Catalog No.
YHF36201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met35-Val403
Predicted molecular weight
45.43 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P60484
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mutated in multiple advanced cancers 1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MMAC1, PTEN, TEP1, Phosphatase and tensin homolog
Early growth response 1 as a key regulator of PD-L1 expression and immune evasion in extranodal NK/T-cell lymphoma., PMID:40514360
EZH2 inhibition and 5-azacytidine enhance antitumor immunity in PTEN-deficient glioblastoma by activation viral mimicry response., PMID:40514071
Integrating Aggressive-Variant Prostate Cancer-Associated Tumor Suppressor Gene Status with Clinical Variables to Refine Prognosis and Predict Androgen Receptor Pathway Inhibitor Response in Metastatic Hormone-Sensitive Setting., PMID:40508118
SLIT/ROBO Pathway and Prostate Cancer: Gene and Protein Expression and Their Prognostic Values., PMID:40508075
Generation and characterization of a mouse model of conditional Chd4 knockout in the endometrial epithelium., PMID:40501592
Engineered EVs-Mediated miR-222 Targeting PTEN/FN1 Axis Reverses Anthracycline Resistance in HER2-Negative Breast Cancer., PMID:40501184
Metabolite Analog-Induced Proteome Changes., PMID:40498186
Long non-coding RNA GAS5 promotes neuronal apoptosis in spinal cord injury via the miR-21/PTEN axis., PMID:40496261
Dose-dependent immunotoxic mechanisms of celastrol via modulation of the PI3K-Akt signaling pathway., PMID:40495892
Anti-Cancer Role of Ellagic Acid by Modulating the Altered PI3K/PTEN/Akt Pathway in Bladder Cancer., PMID:40493901
The T follicular helper/T follicular helper regulatory pathway in FVIII immune responses in mice., PMID:40493881
PINK1 suppresses malignant phenotypes in esophageal squamous cell carcinoma., PMID:40490793
Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway., PMID:40487763
Dexmedetomidine improves septic acute kidney injury by inhibiting inflammation and oxidative stress through the activation of the Pink1/Park2 autophagy pathway., PMID:40485166
LDHA-Mediated H3K18 Lactylation Promotes the Glycolysis in Non-Small Cell Lung Cancer Through Targeting PTEN., PMID:40481934
Altered Expression of MeCP2 and PTEN Genes in the Molecular Basis of Specific Learning Disorder., PMID:40478485
Integrative in silico analysis of per- and polyfluorinated alkyl substances (PFAS)-associated molecular alterations in human cancers: a multi-cancer framework for predicting toxicogenomic disruption., PMID:40474796
The Developing Retina Undergoes Mitochondrial Remodeling via PINK1/PRKN-dependent Mitophagy., PMID:40472989
Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer., PMID:40472846
MicroRNA-100-5p Exacerbates Myocardial Ischemia-Reperfusion Injury Through Downregulation of PRMT5., PMID:40471103
SFXN1 promotes bladder cancer metastasis by restraining PINK1-dependent mitophagy., PMID:40468051
MBD2 promotes B cell differentiation and BCR signaling in systemic lupus erythematosus by regulating the LEF-1-PTEN-PI3K axis., PMID:40467564
Inhibition of NR2F2 restores hormone therapy response to endocrine refractory breast cancers., PMID:40465692
Distribution and potential involvement of PTEN in the innate immune response during viral infections in Cherry Valley ducks., PMID:40463389
[Molecular mechanism of Siwu Decoction in treating premature ovarian insufficiency based on mitophagy pathway modulated and mediated by estrogen receptor subtype]., PMID:40461227
The role of long non-coding ribonucleic acid HOXA11-AS in endometriosis therapy., PMID:40457415
A comprehensive, multi-center, immunogenomic analysis of melanoma brain metastases., PMID:40457397
Anti-cancer properties of chitosan /Lactobacillus acidophilus secretome nanoparticle on signaling pathways of colorectal cancer in colon adenocarcinoma (Caco-2) cell line., PMID:40457310
Cisplatin palbociclib combination differentially modulates PTEN AKT signaling via Hsp90 in hepatocellular carcinoma cells., PMID:40456804
Proteomics based discovery of Salvia miltiorrhiza Bunge treating Parkinson's disease through the PINK1/Parkin pathway., PMID:40456474
PINK1/Parkin-based live-cell quantitative FRET imaging for mitophagy drug screening., PMID:40451779
Whey protein hydrolysate alleviated acetaminophen-induced hepatocyte pyroptosis by activating mitophagy., PMID:40451585
Involvement of the PINK1/Parkin signaling pathway in 4-vinylcyclohexene diepoxide-induced ovary toxicity in rats., PMID:40451534
Deciphering the role of Hashimoto's Thyroiditis-related key genes in thyroid cancer via detailed in silico analysis followed by the experimental validation., PMID:40450370
hpCasMINI: An engineered hypercompact CRISPR-Cas12f system with boosted gene editing activity., PMID:40442121
Vitexin alleviates cerebral ischemia/reperfusion injury by regulating mitophagy via the SIRT1/PINK1/Parkin pathway., PMID:40441663
Hyperbaric oxygen therapy attenuates carbon monoxide-induced lung injury by restoring mitochondrial dynamics and suppressing Pink1/Parkin-mediated mitophagy., PMID:40441279
Mutational analysis and protein expression of PI3K/AKT pathway in four mucinous cystadenocarcinoma of the breast., PMID:40437613
Impaired Mitophagy Contributes to Pyroptosis in Sarcopenic Obesity Zebrafish Skeletal Muscle., PMID:40431451
2-Amino-3-Chlorobenzoic Acid from Streptomyces coelicolor: A Cancer Antagonist Targeting PI3K/AKT Markers via miRNA Modulation., PMID:40430441
Molecular Interplay Between PTEN, ARID1A, PD-L1, and MMR in Asian Ovarian Clear Cell Carcinoma: Implications for Immunotherapy Response and Patient Stratification., PMID:40430056
Low Fluoride Regulates Macrophage Polarization Through Mitochondrial Autophagy Mediated by PINK1/Parkin Axis., PMID:40427540
mTOR pathway diseases: challenges and opportunities from bench to bedside and the mTOR node., PMID:40426219
Ketogenic diet attenuates microglia-mediated neuroinflammation by inhibiting NLRP3 inflammasome activation via HDAC3 inhibition to activate mitophagy in experimental autoimmune encephalomyelitis., PMID:40421817
miR-29a-3p compositely regulates the COL6A6/PTEN-PI3K/Akt/CUX1 feedback loop to participate in the proliferation and invasion of pituitary adenomas., PMID:40419838
Human endogenous retrovirus W family envelope protein (ERVWE1) regulates macroautophagy activation and micromitophagy inhibition via NOXA1 in schizophrenia., PMID:40419114
A heterozygous variation of PINK1 is potentially associated with essential tremor in a Chinese family., PMID:40418408
Genomics-led approach to drug testing in models of undifferentiated pleomorphic sarcoma., PMID:40415599
An orally-administered nanotherapeutics with gold nanospheres supplying for rheumatoid arthritis therapy by re-shaping gut microbial tryptophan metabolism., PMID:40414887
Androgen receptor plays critical role in regulating cervical cancer cell migration., PMID:40409531
For research use only. Not for human or drug use.
