Catalog No.
YHF53401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Cys205
Predicted molecular weight
24.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P62820
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ras-related protein Rab-1A, YPT1-related protein, RAB1A, RAB1
An RNAi screen of Rab GTPase genes in Caenorhabditis elegans reveals that morphogenesis has a higher demand than stem cell niche maintenance for rab-1 in the somatic cells of the reproductive system., PMID:40239019
Exploring Potential Drug Targets in Multiple Cardiovascular Diseases: A Study Based on Proteome-Wide Mendelian Randomization and Colocalization Analysis., PMID:40026415
Increased ocular plasma cells induce damaging α-synuclein+ microglia in autoimmune uveitis., PMID:40015479
Involvement of GTPases and vesicle adapter proteins in Heparan sulfate biosynthesis: role of Rab1A, Rab2A and GOLPH3., PMID:39804811
C118P Suppresses Gastric Cancer Growth via Promoting Autophagy-Lysosomal Degradation of RAB1A., PMID:39771598
TRAPPopathies: Severe Multisystem Disorders Caused by Variants in Genes of the Transport Protein Particle (TRAPP) Complexes., PMID:39769094
The potential role of vesicle transport-related small GTPases rabs in abiotic stress responses., PMID:39729968
Movement of the endoplasmic reticulum is driven by multiple classes of vesicles marked by Rab-GTPases., PMID:39630612
Rab1 and Syntaxin 17 regulate hematopoietic homeostasis through β-integrin trafficking in Drosophila., PMID:39542172
Increased Rab1a accelerates osteoarthritis by inhibiting autophagy via activation of the mTORC1-S6K pathway., PMID:39521431
Clathrin-associated carriers enable recycling through a kiss-and-run mechanism., PMID:39300312
Insect-transmitted plant virus balances its vertical transmission through regulating Rab1-mediated receptor localization., PMID:39093698
Comprehensive knockout analysis of the RAB family small GTPases reveals an overlapping role of RAB2 and RAB14 in autophagosome maturation., PMID:38953305
A dual role of ERGIC-localized Rabs in TMED10-mediated unconventional protein secretion., PMID:38926505
Rab1b facilitates lipid droplet growth by ER-to-lipid droplet targeting of DGAT2., PMID:38809969
Sericin promotes chondrogenic proliferation and differentiation via glycolysis and Smad2/3 TGF-β signaling inductions and alleviates inflammation in three-dimensional models., PMID:38773312
A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence., PMID:38559361
MicroR-380-3p Reduces Sepsis-Induced Acute Kidney Injury via Regulating RAB1P to Restrain NF-κB Pathway., PMID:38220171
Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis., PMID:38177680
SNX32 is a host restriction factor that degrades African swine fever virus CP204L via the RAB1B-dependent autophagy pathway., PMID:38169281
Systematic analysis of variants escaping nonsense-mediated decay uncovers candidate Mendelian diseases., PMID:38091987
Deubiquitinating enzyme PSMD7 promotes bladder cancer development: Involvement of RAB1A stabilization., PMID:38040402
Rab1A functioned as a binding protein involved in Macrobrachium rosenbergii Taihu virus infection., PMID:37992912
RAB1A haploinsufficiency phenocopies the 2p14-p15 microdeletion and is associated with impaired neuronal differentiation., PMID:37924809
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy., PMID:37885576
Grouper Rab1 inhibits nodovirus infection by affecting virus entry and host immune response., PMID:37839541
Proteome-Wide Mendelian Randomization Analysis Identified Potential Drug Targets for Atrial Fibrillation., PMID:37581400
LncRNA BANCR promotes oral squamous cell carcinoma progression via regulating Rab1A signaling., PMID:37433101
Rab1A-Mediated Exosomal Sorting of miR-200c Enhances Breast Cancer Lung Metastasis., PMID:37274058
Novel Drug Targets for Atrial Fibrillation Identified Through Mendelian Randomization Analysis of the Blood Proteome., PMID:37212950
CD83+ B cells alleviate uveitis through inhibiting DCs by sCD83., PMID:37137669
Prognosis value and positive association of Rab1A/IL4Rα aberrant expression in gastric cancer., PMID:37117331
Inhibition of Rab1B Impairs Trafficking and Maturation of SARS-CoV-2 Spike Protein., PMID:37112806
Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b., PMID:37076474
Circ_RBM23 knockdown suppresses chemoresistance, proliferation, migration and invasion of sorafenib-resistant HCC cells through miR-338-3p/RAB1B axis., PMID:37075641
Structural insights into assembly of TRAPPII and its activation of Rab11/Ypt32., PMID:37068358
ELMOD3-Rab1A-Flotillin2 cascade regulates lumen formation via vesicle trafficking in Ciona notochord., PMID:36918025
Dual function of Rab1A in secretion and autophagy: hypervariable domain dependence., PMID:36781179
LINC00173 facilitates tumor progression by stimulating RAB1B-mediated PA2G4 and SDF4 secretion in nasopharyngeal carcinoma., PMID:36606322
Subcellular Distribution of BALF2 and the Role of Rab1 in the Formation of Epstein-Barr Virus Cytoplasmic Assembly Compartment and Virion Release., PMID:36602343
SGOL2 promotes prostate cancer progression by inhibiting RAB1A ubiquitination., PMID:36566018
The TRAPP complexes: discriminating GTPases in context., PMID:36481981
The TRAPP complexes: oligomeric exchange factors that activate the small GTPases Rab1 and Rab11., PMID:36477798
The complex, dynamic SpliceOme of the small GTPase transcripts altered by technique, sex, genetics, tissue specificity, and RNA base editing., PMID:36467401
Autophagy induced by Rab1a-ULK1 interaction promotes porcine reproductive and respiratory syndrome virus replication., PMID:36306941
Circ_0026123 promotes cisplatin resistance and progression of ovarian cancer by upregulating RAB1A through sequestering miR-543., PMID:36255068
The role of the Siglec-G ITIM domain during bacterial infection., PMID:35809291
miR-1285 Restrains Gastric Cancer Cell Growth and Causes Apoptosis by Negatively Regulating RAB1A., PMID:35695612
Targeted disruption of Gdi2 causes early embryonic lethality., PMID:35689892
Amino acids control blood glucose levels through mTOR signaling., PMID:35623230
For research use only. Not for human or drug use.
