteosarcoma progression and promotes anti-tumor immunity through inactivating NUCKS1/CXCL8 axis., PMID:38636892
Neuropeptides in the rat claustrum - An immunohistochemical detection., PMID:38518508
Investigation of the Relationship of Nesfatin-1, Adropin Levels and Claudin-2, Renalase Immunoreactivity with Kidney Function in an Experimental Hypertension Model., PMID:38512760
Nesfatin-1 alleviates hyperoxia-induced bronchopulmonary dysplasia (BPD) via the nuclear factor-κB (NF-κB) p65 signaling pathway., PMID:38511245
Effects of 3.5-GHz radiofrequency radiation on energy-regulatory hormone levels in the blood and adipose tissue., PMID:38369591
Suppressive action of nesfatin-1 and nesfatin-1-like peptide on cortisol synthesis in human adrenal cortex cells., PMID:38368491
Heterotrimeric G protein signaling without GPCRs: The Gα-binding-and-activating (GBA) motif., PMID:38364891
Spexin and nesfatin-1-expressing neurons in the male human claustrum., PMID:38342331
Nuclear Binding Protein 2/Nesfatin-1 Affects Trophoblast Cell Fusion during Placental Development via the EGFR-PLCG1-CAMK4 Pathway., PMID:38339201
For research use only. Not for human or drug use.
