Catalog No.
YHF33901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly22-Lys68
Predicted molecular weight
31.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P60022
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BD1, BD-1, Defensin, beta 1, hBD-1, Beta-defensin 1, HBD1, DEFB1
Multi-omics analyses, cell experiments, and network pharmacology tools identified key proteins and candidate drugs for alopecia areata treatment., PMID:40442619
Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems., PMID:40395933
Integrative genomic pan-cancer analysis reveals the prognostic significance of DEFB1 in tumors., PMID:40244529
Edaravone alleviates Pseudomonas aeruginosa associated-acute lung injury by inhibiting inflammation and promoting anti-microbial peptide production., PMID:40158431
Beta-defensin 1 knockdown ameliorates the characteristics of intervertebral disc degeneration by altering nucleus pulposus and annulus fibrosus cell phenotypes via suppression of the extracellular signal-regulated kinase signaling pathway., PMID:40057017
HAS-CIRCpedia-5280 sponges miR-4712-5p inhibited colon cancer autophagyinduced by human beta-defensin-1., PMID:40050987
Distinct anti-microbial peptides expression patterns and microbiome profiles in skin of Tunisian endemic Pemphigus foliaceus patients., PMID:40009223
Aged garlic extract enhances the production of β‑defensin 4 via activation of the Wnt/β‑catenin pathway in mouse gingiva., PMID:39781190
Gene expression responses of CF airway epithelial cells exposed to elexacaftor/tezacaftor/ivacaftor suggest benefits beyond improved CFTR channel function., PMID:39437760
Intestinal microbiome dysbiosis increases Mycobacteria pulmonary colonization in mice by regulating the Nos2-associated pathways., PMID:39412514
Polymorphic variation of the DEFB1 gene might contribute to the development of ankylosing spondylitis: a preliminary study., PMID:39395079
Association between DEFB1 rs11362 and Caries Susceptibility in Permanent Dentition: A Cross Sectional Study., PMID:39327247
Tumor-derived DEFB1 induces immune tolerance by inhibiting maturation of dendritic cell and impairing CD8+ T cell function in esophageal squamous cell carcinoma., PMID:39246704
The Effect of Seminal Plasma on the Equine Endometrial Transcriptome., PMID:39246124
Restoration of the Lost Human Beta Defensin-1 Protein in Cancer as a Strategy to Improve the Efficacy of Chemotherapy., PMID:39137365
The DEFB1 gene rs11362 A/G genetic variant is associated with risk of developing CAD: a case-control study., PMID:38973431
Possible Impact of Human β-defensin 1 on sperm motility in infertile men with abnormal sperm parameters., PMID:38688100
Curcumin effects on age-related changes in oral immunity: an in vivo study., PMID:38634264
Drug repositioning for immunotherapy in breast cancer using single-cell analysis., PMID:38589404
Innate Immunity Activation in Newly Diagnosed Ileocolonic Crohn's Disease: A Cohort Study., PMID:38319717
Relationship between biofilm-forming microorganisms (BFM: Staphylococcus aureus and Pseudomonas aeruginosa) and DEFB1 gene variants on β-defensin levels in periprosthetic joint infection (PJI)., PMID:38285273
Identify gestational diabetes mellitus by deep learning model from cell-free DNA at the early gestation stage., PMID:38168840
Shen Qi Wan ameliorates nephritis in chronic kidney disease via AQP1 and DEFB1 regulation., PMID:38113630
Identification and validation of novel prognostic signatures based on m5C methylation patterns and tumor EMT profiles in head and neck squamous cell carcinoma., PMID:37907576
Effect of Supplementation with Curcuma longa and Rosmarinus officinalis Extract Mixture on Acute Phase Protein, Cathelicidin, Defensin and Cytolytic Protein Gene Expression in the Livers of Young Castrated Polish White Improved Bucks., PMID:37895281
Effects of Schumann resonance on the proliferation and migration of normal human epidermal keratinocytes and the expression of DEFB1 and SIRT1., PMID:37697693
Extract of Sophorae flavescentis radix-Cnidii fructus couplet medicines treats vulvovaginal candidiasis by affecting the vaginal mucosal barrier., PMID:37668465
[Polymorphisms associated with dental caries in pediatric populations: a systematic review]., PMID:37540722
Toll-like Receptors and Cytokine Modulation by Goat Milk Extracellular Vesicles in a Model of Intestinal Inflammation., PMID:37446274
Identifying biomarkers associated with the diagnosis of ulcerative colitis via bioinformatics and machine learning., PMID:37322958
A new prognostic model for RHOV, ABCC2, and CYP4B1 to predict the prognosis and association with immune infiltration of lung adenocarcinoma., PMID:37197482
Identification of four novel loci associated with psychotropic drug-induced weight gain in a Swiss psychiatric longitudinal study: A GWAS analysis., PMID:37173452
DNA Methylation of Window of Implantation Genes in Cervical Secretions Predicts Ongoing Pregnancy in Infertility Treatment., PMID:36982674
Evaluation of Beta-Defensin 1 and Mannose-Binding Lectin 2 Polymorphisms in Children with Dental Caries Compared to Caries-Free Controls: A Systematic Review and Meta-Analysis., PMID:36832361
High-Throughput Screening for Epigenetic Compounds That Induce Human β-Defensin 1 Synthesis., PMID:36830097
Innate immune response of human periodontal ligament fibroblasts via the Dectin-1/Syk pathway., PMID:36748551
β-Defensin-1 Regulates Influenza Virus Infection in Human Bronchial Epithelial Cells through the STAT3 Signaling Pathway., PMID:36678471
Associations of PART1 and DEFB1 polymorphisms with Dental Caries in twelve-year-old children in Southern China: a cross-sectional study., PMID:36597064
Human beta-defensin 1 circulating level and gene polymorphism in non-segmental vitiligo Egyptian patients., PMID:36535830
Identification of putative orthologs of clinically relevant antimicrobial peptides in the equine ocular surface and amniotic membrane., PMID:36478371
Antimicrobial peptides β-defensin family: Expression and regulation in the endometrium during the estrous cycle and pregnancy in pigs., PMID:36442607
TRAF3IP2-IL-17 Axis Strengthens the Gingival Defense against Pathogens., PMID:36281065
Molecular cloning, expression analysis of interleukin 17D (cysteine knot cytokine) from Amphiprion clarkii and their functional characterization and NFκB pathway activation using FHM cells., PMID:35636699
An Immune-Related Gene Signature for Predicting Neoadjuvant Chemoradiotherapy Efficacy in Rectal Carcinoma., PMID:35603163
Beneficial Effect of Kidney Bean Resistant Starch on Hyperlipidemia-Induced Acute Pancreatitis and Related Intestinal Barrier Damage in Rats., PMID:35566136
Non-invasive transcriptomic analysis using mRNAs in skin surface lipids obtained from children with mild-to-moderate atopic dermatitis., PMID:35462437
In-silico analysis of non-synonymous single nucleotide polymorphisms in human β-defensin type 1 gene reveals their impact on protein-ligand binding sites., PMID:35452998
Implications of Human Antimicrobial Peptide Defensin Beta-1 in Clinical Oral Squamous Cell Carcinoma Patients via an Integrated Bioinformatics Approach., PMID:35222682
Urine proteomics as a non-invasive approach to monitor exertional rhabdomyolysis during military training., PMID:35134564
Prostaglandin-endoperoxide synthase (PTGS2) and Defensin beta 1 (DEFB1) gene polymorphisms are not associated with periodontitis in Malays., PMID:34958064
For research use only. Not for human or drug use.
