Catalog No.
YHF42901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala349
Predicted molecular weight
41.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61371
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Insulin gene enhancer protein ISL-1, ISL1, Islet-1
Single-cell epigenomic and transcriptomic analysis unveils the pivotal role of GATA5/ISL1+ fibroblasts in cardiac repair post-myocardial infarction., PMID:40460294
Neuroimaging and immunofluorescence of the Pseudopus apodus brain: unraveling its structural complexity., PMID:40434439
The emergence of human primordial germ cell-like cells in stem cell-derived gastruloids., PMID:40138398
Cysteine-rich intestinal protein family: structural overview, functional diversity, and roles in human disease., PMID:40118853
Derivation of functional neurons from induced pluripotent stem cells using a simple neuromesodermal progenitor generation and rapid spinal cord neuron differentiation process., PMID:40080267
Force-activated zyxin assemblies coordinate actin nucleation and crosslinking to orchestrate stress fiber repair., PMID:39952249
Exploring Origin-Dependent Susceptibility of Smooth Muscle Cells to Aortic Diseases Through Intersectional Genetics., PMID:39925267
Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition., PMID:39874182
Foxm1 promotes differentiation of neural progenitors in the zebrafish inner ear., PMID:39761737
The role of sonic hedgehog signaling in the oropharyngeal epithelium during jaw development., PMID:39727066
Enhancing cardiac regeneration: direct reprogramming of fibroblasts into myocardial-like cells using extracellular vesicles secreted by cardiomyocytes., PMID:39718680
Runx3, Brn3a and Isl1 interplay orchestrates the transcriptional program in the early stages of proprioceptive neuron development., PMID:39715266
Transcriptional factor ISL1 regulates palate development by tuning the SHH cascade., PMID:39704783
Regulation of neuronal fate specification and connectivity of the thalamic reticular nucleus by the Ascl1-Isl1 transcriptional cascade., PMID:39625482
EphrinB2-mediated CDK5/ISL1 pathway enhances cardiac lymphangiogenesis and alleviates ischemic injury by resolving post-MI inflammation., PMID:39557830
ISL1 and AQP5 complement each other to enhance gastric cancer cell stemness by regulating CD44 expression., PMID:39525012
Arabidopsis Actin-Binding Protein WLIM2A Links PAMP-Triggered Immunity and Cytoskeleton Organization., PMID:39519192
MiRNA29a-3p negatively regulates ISL1-Integrin β1 axis to suppress gastric cancer progression., PMID:39490753
Subtyping of pancreatic neuroendocrine tumors by transcription factors, hormones, histology, and patient outcome., PMID:39377913
EZH2 specifically regulates ISL1 during embryonic urinary tract formation., PMID:39358471
DVL/GSK3/ISL1 pathway signaling: unraveling the mechanism of SIRT3 in neurogenesis and AD therapy., PMID:39267160
Deficient GATA6-CXCR7 signaling leads to bicuspid aortic valve., PMID:39253784
CREB activates the MafA promoter through proximal E-boxes and a CCAAT motif in pancreatic β-cells., PMID:39189982
ARX, PDX1, ISL1, and CDX2 Expression Distinguishes 5 Subgroups of Pancreatic Neuroendocrine Tumors With Correlations to Histology, Hormone Expression, and Outcome., PMID:39147030
Global identification of LIM genes in response to different heat stress regimes in Lactuca sativa., PMID:39103763
ISL1-overexpressing BMSCs attenuate renal ischemia-reperfusion injury by suppressing apoptosis and oxidative stress through the paracrine action., PMID:39066917
PCSK2 can be Useful in a Panel Approach to Distinguish Foregut and Midgut Neuroendocrine Tumors., PMID:39034588
ISLET-1 expression in soft tissue neoplasms reveals high sensitivity but moderate specificity for desmoplastic small round cell tumors and potential utility as a diagnostic biomarker., PMID:39018925
Tandem LIM domain-containing proteins, LIMK1 and LMO1, directly bind to force-bearing keratin intermediate filaments., PMID:39003737
Lhx4 surpasses its paralog Lhx3 in promoting the differentiation of spinal V2a interneurons., PMID:38970652
Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors and is Required for Placenta Morphogenesis and Vasculature Formation., PMID:38923264
Human Genetics of Ventricular Septal Defect., PMID:38884729
Cardiac Transcription Factors and Regulatory Networks., PMID:38884718
A new Prdm1-Cre line is suitable for studying the second heart field development., PMID:38880275
Missense mutation of ISL1 (E283D) is associated with the development of type 2 diabetes., PMID:38819467
miR-652-3p Suppressed the Protective Effects of Isoflurane Against Myocardial Injury in Hypoxia/Reoxygenation by Targeting ISL1., PMID:38801481
A global gene regulatory program and its region-specific regulator partition neurons into commissural and ipsilateral projection types., PMID:38781326
A mammalian tripartite enhancer cluster controls hypothalamic Pomc expression, food intake, and body weight., PMID:38652744
Revolutionizing pediatric neuroblastoma treatment: unraveling new molecular targets for precision interventions., PMID:38601081
Exosomes derived from induced cardiopulmonary progenitor cells alleviate acute lung injury in mice., PMID:38589686
Unraveling the significance of PPP1R1A gene in pancreatic β-cell function: A study in INS-1 cells and human pancreatic islets., PMID:38574885
Single-Cell Transcriptome Analysis of Small Cell Neuroendocrine Carcinoma of the Endometrium Reveals ISL1 as a Potential Biomarker for Diagnosis and Treatment., PMID:38538277
Investigating LIM (Lin-11, Isl-1, and Mec-3) Kinases and Their Correlation with Pathological Events and Microtubule Dynamics in an Experimental Model of Spinal Cord Injury in Rats., PMID:38481685
Generation of a ISL1 homozygous knockout stem cell line (WAe009-A-1G) by episomal vector-based CRISPR/Cas9 system., PMID:38452706
HRAS-Mutant Cardiomyocyte Model of Multifocal Atrial Tachycardia., PMID:38415356
A novel gain-of-function STAT3 variant in infantile-onset diabetes associated with multiorgan autoimmunity., PMID:38404237
Sall genes regulate hindlimb initiation in mouse embryos., PMID:38386912
ISL1 and POU4F1 Directly Interact to Regulate the Differentiation and Survival of Inner Ear Sensory Neurons., PMID:38267260
The trxG protein ULT1 regulates Arabidopsis organ size by interacting with TCP14/15 to antagonize the LIM peptidase DA1 for H3K4me3 on target genes., PMID:38217289
Taurine promotes insulin synthesis by enhancing Isl-1 expression through miR-7a/RAF1/ERK1/2 pathway., PMID:38117455
For research use only. Not for human or drug use.
