Catalog No.
YHF56801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu394
Predicted molecular weight
47.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P63092
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GNAS1, GNAS, GSP, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Adenylate cyclase-stimulating G alpha protein
Genome-Wide Identification and Expression Analysis of Zona Pellucida (ZP) Gene Family in Cynoglossus semilaevis., PMID:40508155
GPCR-G protein signalling and its mutational landscape in cancer-Driver or passenger., PMID:40501326
[Malignant transformation of polyostotic fibrous dysplasia in long bone: a clinicopathological analysis of four cases]., PMID:40494762
Multi-locus methylation analyses reveal GNAS methylation defects in three patients with the Beckwith-Wiedemann syndrome phenotype and no molecular defects in the 11p15.5 imprinted region., PMID:40490796
Allelic expression patterns of imprinted and non-imprinted genes in cancer cell lines from multiple histologies., PMID:40414875
Characterisation of a GNAS variant linked to cortisol-producing adrenocortical adenoma., PMID:40391091
Safe Continuation of Pegvisomant During Pregnancy in a Patient With Fibrous Dysplasia/McCune-Albright Syndrome., PMID:40365550
Case Report: Late diagnosis of McCune-Albright with severe kyphoscoliosis, acromegaly and tertiary hyperparathyroidism., PMID:40357201
A Dominant Mutation in Gαs-Protein Increases Hair Pigmentation., PMID:40356280
Molecular regulation of whole genome DNA methylation in heat stress response of dairy cows., PMID:40346455
Fuling Wenxin formula treats "Qi-Yin deficiency" arrhythmia by regulating the dilated cardiomyopathy and adrenergic signaling pathway in cardiomyocytes., PMID:40319835
Non-recurrent mutations and copy number changes predominate pituitary adenoma genomes., PMID:40300997
Long-chain sulfatide enrichment is an actionable metabolic vulnerability in intraductal papillary mucinous neoplasm (IPMN)-associated pancreatic cancers., PMID:40268349
Alpha-smooth muscle actin-expressing dermal sheath cells are a major cellular contributor to heterotopic subcutaneous ossifications in a mouse model of Albright hereditary osteodystrophy., PMID:40256763
Atypical presentation of pseudohypoparathyroidism with absence of mutations in the GNAS gene: a case report., PMID:40251565
Bidirectional disruption of GNAS transcripts causes broad methylation defects in pseudohypoparathyroidism type 1B., PMID:40249781
Adrenal mixed corticomedullary tumors: report of a case with molecular characterization and systematic review., PMID:40175770
Germline-derived GNAS-Gsα variants associated with both gain-of-function and loss-of-function phenotypes., PMID:40172207
Hypocalcemic Tetany Transiently "Cured" by Pregnancy: A Case Report., PMID:40107645
An integrated multi-omics biomarker approach using molecular profiling and microRNAs for evaluation of pancreatic cyst fluid., PMID:40106268
Hepatic PKA Mediates Liver and Pancreatic α-Cell Cross Talk., PMID:40095004
Clinical spectrum and uncommon features of McCune-Albright syndrome in children: a cohort study from a National Referral Center., PMID:40078582
Contract to kill: GNAS mutation., PMID:40050874
Pathogenic germline variants in Chinese pancreatic adenocarcinoma patients., PMID:40044664
Discovery of mutations predictive of survival benefit from immunotherapy in first-line NSCLC: A retrospective machine learning study of IMpower150 liquid biopsy data., PMID:40043417
Insights Gained From an Ultrarare Case of Progressive Osseous Heteroplasia With Severe Complications., PMID:40026961
Impact of genetic mutations on prognosis and chemotherapy efficacy in advanced appendiceal carcinoma: insights from the nationwide Japanese comprehensive genomic profiling test database., PMID:40019690
[Mutation Detection of Plasma Circulating Tumor DNA Associated with Multiple Myeloma]., PMID:40017198
Pancreatic Mixed Acinar-neuroendocrine Carcinoma in a Patient With a Germline PTEN Variant: A Case Report and Genomic Literature Review., PMID:40010976
Tumour-wide RNA splicing aberrations generate actionable public neoantigens., PMID:39972144
A biallelically active embryonic enhancer dictates GNAS imprinting through allele-specific conformations., PMID:39910084
Pseudohypoparathyroidism Type 1b with Digital Clubbing., PMID:39894498
Targeted gene sequencing and bioinformatics analysis of patients with gallbladder neuroendocrine carcinoma: A case report., PMID:39817132
TP53 Alterations Are an Independent Adverse Prognostic Indicator in Pseudomyxoma Peritonei of Appendiceal Origin Following Cytoreductive Surgery and Intraperitoneal Chemotherapy., PMID:39812318
Identification of Novel and Rare GNAS Mutations in Craniofacial Fibrous Dysplasia., PMID:39800353
Dynamic Changes in Circulating Tumor DNA During Immunotherapy for Head and Neck Cancer: SHIZUKU-HN Study., PMID:39796090
[Clinical and genetic characteristics analysis of two children with comorbidity of two rare genetic diseases]., PMID:39779334
[GNAS mutational analysis in differentiating fibrous dysplasia and liposclerosing myxofibrous tumor]., PMID:39762174
Combined Molecular Subclass and Immune Phenotype Correlate to Atezolizumab Plus Radiation Therapy Response in Invasive Bladder Cancer: BPT-ART Phase 2 Study., PMID:39755215
Comprehensive characterization of MCL-1 in patients with colorectal cancer: Expression, molecular profiles, and outcomes., PMID:39740007
Real-World Evidence of the Prevalence of Driver Mutations in Anorectal Melanoma., PMID:39739287
Heterodisomy in the GNAS locus is also a cause of pseudohypoparathyroidism type 1B (iPPSD3)., PMID:39736869
gnas Knockdown Induces Obesity and AHO Features in Early Zebrafish Larvae., PMID:39684386
Lung adenocarcinomas with mucinous histology: clinical, genomic, and immune microenvironment characterization and outcomes to immunotherapy-based treatments and KRASG12C inhibitors., PMID:39637943
[Application of 9-gene panel in assisting fine needle aspiration cytology to diagnose thyroid cancer]., PMID:39622737
Skipping of Exon 20 in EP300: A Novel Variant Linked to Rubinstein-Taybi Syndrome With Atypical and Severe Clinical Manifestations., PMID:39603792
Next-generation sequencing improves diagnostic accuracy of imaging and carcinoembryonic antigen alone for pancreatic cystic neoplasms., PMID:39567272
Recurrent small variants in NESP55/NESPAS associated with broad GNAS methylation defects and pseudohypoparathyroidism type 1B., PMID:39541438
Early-Life Stress Influences the Transcriptional Activation of Alpha-2A Adrenergic Receptor and Associated Protein Kinase A Signaling Molecules in the Frontal Cortex of Rats., PMID:39532806
Genotype-Phenotype Correlation of GNAS Gene: Review and Disease Management of a Hotspot Mutation., PMID:39456695
For research use only. Not for human or drug use.
