Catalog No.
YHF52701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Phe377
Predicted molecular weight
44.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P62736
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Alpha-actin-2, Actin, aortic smooth muscle, Cell growth-inhibiting gene 46 protein, ACTSA, ACTVS, ACTA2, αSMA, α-SMA, α SMA
Therapeutic potential of Cordyceps militaris cultivated with Ginkgo biloba seeds for alleviating western diet-induced type 2 diabetes and diabetic nephropathy., PMID:40510419
Myofibroblast-like Cells and Junctional Complex Development Play a Role in Mouse Pubic Symphysis Remodeling During Pregnancy and Postpartum., PMID:40508115
Transcription factor SP1 drives TGF-β1-induced transformation of human tenon's capsule fibroblasts by transcription activation-mediated SNAI2 upregulation., PMID:40504458
Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms., PMID:40498456
Exploring the Mechanism of Action of Berberine on Arrhythmia After Myocardial Infarction: A Network Pharmacology, Molecular Docking, and Cellular Experimental Study., PMID:40496730
Activation of the Wnt signaling pathway and its role in epithelial-mesenchymal transition and hepatic fibrosis in alveolar echinococcosis., PMID:40496021
Metabolic dysfunction-associated steatotic liver disease: A story of muscle and mass., PMID:40495947
Evaluation of a Kenaf Nanocrystalline Cellulose-based Hydrogel Containing Platelet Lysate for Full-thickness Wound Healing., PMID:40495600
Dietary procyanidin B1 attenuates fibrogenesis and inflammation in hepatic fibrosis: research on the possible health benefits of procyanidin B1., PMID:40493038
Ferulic Acid Inhibits Partial Epithelial-Mesenchymal Transition in Renal Tubular Epithelial Cells and Mitigates Renal Interstitial Fibrosis by Regulating the HIF-1α/Twist Signaling Pathway., PMID:40490914
Treatment Patterns and Disease Burden of Juvenile Myasthenia Gravis in the United States: A Cohort Study Using Health Care Claims Databases., PMID:40489715
Hepatic stellate cell inhibition by angiotensin II receptor blocker mitigates liver injury and fibrosis via NF-κB-galectin-3 suppression in a rat nonalcoholic steatohepatitis model., PMID:40488883
A Novel Nude Mice Model for Studying the Pathogenesis of Keloid., PMID:40488291
Shenfushu granules attenuate diabetic kidney disease by inhibiting PIK3R1/protein kinase B/heparanase-mediated endothelial-mesenchymal transition., PMID:40487608
Amygdalin Alleviates Airway Inflammation and Remodeling in Asthma Mice: Involvement of TGF-β1/Smads Signaling Pathway., PMID:40485525
CYT997 Induces Apoptosis in Hypertrophic Scar Fibroblasts and Inhibits Scar Formation., PMID:40484336
Caspase-8-driven NLRP3 inflammasome activation exacerbates bronchopulmonary dysplasia by increasing the apoptosis and pyroptosis crosstalk of alveolar epithelial cells., PMID:40483833
S100a8 inhibitor Paquinimod attenuates coal dust-induced pulmonary fibrosis via blocking neutrophils-S100a8-Tlr4-macrophages signaling axis., PMID:40482449
Circular RNA hsa_circ_0008433 drives vascular smooth muscle cell modulation in intracranial aneurysm pathogenesis., PMID:40474527
Phospholipase A2 group IIA activates Indoleamine 2,3-dioxygenase 1 to drive the progression of pulmonary fibrosis., PMID:40473047
Reconstructed Human Skin Models to Study Superficial and Deep Skin Wound Healing In Vitro., PMID:40470675
The updated evidence of pirfenidone treated silicosis based on network pharmacology, molecular docking and experimental validation., PMID:40470053
[Mechanistic study on low expression of Ace2 gene activated senescence-related signals and promoted the progression of silicotic fibrosis in mice]., PMID:40468507
Innovative Approaches to NAFLD: Exploring the Role of Nicotinamide in Multicellular Microtissue Models of Liver Fibrosis., PMID:40464191
[Mechanism of vanillic acid against cardiac fibrosis induced by isoproterenol in mice based on Drp1/HK1/NLRP3 and mitochondrial apoptosis signaling pathways]., PMID:40461229
[Fucoidan sulfate regulates Hmox1-mediated ferroptosis to ameliorate myocardial injury in diabetic cardiomyopathy]., PMID:40461202
High Expression of CIP2A Can Promote the Proliferation, Migration, and Epithelial-Mesenchymal Transition of Diffuse Large B-Cell Lymphoma Cells., PMID:40459191
Amphiphilic Copolymers and Their Role in the Study of Membrane Proteins., PMID:40459069
Nanoscale therapeutics for erectile dysfunction: a meta-analysis of stem cell-derived extracellular vesicles as natural nanoparticles in diabetic rat models., PMID:40457489
Characteristics of 18F-FAPI-04 PET/CT in patients with peritoneal metastasis and to predict treatment efficacy, a head-to-head comparison with 18F-FDG PET/CT., PMID:40457405
Hepatic ferroptosis induced by Clonorchis sinensis exacerbates liver fibrosis., PMID:40455823
Therapeutic Effects and Molecular Mechanisms of KD025 in Intraocular Pressure Regulation., PMID:40452331
Comparison between endovascular and surgical treatment of acute arterial occlusive mesenteric ischemia., PMID:40452055
Inhibiting effect of LIPUS on epithelial-mesenchymal transition in lens epithelial cells., PMID:40449868
Combination of encorafenib and binimetinib followed by ipilimumab and nivolumab versus ipilimumab and nivolumab in patients with advanced melanoma with BRAFV600E or BRAFV600K mutations (EBIN): an international, open-label, randomised, controlled, phase 2 study., PMID:40449497
USP24 upregulation stabilizes PKA-Cα to promote lipogenesis, inflammation, and fibrosis during MASH progression., PMID:40448065
A critical role for IL-21/IL-21 receptor signaling in isoproterenol-induced cardiac remodeling., PMID:40447719
Allicin induced AMPK signaling attenuated Smad3 pathway mediated lung fibrosis., PMID:40447631
Xanthosomes loaded with recombinant TMEM219 for targeting IGFBP-3: A novel approach for targeted drug delivery to ameliorate liver fibrosis., PMID:40447257
Nonylphenol exposure induces myocardial fibrosis via the RhoA/ROCK1/MLC-signaling pathway., PMID:40446736
TFE3-rearranged PEComa-like neoplasm of the kidney with carcinoma-like morphology and rapid progression: a case report., PMID:40442772
Uncovering the molecular mechanisms of tonifying kidney and activating blood Decoction against myocardial fibrosis using network Pharmacology and experimental validation., PMID:40442166
Innovative unsaturated polyurethane for cardiac regeneration: Enhancing cytocompatibility and gene expression through gelatin modification., PMID:40441578
Recombinant human fibronectin segment (rhFN1024) hydrogel carried hPDLSCs to repair diabetic trauma by activated NF-κB signaling pathway., PMID:40438201
MAP2K2 Knockdown Suppresses Phenotypic Transformation of Vascular Smooth Muscle Cells in Aortic Dissection by Inactivating the JAK/STAT Signaling Pathway., PMID:40437968
Finerenone alleviates the high glucose-induced fibrosis in HK-2 cells by inhibiting EMT via the TGF-β1/Smads signaling., PMID:40436765
Macrophages-derived exosomal non-coding RNA circ_0055194 regulating miR-665/YAP1/Twist axis is involved in pulmonary fibrosis induced by Nd2O3., PMID:40436094
Mechanosensitive Piezo1 channel is highly expressed in the age-induced fibrotic uterus., PMID:40434609
Renal tubular epithelial cell related partial epithelial-mesenchymal transition in AAⅠ induced renal fibrosis via Wnt7b/β-catenin signaling., PMID:40432885
Spinach Extract Reduces Kidney Damage in Diabetic Rats by Impairing the AGEs/RAGE Axis., PMID:40429870