Catalog No.
YHF66401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu81-Gln273
Predicted molecular weight
24.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P78380
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C-type lectin domain family 8 member A, LOX-1, Ox-LDL receptor 1, Lectin-like oxidized LDL receptor 1, OLR1, Oxidized low-density lipoprotein receptor 1, Lectin-like oxLDL receptor 1, LOX1, CLEC8A, hLOX-1, Lectin-type oxidized LDL receptor 1
The role of CXCL16 in atherosclerosis: from mechanisms to therapy., PMID:40491927
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-19., PMID:40397714
Exploring Renin-angiotensin System Genes as Novel Prognostic Biomarkers for Oral Squamous Cell Carcinoma., PMID:40386053
Secreted Protein Acidic and Rich in Cysteine (SPARC) Induced by the Renin-Angiotensin System Causes Endothelial Inflammation in the Early Stages of Hypertensive Vascular Injury., PMID:40362650
High metastatic tumor-derived CXCL16 mediates liver colonization metastasis by inducing Kupffer cell polarization via the PI3K/AKT/FOXO3a pathway., PMID:40347803
Establishment of fracture blister model and analysis of plasma protein markers in rats., PMID:40297588
OTUD7B controls oxLDL uptake by stabilizing Lox-1 in THP-1 and U937 cells., PMID:40294697
Oxidation of low-density lipoprotein by hemoglobin causes pulmonary microvascular endothelial barrier dysfunction through lectin-like oxidized LDL receptor 1., PMID:40249953
From Genes to Disease: Reassessing LOXHD1 and AGBL1's Contribution to Fuchs' Dystrophy., PMID:40244234
Reprogramming human macrophages in symptomatic carotid stenosis: Stabilization of atherosclerotic carotid plaques., PMID:40239267
Relaxin-2 mitigates the interaction between monocytes and endothelial cells by suppressing Egr-1., PMID:40192193
LOX-1 rewires glutamine ammonia metabolism to drive liver fibrosis., PMID:40180177
High fat-induced the upregulation of LOX-1 in RF/6A cells under high glucose condition., PMID:40168811
A Positive Feedback Loop Between CXCL16 and the Inflammatory Factors IL-17A and TGF-β Promotes Large Artery Atherosclerosis by Activating the STAT3/NF-κB Pathway., PMID:40165931
The OLR1/NF-κB feedback loop exacerbates HIV-1 Tat-induced microglial inflammatory response and neuronal apoptosis., PMID:40140148
Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex., PMID:40131218
Oxidized low-density lipoprotein induced ferroptosis in nucleus pulposus cell contributes to intervertebral disc degeneration via LOX-1/NF-κB/NOX signal., PMID:40112598
Roles of C-reactive protein and LOX-1 on cancer and myeloid-derived suppressor cells in the progression of uterine cervical cancer., PMID:40082457
Prenatal Alcohol Exposure Disrupts CXCL16 Expression in Rat Hippocampus: Temporal and Sex Differences., PMID:40076549
Selective Azapeptide CD36 Ligand MPE-298 Regulates oxLDL-LOX-1-Mediated Inflammation and Mitochondrial Oxidative Stress in Macrophages., PMID:40072113
PCSK9/LOX-1 is associated with T2DM and regulates high glucose-induced lipid metabolism dysfunction in human microvascular endothelial cells., PMID:40071808
The CXCR6-CXCL16 axis mediates T cell control of polyomavirus infection in the kidney., PMID:40043065
Exploring the relationship between serum LOX-1, Ox-LDL, and generalized anxiety disorder., PMID:40021061
Silencing of LOX-1 attenuates high glucose-induced ferroptosis in THVECs via the HIF-1α/SLC7A11 signaling pathway., PMID:40015503
Cisplatin-induced oxidative stress, apoptosis, and pro-inflammatory responses in chondrocytes through modulating LOX-1., PMID:40011998
Lectin-like oxidized low-density lipoprotein receptor-1 reduces 5-FU sensitivity in gastric cancer cells via JAK/STAT/NOX4 axis., PMID:39987658
Elevated plasma soluble lectin-like oxidised low-density lipoprotein receptor 1 as an independent prognostic biomarker in sepsis., PMID:39948564
Aspirin Improves Uterine Artery Function in Hypercholesterolemic Preeclampsia., PMID:39936305
The relationship between oxLDL, sLOX-1, PCSK9 and carotid intima-media thickness in patients with prediabetes and type 2 diabetes., PMID:39915665
Mechanistic insights into 5-aminolevulinic acid photodynamic therapy for acne vulgaris: targeting lipogenesis via the OLR1-Wnt/β-catenin pathway., PMID:39905294
Proteomics of urinary exosomes for discovering novel non-invasive biomarkers of acute myocardial infarction patients., PMID:39890005
Circulating chemokine levels and receptor polymorphisms have potential as biomarkers for fibrosis stages in patients with chronic hepatitis C infection., PMID:39825971
CXCL16 promotes proliferation of head and neck squamous cell carcinoma by regulating GPX1-mediated antioxidant levels., PMID:39815613
A comprehensive proteomic analysis reveals novel inflammatory biomarkers in intracranial aneurysms., PMID:39761748
Impact of Endurance Exercise Training on Biomarkers of Aortic Endothelial Damage in Diabetic Rats., PMID:39742025
CXCL16/CXCR6/TGF-β Feedback Loop Between M-MDSCs and Treg Inhibits Anti-Bacterial Immunity During Biofilm Infection., PMID:39716908
LOX-1-Based Assembly Layer on Devices Surface to Promote Endothelial Repair and Reduce Complications for In Situ Interventional Plaque., PMID:39692170
IGF2BP2 promotes lung adenocarcinoma progression by regulating LOX1 and tumor-associated neutrophils., PMID:39688738
Exploring the Role of Chemokine-Related Gene Deregulation and Immune Infiltration in Ischemic Stroke: Insights into CXCL16 and SEMA3E as Potential Biomarkers., PMID:39663269
Investigating intra-tumoural heterogeneity and microenvironment diversity in primary cardiac angiosarcoma through single-cell RNA sequencing., PMID:39658531
Rice bran peptides target lectin-like oxidized low-density lipoprotein receptor-1 to ameliorate atherosclerosis., PMID:39636043
Statins Combined with AAV8-TBG-LOX-1 Reduce the Vascular Lipid-driven Inflammatory Response and Inhibit Atherosclerosis., PMID:39627476
Curcumin targets CXCL16-mediated podocyte injury and lipid accumulation in diabetic kidney disease treatment., PMID:39607647
The relationship between serum levels of LOX-1, hs-cTnT, NGAL, and renal function, and their diagnostic value in patients with chronic kidney disease: a retrospective study., PMID:39604892
Serum proteomics identifies biomarkers for predicting non-survivors in elderly COVID-19 patients., PMID:39547396
Comparative analysis of Lox-1 and CD36 expression in human platelets and on circulating microparticles during ARDS-induced coagulopathy., PMID:39546984
Vegetable and Fruit Intake and LOX-Index in Japanese Municipal Workers., PMID:39477476
Therapeutic Effects of Proanthocyanidins on Diabetic Erectile Dysfunction in Rats., PMID:39456785
Modeling NK-cell lymphoma in mice reveals its cell-of-origin and microenvironmental changes and identifies therapeutic targets., PMID:39438472
Toxoplasma gondii infection induces the expression of the chemokine CXCL16 in macrophages to promote chemoattraction of CXCR6+ cells., PMID:39436058
For research use only. Not for human or drug use.
