Catalog No.
YHF60901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly86
Predicted molecular weight
11.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P63302
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
SELW, Selenoprotein W, SEPW1, SELENOW, SelW
Selenium deficiency is functionally linked with the molecular etiopathogenesis of necrotizing enterocolitis (NEC)., PMID:40459789
Selenoproteins: Zoom-In to Their Metal-Binding Properties in Neurodegenerative Diseases., PMID:39941073
RNA sequencing comparing centenarian and middle-aged women lymphoblastoid cell lines identifies age-related dysregulated expression of genes encoding selenoproteins, heat shock proteins, CD99, and BID., PMID:39445501
Impaired Upper Airway Muscle Function with Excessive or Deficient Dietary Intake of Selenium in Rats., PMID:39334739
Loss of SELENOW aggravates muscle loss with regulation of protein synthesis and the ubiquitin-proteasome system., PMID:39303039
Selenoprotein W modulates tau homeostasis in an Alzheimer's disease mouse model., PMID:39020075
[Expression Levels and Regulation of Selenoprotein Genes in Patients With Coronavirus Disease 2019]., PMID:38953254
Selenoprotein W engages in overactive osteoclast differentiation in multiple myeloma., PMID:38683225
Role of Selenoprotein W in participating in the progression of non-alcoholic fatty liver disease., PMID:38460355
Lineage tracing of T cell differentiation from T-iPSC by 2D feeder-free culture and 3D organoid culture., PMID:38162650
Selenomethionine alleviates environmental heat stress induced hepatic lipid accumulation and glycogen infiltration of broilers via maintaining mitochondrial and endoplasmic reticulum homeostasis., PMID:37797371
Matched analysis of circulating selenium with the breast cancer selenotranscriptome: a multicentre prospective study., PMID:37741974
Transcriptome analysis reveals molecular regulation mechanism of Tibet sheep tolerance to high altitude oxygen environment., PMID:37729444
Selenoproteins synergistically protect porcine skeletal muscle from oxidative damage via relieving mitochondrial dysfunction and endoplasmic reticulum stress., PMID:37270539
Selenoprotein W Ameliorates Experimental Colitis and Promotes Intestinal Epithelial Repair., PMID:37107231
The role of selenium in shaping mice brain metabolome and selenoproteome through the gut-brain axis by combining metabolomics, metallomics, gene expression, and amplicon sequencing., PMID:36958417
Both selenium deficiency and excess impair male reproductive system via inducing oxidative stress-activated PI3K/AKT-mediated apoptosis and cell proliferation signaling in testis of mice., PMID:36731804
Loss of selenoprotein W in murine macrophages alters the hierarchy of selenoprotein expression, redox tone, and mitochondrial functions during inflammation., PMID:36516721
The role of selenoproteins in neutrophils during inflammation., PMID:36336122
High-Resolution Ribosome Profiling Reveals Gene-Specific Details of UGA Re-Coding in Selenoprotein Biosynthesis., PMID:36291713
Molecular characterization and expression analysis of selenoprotein W gene in rainbow trout (Oncorhynchus mykiss) with dietary selenium levels., PMID:36261677
Comparative Proteomic Analysis Reveals the Effect of Selenoprotein W Deficiency on Oligodendrogenesis in Fear Memory., PMID:35624863
Selenoprotein Gene mRNA Expression Evaluation During Renal Ischemia-Reperfusion Injury in Rats and Ebselen Intervention Effects., PMID:35553364
Hydroxy-Selenomethionine Improves the Selenium Status and Helps to Maintain Broiler Performances under a High Stocking Density and Heat Stress Conditions through a Better Redox and Immune Response., PMID:34679677
Compensatory Protection of Thioredoxin-Deficient Cells from Etoposide-Induced Cell Death by Selenoprotein W via Interaction with 14-3-3., PMID:34638679
Selenium, as selenite, prevents adipogenesis by modulating selenoproteins gene expression and oxidative stress-related genes., PMID:34592570
Selenoproteins Protect Against Avian Liver Necrosis by Metabolizing Peroxides and Regulating Receptor Interacting Serine Threonine Kinase 1/Receptor Interacting Serine Threonine Kinase 3/Mixed Lineage Kinase Domain-Like and Mitogen-Activated Protein Kinase Signaling., PMID:34456747
Effects of Selenomethionine on Cell Viability, Selenoprotein Expression and Antioxidant Function in Porcine Mammary Epithelial Cells., PMID:34381803
Structural and biophysical characterization of the selenoprotein SelW1 from Chlamydomonas reinhardtii., PMID:34216797
Dietary selenium sources differentially regulate selenium concentration, mRNA and protein expression of representative selenoproteins in various tissues of yellow catfish Pelteobagrus fulvidraco., PMID:34085611
Selenoprotein W ensures physiological bone remodeling by preventing hyperactivity of osteoclasts., PMID:33859201
Roles of Selenoproteins in Brain Function and the Potential Mechanism of Selenium in Alzheimer's Disease., PMID:33762907
Activation of Nrf2 by Electrophiles Is Largely Independent of the Selenium Status of HepG2 Cells., PMID:33498683
Potential relationship between the selenoproteome and cancer., PMID:33133596
Copper interferes with selenoprotein synthesis and activity., PMID:33059313
Se deficiency induces renal pathological changes by regulating selenoprotein expression, disrupting redox balance, and activating inflammation., PMID:32869810
Characterization and expression analysis of seven selenoprotein genes in yellow catfish Pelteobagrus fulvidraco to dietary selenium levels., PMID:32622174
Bioactive constituents of Salvia przewalskii and the molecular mechanism of its antihypoxia effects determined using quantitative proteomics., PMID:32476549
Accessing the transcriptional status of selenoproteins in skin cancer-derived cell lines., PMID:32142958
Effect of Different Selenium Sources on Growth Performance, Tissue Selenium Content, Meat Quality, and Selenoprotein Gene Expression in Finishing Pigs., PMID:31664683
S-Glutathionylation of mouse selenoprotein W prevents oxidative stress-induced cell death by blocking the formation of an intramolecular disulfide bond., PMID:31299423
Selenoproteome Identification in Inflamed Murine Primary Bone Marrow-Derived Macrophages by Nano-LC Orbitrap Fusion Tribrid Mass Spectrometry., PMID:30972724
Identification of FAM96B as a novel selenoprotein W binding partner in the brain., PMID:30876693
PIWI-interacting RNA-36712 restrains breast cancer progression and chemoresistance by interaction with SEPW1 pseudogene SEPW1P RNA., PMID:30636640
The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration., PMID:30229511
[Effect of Sodium Selenite on Gene Expression of SELF, SELW, and TGR Selenoproteins in Adenocarcinoma Cells of the Human Prostate]., PMID:29989584
Therapeutic Targeting of the Premetastatic Stage in Human Lung-to-Brain Metastasis., PMID:29986997
Effects of dietary sodium selenite and organic selenium sources on immune and inflammatory responses and selenium deposition in growing pigs., PMID:29673733
Selenium Pretreatment Alleviated LPS-Induced Immunological Stress Via Upregulation of Several Selenoprotein Encoding Genes in Murine RAW264.7 Cells., PMID:29671252
Selenoproteins regulate stress erythroid progenitors and spleen microenvironment during stress erythropoiesis., PMID:29615406
For research use only. Not for human or drug use.
