Catalog No.
YHF69101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val23-Ile354
Predicted molecular weight
38.39 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P78540
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Arginase-2, mitochondrial, Type II arginase, Kidney-type arginase, Arginase II, Non-hepatic arginase, ARG2
2'-Fucosyllactose Modulates the Intestinal Immune Response to Gut Microbiota and Buffers Experimental Colitis in Mice: An Integrating Investigation of Colonic Proteomics and Gut Microbiota Analysis., PMID:40501496
Screening and identification of protein interacting with goose astrovirus., PMID:40433662
Volvariella volvacea Polypeptide Mitigates Alcohol-Induced Liver Injury: A Multi-Omics Study., PMID:40361639
Deficiency of arginase2 attenuates hyperoxia-induced inflammation and airway hyperreactivity in neonatal mice., PMID:40333010
A BioID-based approach uncovers the interactome of hexose-6-phosphate dehydrogenase in breast cancer cells and identifies anterior gradient protein 2 as an interacting partner., PMID:40281598
L-arginine dependence of breast cancer - molecular subtypes matter., PMID:40140975
Mechanism of Conformational Selection of tRNAArg2 by Bacterial Deaminase TadA., PMID:40074666
The Role of the Urea Cycle in the Alzheimer's Disease Brain., PMID:40022483
SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors., PMID:39862090
Comparative proteomic analysis reveals the response mechanism of freshwater leech (Whitmania pigra) under heat-stress challenge., PMID:39729945
Arginase-II gene deficiency reduces skeletal muscle aging in mice., PMID:39670851
Striatum-enriched protein, arginase 2 localizes to medium spiny neurons and controls striatal metabolic profile., PMID:39581474
CD71+ erythroid cells promote multiple myeloma progression and impair anti-bacterial immune response., PMID:39567409
Linarin Identified as a Bioactive Compound of Lycii Cortex Ameliorates Insulin Resistance and Inflammation Through the c-FOS/ARG2 Signaling Axis., PMID:39523692
Differential Regulation of L-Arginine Metabolism through NOS2 and Arginases during Infection with Trypanosoma cruzi., PMID:39452749
HNF4A-AS1 inhibits the progression of hepatocellular carcinoma by promoting the ubiquitin-modulated degradation of PCBP2 and suppressing the stability of ARG2 mRNA., PMID:39430249
Lactate-upregulated ARG2 expression induces cellular senescence in fibroblast-like synoviocytes of osteoarthritis via activating the mTOR/S6K1 signaling pathway., PMID:39236462
Arginine-loaded globular BSAMA/fibrous GelMA biohybrid cryogels with multifunctional features and enhanced healing for soft gingival tissue regeneration., PMID:39179087
Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism., PMID:39116884
ARG2 knockdown promotes G0/G1 cell cycle arrest and mitochondrial dysfunction in adenomyosis via regulation NF-κB and Wnt/Β-catenin signaling cascades., PMID:39116499
Prostaglandin D2 receptor 2 downstream signaling and modulation of type 2 innate lymphoid cells from patients with asthma., PMID:39052598
Rapid profiling of fish cell nitrogen metabolism with single-cell Raman spectroscopy: Unveiling enzyme's role in ammonia detoxification., PMID:38852346
Exploration of the Shared Gene Signatures and Molecular Mechanisms between Chronic Bronchitis and Antineutrophil Cytoplasmic Antibody-associated Glomerulonephritis: Evidence from Transcriptome Data., PMID:38847168
Arginase 2 attenuates ulcerative colitis by antioxidant effects of spermidine., PMID:38695904
Arginase 2 is a Diagnostic and Prognostic Marker for Prostate Cancer and Is Associated with Metabolism., PMID:38581330
Dietary arginine regulates the growth performance, antioxidant capacity, and immune response in Culter alburnus., PMID:38578588
Tetrandrine alleviates oxaliplatin-induced mechanical allodynia via modulation of inflammation-related genes., PMID:38419796
Construction and evaluation of endometriosis diagnostic prediction model and immune infiltration based on efferocytosis-related genes., PMID:38370978
Antagonism of regulatory ISGs enhances the anti-melanoma efficacy of STING agonists., PMID:38312842
Aging Increases Hypoxia-Induced Endothelial Permeability and Blood-Brain Barrier Dysfunction by Upregulating Arginase-II., PMID:38300641
Dermorphin [D-Arg2, Lys4] (1-4) Amide Alleviates Frostbite-Induced Pain by Regulating TRP Channel-Mediated Microglial Activation and Neuroinflammation., PMID:38277118
Peripheral mu-opioid receptor activation by dermorphin [D-Arg2, Lys4] (1-4) amide alleviates behavioral and neurobiological aberrations in rat model of chemotherapy-induced neuropathic pain., PMID:38241153
The regulatory role of eosinophils in adipose tissue depends on autophagy., PMID:38235134
Liriodendrin exerts protective effects against chronic endometritis in rats by modulating gut microbiota composition and the arginine/nitric oxide metabolic pathway., PMID:38007851
Baicalin mitigates nephropathogenic infectious bronchitis virus infection-induced spleen injury via modulation of mitophagy and macrophage polarization in Hy-Line chick., PMID:37866328
Arginase2 mediates contrast-induced acute kidney injury via facilitating nitrosative stress in tubular cells., PMID:37856999
Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush., PMID:37816735
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization., PMID:37749499
Age-related genes USP2 and ARG2 are involved in the reduction of immune cell infiltration in elderly patients with rheumatoid arthritis., PMID:37727011
Inhibition of pro-inflammatory signaling in human primary macrophages by enhancing arginase-2 via target site blockers., PMID:37701067
Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection., PMID:37572656
Liver-Inspired Polyetherketoneketone Scaffolds Simulate Regenerative Signals and Mobilize Anti-Inflammatory Reserves to Reprogram Macrophage Metabolism for Boosted Osteoporotic Osseointegration., PMID:37400369
Spermidine from arginine metabolism activates Nrf2 and inhibits kidney fibrosis., PMID:37380734
DNA Protection against Damages Induced by Low-Energy Electrons: Absolute Cross Sections for Arginine-DNA Complexes., PMID:37314381
Y-box binding protein 1 promotes chromatin accessibility to aggravate liver fibrosis., PMID:37290675
PACAP key interactions with PAC1, VPAC1, and VPAC2 identified by molecular dynamics simulations., PMID:37216328
The lncRNA OIP5-AS1/miR-4500 axis targeting ARG2 modulates oxidative stress-induced premature senescence in endothelial cells: implications for vascular aging., PMID:37203350
Macrophage-derived Osteopontin (SPP1) Protects From Nonalcoholic Steatohepatitis., PMID:37028770
Untargeted metabolomic analysis of ischemic injury in human umbilical vein endothelial cells reveals the involvement of arginine metabolism., PMID:36998018
Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy., PMID:36939275
For research use only. Not for human or drug use.
