Catalog No.
YHF40601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro6-Lys254
Predicted molecular weight
30.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61158
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Actin-like protein 3, Actin-related protein 3, ACTR3, ARP3
Dendrobium huoshanense polysaccharide inhibits NSCLC proliferation and immune evasion via FXR1-IL-35 axis signaling pathway., PMID:40259042
Molecular mechanism of Arp2/3 complex activation by nucleation-promoting factors and an actin monomer., PMID:40048273
Should it stay or should it go: gap junction protein GJA1/Cx43 conveys damaged lysosomes to the cell periphery to potentiate exocytosis., PMID:39394955
Impact of NSD1 Alternative Transcripts in Actin Filament Formation and Cellular Division Pathways in Fibroblasts., PMID:39336709
LINC01133 promotes pancreatic ductal adenocarcinoma epithelial-mesenchymal transition mediated by SPP1 through binding to Arp3., PMID:38987572
Minimal Change Disease: Pathogenetic Insights from Glomerular Proteomics., PMID:38891801
BAG3 regulates cilia homeostasis of glioblastoma via its WW domain., PMID:38655699
PLD1 promotes spindle assembly and migration through regulating autophagy in mouse oocyte meiosis., PMID:38513669
Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament., PMID:38267598
Modified Danzhi Xiaoyao Powder (MDXP) improves the corneal damage in dry eye disease (DED) mice through phagocytosis., PMID:38070838
Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins., PMID:37898612
Transition State of Arp2/3 Complex Activation by Actin-Bound Dimeric Nucleation-Promoting Factor., PMID:37549294
Methylation Levels in the Promoter Region of FHIT and PIAS1 Genes Associated with Mastitis Resistance in Xinjiang Brown Cattle., PMID:37372369
mTORC1/rpS6 and mTORC2/PKC regulate spermatogenesis through Arp3-mediated actin microfilament organization in Eriocheir sinensis., PMID:37328709
ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells., PMID:37162507
Role and mechanism of actin-related protein 2/3 complex signaling in cancer invasion and metastasis: A review., PMID:37026902
Branching out in different directions: Emerging cellular functions for the Arp2/3 complex and WASP-family actin nucleation factors., PMID:36907023
Extracellular vesicles from human Fallopian tubal fluid benefit embryo development in vitro., PMID:36895886
es-Arp3 and es-Eps8 regulate spermatogenesis via microfilaments in the seminiferous tubule of Eriocheir sinensis., PMID:36709695
Is Your Kid Actin Out? A Series of Six Patients With Inherited Actin-Related Protein 2/3 Complex Subunit 1B Deficiency and Review of the Literature., PMID:36708766
Actin related protein 2/3 complex subunit 1 up-regulation in the hypothalamus prevents high-fat diet induced obesity., PMID:36382618
CRISPR-Cas9 Arabidopsis mutants of genes for ARPC1 and ARPC3 subunits of ARP2/3 complex reveal differential roles of complex subunits., PMID:36307477
Vasoactive intestinal peptide-VIPR2 signaling regulates tumor cell migration., PMID:36237322
A condensate dynamic instability orchestrates actomyosin cortex activation., PMID:35978196
Nuclear interaction of Arp2/3 complex and BRAFV600E promotes aggressive behavior and vemurafenib resistance of thyroid cancer., PMID:35968344
Dietary Inclusion of Dried Chicory Root Affects Cecal Mucosa Proteome of Nursery Pigs., PMID:35804609
Arp2/3 complex activity is necessary for mouse ESC differentiation, times formative pluripotency, and enables lineage specification., PMID:35658973
Genome-wide DNA methylation profiles of autism spectrum disorder., PMID:35353793
Battle of the bulge: the ARP2/3 complex form(in)s an actin phalanx to thwart fungal infection., PMID:35233629
WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues., PMID:34919802
Weighted Gene Co-Expression Network Analysis and Treatment Strategies of Tumor Recurrence-Associated Hub Genes in Lung Adenocarcinoma., PMID:34868230
ACTR3 promotes cell migration and invasion by inducing epithelial mesenchymal transition in pancreatic ductal adenocarcinoma., PMID:34790395
Decreased exosome-delivered miR-486-5p is responsible for the peritoneal metastasis of gastric cancer cells by promoting EMT progress., PMID:34686196
Identification of Arp2/3 Complex Subunits as Prognostic Biomarkers for Hepatocellular Carcinoma., PMID:34307456
Actin-related protein 2/3 complex plays a critical role in the aquaporin-2 exocytotic pathway., PMID:34180716
MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes., PMID:34106209
Rac1/Wave2/Arp3 Pathway Mediates Rat Blood-Brain Barrier Dysfunction under Simulated Microgravity Based on Proteomics Strategy., PMID:34068233
The actin nucleation factors JMY and WHAMM enable a rapid Arp2/3 complex-mediated intrinsic pathway of apoptosis., PMID:33872315
LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton., PMID:33869174
E-selectin negatively regulates polymorphonuclear neutrophil transmigration through altered endothelial junction integrity., PMID:33811691
Chlamydia trachomatis TmeA Directly Activates N-WASP To Promote Actin Polymerization and Functions Synergistically with TarP during Invasion., PMID:33468693
Identification of the Biomarkers and Pathological Process of Heterotopic Ossification: Weighted Gene Co-Expression Network Analysis., PMID:33391181
Integrated Bioinformatics Analysis of mRNAs and miRNAs Identified Potential Biomarkers of Oral Squamous Cell Carcinoma., PMID:32597160
HBV DNA integrates into upregulated ZBTB20 in patients with hepatocellular carcinoma., PMID:32319639
Proline-rich 11 (PRR11) drives F-actin assembly by recruiting the actin-related protein 2/3 complex in human non-small cell lung carcinoma., PMID:32169900
Identification of hub genes and pathways in cholangiocarcinoma by coexpression analysis., PMID:32116234
Testin regulates the blood-testis barrier via disturbing occludin/ZO-1 association and actin organization., PMID:31975378
Discovering novel lung cancer associated antigens and the utilization of their autoantibodies in detection of lung cancer., PMID:31839396
Partial loss of actin nucleator actin-related protein 2/3 activity triggers blebbing in primary T lymphocytes., PMID:31698518
LncRNA AC009022.1 enhances colorectal cancer cells proliferation, migration, and invasion by promoting ACTR3B expression via suppressing miR-497-5p., PMID:31637768
For research use only. Not for human or drug use.
