Catalog No.
YHF38701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Cys188
Predicted molecular weight
23.24 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P60953
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CDC42, G25K GTP-binding protein, Cell division control protein 42 homolog
Reelin-LRP8 signaling mediates brain dissemination of breast cancer cells via abluminal migration., PMID:40506610
ARP2/3 regulates cell surface dynamics of CeTOCA-1 in C. elegans zygotes., PMID:40501091
Myotonic dystrophy-related CDC42-binding kinase alpha (MRCKα) mediates methionine- and leucine-stimulated β-casein synthesis in bovine mammary epithelial cells via targeting mTOR., PMID:40487111
Negative feedback equalizes polarity sites in a multi-budding yeast., PMID:40482649
Dynamic relocation of PKA regulatory subunits during sperm capacitation: Linking PKA to the CatSper signaling complex., PMID:40478882
Physics of notochord tube expansion in ascidians., PMID:40472029
Targeting of CIP4-Calcineurin Signalosomes Improves Cardiac Structure and Function After Myocardial Infarction., PMID:40462891
Cdc42 Activation in Anti-nephrin Antibody-Induced Nephropathy., PMID:40459930
Biological characteristics of spontaneous ovarian cancer in Microtusfortis., PMID:40457786
Myeloid PGGT1B Deficiency Promotes Psoriasiform Dermatitis by Promoting the Secretion of Inflammatory Factors., PMID:40430037
Simulated Microgravity-Induced Alterations in PDAC Cells: A Potential Role for Trichostatin A in Restoring Cellular Phenotype., PMID:40429900
Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion., PMID:40421714
[RGL1 overexpression promotes metastasis of colorectal cancer by upregulating motile focal adhesion assembly via activating the CDC42/RAC1 complex]., PMID:40415435
RHOA-associated disorder can be non-mosaic., PMID:40414526
PPI network identifies interacting pathogenic signaling pathways in Candida albicans., PMID:40391893
Roles played by IL-8 in altering dynamics of trabecular meshwork cells after human cytomegalovirus infection., PMID:40353220
Berberine promotes apoptosis and inhibits the migration of oral squamous carcinoma cells through inhibition of the RAGE/PI3K/AKT/mTOR pathway., PMID:40339228
The Role of the p21-Activated Kinase Family in Tumor Immunity., PMID:40332759
PCP protein Prickle 1 regulates Sertoli cell and testis function via cytoskeletal organization through the recruitment of multiple regulatory proteins., PMID:40327382
Small GTPase Rac promotes hyphal formation and microconidiogenesis in Trichophyton rubrum., PMID:40320710
Cryptosporidium modifies intestinal microvilli through an exported virulence factor., PMID:40300595
Disrupting Cdc42 activation-driven filopodia formation with low-intensity ultrasound and microbubbles: A novel strategy to block ovarian cancer metastasis., PMID:40300280
Loss of Nup160 dysregulates Cdc42 in the podocytes of podocyte-specific Nup160 knockout mice., PMID:40298220
Clathrin-Independent Carriers/Glycosylphosphatidylinositol-Anchored-Protein-Enriched Endosomal Compartment Endocytic Pathway Is Critical for Enterovirus A71 Entry Into Human Oral Epidermoid Carcinoma KB Cells., PMID:40298088
Development of Acquired Resistance in Alpelisib-treated Gastric Cancer Cells With PIK3CA Mutations and Overcoming Strategies., PMID:40295072
Fluorometholone inhibits corneal epithelial proliferation, migration via targeting Rho GTPases: RhoA, Rac1, and Cdc42., PMID:40268157
A novel finding relates to the involvement of ATF3/DOCK8 in Alzheimer's disease pathogenesis., PMID:40267290
EGF-Induced Macropinocytosis Promotes NAV1-Dependent Internalization of Occludin in Keratinocytes., PMID:40266031
IQGAP3 deficiency leads to non-syndromic hearing loss via inhibition of CDC42 enzyme activity., PMID:40239295
Chlamydia trachomatis TmeA promotes pedestal-like structure formation through N-WASP and TOCA-1 interactions., PMID:40231845
Pathogenesis of Focal Segmental Glomerulosclerosis Caused by a Leu754Val Mutation in ARHGAP32., PMID:40231370
Aripiprazole alleviates the high prolactin levels induced by amisulpride via distinct molecular mechanisms: a network pharmacology and molecular docking study., PMID:40229786
Molecular basis identification and hypnotic drug interactions for cognitive impairment related to sleep deprivation., PMID:40229714
Mechanistic Study of Chaga Medicinal Mushroom Inonotus obliquus (Agaricomycetes) Phenolic Compounds in the Treatment of Liver Cancer: A Database and Simulation Approach., PMID:40228216
NUCKS1 exacerbates hepatocellular carcinoma cell proliferation and metastasis via the upregulation of Cdc42., PMID:40226459
Alcaligenes faecalis induces intestinal T helper-17 cells by enhancing Rorc transcription through E3 ligase Trim21-mediated Fbxw7 degradation., PMID:40215968
Serum interleukin-18 levels are specifically elevated in auto-inflammatory diseases involving the pyrin inflammasome: A study on 516 patients., PMID:40204564
Integrated multi-omics identify key signalling pathways for notochord lumenogenesis in ascidian Ciona savignyi., PMID:40199341
ARHGAP12 suppresses F-actin assembly to control epithelial tight junction mechanics and paracellular leak pathway permeability., PMID:40198220
Quantitative Proteomic Analysis Indicates That Pggt1b Deficiency Promotes Cytokine Secretion in Resiquimod-Stimulated Bone Marrow-Derived Macrophages via the NF-κB Pathway., PMID:40192076
Where to grow and where to go., PMID:40187481
Cell deformations generated by stochastic actomyosin waves drive in vivo random-walk swimming migration., PMID:40183280
CDC42 Regulatory Patterns Related To Inflammatory Bowel Disease and Hyperglycemia., PMID:40183002
Secreted exosomes induce filopodia formation., PMID:40161676
Glomerular mesangial cells derived complement factor H regulates complement activation, influences cell proliferation, and maintains actin cytoskeleton., PMID:40157080
DNA methylation memory of pancreatic acinar-ductal metaplasia transition state altering Kras-downstream PI3K and Rho GTPase signaling in the absence of Kras mutation., PMID:40156071
Gastrodin Mitigates Ketamine-Induced Inhibition of F-Actin Remodeling and Cell Migration by Regulating the Rho Signaling Pathway., PMID:40149625
Activity-dependent regulation of Cdc42 by Ephexin5 drives synapse growth and stabilization., PMID:40138406
PI(3,4,5)P3-mediated Cdc42 activation regulates macrophage podosome assembly., PMID:40126693
The experimental study of the effect of fluid shear force on the migration rate of human umbilical vein endothelial cells., PMID:40117976
For research use only. Not for human or drug use.
