Catalog No.
EHF46101
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Met119
Predicted molecular weight
14.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61769
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Beta-2-microglobulin, B2M
Indoxyl sulfate as a potential tubular function marker across kidney disease models., PMID:40499558
Evaluating Serum Beta-2-Microglobulin Levels for Uremic Pericarditis Risk in End-Stage Renal Disease Patients., PMID:40497610
Increased serum soluble interleukin-2 receptor concentrations are linked to high-sensitivity troponin T and disease progression in systemic sclerosis., PMID:40492443
Mutations outside the MR1 antigen binding groove differentially inhibit presentation of exogenous antigens., PMID:40475583
Characterization of cytokine treatment on human pancreatic islets by top-down proteomics., PMID:40463221
Identification of multiomics and immune infiltration-associated biomarkers for early gastric cancer: a machine learning-based diagnostic model development study., PMID:40450287
Selection and validation of reference genes for RT-qPCR normalization in dormant cancer cells., PMID:40450038
Iron metabolism disorder and artesunate inhibiting tumor growth by inducing ferroptosis in Lymphangioleiomyomatosis., PMID:40448080
Stromal Cell-Derived Factor-1, P-Selectin, and Advanced Oxidation Protein Products with Mitochondrial Dysfunction Concurrently Impact Cerebral Vessels in Patients with Normoalbuminuric Diabetic Kidney Disease and Type 2 Diabetes Mellitus., PMID:40429625
New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics., PMID:40421421
Urinary NGAL Outperforms 99mTc-MAG3 Renography in Predicting DCD Kidney Graft Function., PMID:40421388
Prognostic impact of biomarkers in PMBCL: rationale for early integration of immune checkpoint inhibitors., PMID:40416849
An Efficient Luminol-H2O2 Electrochemiluminescence System with Porous Bimetallic Organic Gels as Signal Booster and Elaborate Heterosequence Aptamer as Recognition Component for Ultrasensitive Biosensing., PMID:40373155
Quantitative Proteome Analysis of Plasma Extracellular Vesicles Identifies Three Proteins with Potential Diagnostic Value for Mycobacterium bovis Infection in Cows., PMID:40372928
In-silico discovery of type-2 diabetes-causing host key genes that are associated with the complexity of monkeypox and repurposing common drugs., PMID:40370100
Serum β2-microglobulin level is associated with the survival of HIV-associated diffuse large B-cell lymphoma: a retrospective study from China., PMID:40335742
Quadruple adenine base-edited allogeneic CAR T cells outperform CRISPR/Cas9 nuclease-engineered T cells., PMID:40324075
Somatic mutations in HLA class genes and antigen presenting molecules in malignant glioma., PMID:40323360
Optimization of hypo-alloimmunogenic multispecific CAR-T and SARS-CoV-2-specific T cells for off-the-shelf adoptive cell therapy., PMID:40321414
Establishment of fracture blister model and analysis of plasma protein markers in rats., PMID:40297588
Reversible downregulation of HLA class I in adenoid cystic carcinoma., PMID:40254393
High Tumor Mutation Burden (TMB) and a Novel Somatic Mutation in the TREX1 Gene in a Patient with Aggressive and Refractory High-Grade B-Cell Lymphoma: A Case Report., PMID:40243506
A patient with RFX5 variant causing an expression defect in both HLA ABC and HLA DR., PMID:40240550
Transcriptomic sequencing of multiple salivary glands combined with bioinformatics analysis reveals key genes in primary Sjögren's syndrome., PMID:40227387
The role of B2M in cancer immunotherapy resistance: function, resistance mechanism, and reversal strategies., PMID:40191187
Development and validation of optimized lentivirus-like particles for gene editing tool delivery with Gag-Only strategy., PMID:40186294
Combined CLEC2d Expression and CD58 Loss Mitigate Rejection of Allogeneic T Cells., PMID:40171839
Translation of bi-directional transcripts enhances MHC-I peptide diversity., PMID:40165968
Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk., PMID:40135224
Deleterious KOs in the HLA Class I Antigen Processing and Presentation Machinery Induce Distinct Changes in the Immunopeptidome., PMID:40113210
Peptidomic profiling of mesenchymal stem cell-derived extracellular vesicles and anti-inflammatory activity of degraded peptides., PMID:40096816
Efficacy Evaluation of "Enhanced" Natural Killers with CISH and B2M Knockouts on Viability and Metabolic Status of 3D Glioblastoma Spheroid Cells in Patients., PMID:40071076
Prognostic Value of Serum β2-Microglobulin in Predicting Survival of Patients with Diffuse Large B-Cell Lymphoma., PMID:40066559
Increased risk of proximal tubular dysfunction due to occupational cadmium exposure: a survival analysis study., PMID:40042158
Exploration of the Prognostic Markers of Multiple Myeloma Based on Cuproptosis-Related Genes., PMID:40042106
Interim PET after 4 cycles predicts outcome in histomolecularly confirmed primary mediastinal B-cell lymphoma., PMID:40030008
Detrimental Effects of β2-Microglobulin on Muscle Metabolism: Evidence From In Vitro, Animal and Human Research., PMID:40026116
Identification of Causal Plasma Proteins in Hepatocellular Carcinoma via Two-Sample Mendelian Randomization and Integrative Transcriptomic‒Proteomic Analysis., PMID:39991825
Beta-2-microglobulin positive tumor cells and CD8 positive lymphocytes are associated with outcome in post-neoadjuvant colorectal cancer resections., PMID:39988058
The independent and interactive effects of heavy metal pollution and vitamin D deficiency on early kidney injury indicators: analysis of the National Health and Nutrition Examination Survey 2001-2004., PMID:39984925
Evaluation of suitable reference genes for gene expression studies in the developing mouse cortex using RT-qPCR., PMID:39966711
Dasatinib-resistant universal CAR-T cells proliferate in the presence of host immune cells and exhibit antitumor activity., PMID:39935177
Genomic mediators of acquired resistance to immunotherapy in metastatic melanoma., PMID:39933900
VSIG4+ tumor-associated macrophages mediate neutrophil infiltration and impair antigen-specific immunity in aggressive cancers through epigenetic regulation of SPP1., PMID:39920772
A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells., PMID:39906740
LLT1 overexpression renders allogeneic-NK resistance and facilitates the generation of enhanced universal CAR-T cells., PMID:39856752
Genetic determinants of COVID-19 severity and mortality: ACE1 Alu 287 bp polymorphism and ACE1, ACE2, TMPRSS2 expression in hospitalized patients., PMID:39850833
Identification of potential targets regulating neutrophil extracellular traps in acute rejection of kidney transplantation based on transcriptomics and animal experiments., PMID:39756163
Novel Inherited N-terminus TAP1 Variants and Severe Clinical Manifestations- Are Genotype-Phenotype Correlations Emerging?, PMID:39751995
Peroxiredoxin 6 maintains mitochondrial homeostasis and promotes tumor progression through ROS/JNK/p38 MAPK signaling pathway in multiple myeloma., PMID:39747460