Catalog No.
YHF31701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro21-Cys94
Predicted molecular weight
34.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P59666
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HP3, Neutrophil defensin 3, HNP-3, HNP-2, DEF3, HP-3, Defensin, alpha 3, DEFA3, HP-2, HP2
Robust Serum Proteomic Signatures of APOE2., PMID:40501769
GLIO-Select: Machine Learning-Based Feature Selection and Weighting of Tissue and Serum Proteomic and Metabolomic Data Uncovers Sex Differences in Glioblastoma., PMID:40362575
Proteomic Profiling of Tears in Blau Syndrome Patients in Identification of Potential Disease Biomarkers., PMID:39125957
Progression from healthy periodontium to gingivitis and periodontitis: Insights from bioinformatics-driven proteomics - A systematic review with meta-analysis., PMID:38873831
Identify gestational diabetes mellitus by deep learning model from cell-free DNA at the early gestation stage., PMID:38168840
Characterization of virus-mediated autoimmunity and the consequences for pathological process in patients with systemic lupus erythematosus., PMID:37369873
Differential Gene Expression Among Patients With Heart Failure Experiencing Pain., PMID:36920122
Relaxin-2 plasma levels in atrial fibrillation are linked to inflammation and oxidative stress markers., PMID:36566255
Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement activation., PMID:36348270
Single-cell RNA sequencing analysis dissected the osteo-immunology microenvironment and revealed key regulators in osteoporosis., PMID:36257255
Age-restricted functional and developmental differences of neonatal platelets., PMID:35962592
Human Neutrophil Defensins Disrupt Liver Interendothelial Junctions and Aggravate Sepsis., PMID:35935811
PPBP gene as a biomarker for coronary heart disease risk in postmenopausal Thai women., PMID:35734636
Interleukin-6 absence triggers intestinal microbiota dysbiosis and mucosal immunity in mice., PMID:35276634
Commonly expressed key transcriptomic profiles of sepsis in the human circulation and brain via integrated analysis., PMID:35032827
Resveratrol Improves Growth Performance, Intestinal Morphology, and Microbiota Composition and Metabolism in Mice., PMID:34539617
High Migration and Invasion Ability of PGCCs and Their Daughter Cells Associated With the Nuclear Localization of S100A10 Modified by SUMOylation., PMID:34336846
Whole blood RNA sequencing reveals a differential transcriptomic profile associated with cervical insufficiency: a pilot study., PMID:33627129
Identification of Significant Genes in HIV/TB via Bioinformatics Analysis., PMID:33067206
Differentiating Total- or Partial-Body Irradiation in Baboons Using mRNA Expression Patterns: A Proof of Concept., PMID:32991726
Discovery of Selenocysteine as a Potential Nanomedicine Promotes Cartilage Regeneration With Enhanced Immune Response by Text Mining and Biomedical Databases., PMID:32792959
Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations., PMID:32499510
Non-invasive prenatal testing reveals copy number variations related to pregnancy complications., PMID:31485271
Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis., PMID:30718392
Low-Copy Number Polymorphism in DEFA1/DEFA3 Is Associated with Susceptibility to Hospital-Acquired Infections in Critically Ill Patients., PMID:29950924
Decellularized colorectal cancer matrix as bioactive microenvironment for in vitro 3D cancer research., PMID:29244195
PPBP and DEFA1/DEFA3 genes in hyperlipidaemia as feasible synergistic inflammatory biomarkers for coronary heart disease., PMID:28420383
Low α-defensin gene copy number increases the risk for IgA nephropathy and renal dysfunction., PMID:27358498
Oncogenic relevant defensins: expression pattern and proliferation characteristics of human tumor cell lines., PMID:26711780
Differential Gene Expression Profiling of Orbital Adipose Tissue in Thyroid Orbitopathy., PMID:26444724
The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML., PMID:26029847
Decreased Expression of Innate Immunity-Related Genes in Peripheral Blood Mononuclear Cells from Patients with IgG4-Related Disease., PMID:25973893
Quantitative Proteomic Analysis of Peripheral Blood Mononuclear Cells in Ankylosing Spondylitis by iTRAQ., PMID:25788137
Stable phenotype of B-cell subsets following cryopreservation and thawing of normal human lymphocytes stored in a tissue biobank., PMID:25327569
IL-18 cytokine levels modulate innate immune responses and cryptosporidiosis in mice., PMID:25155632
Relevance of α-defensins (HNP1-3) and defensin β-1 in diabetes., PMID:25083086
Evolution of primate α and θ defensins revealed by analysis of genomes., PMID:24557891
Homeostatic tissue responses in skin biopsies from NOMID patients with constitutive overproduction of IL-1β., PMID:23226210
Critical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes., PMID:22852767
Alpha-defensin DEFA1A3 gene copy number elevation in Danish Crohn's disease patients., PMID:21701837
Increased genomic copy number of DEFA1/DEFA3 is associated with susceptibility to severe sepsis in Chinese Han population., PMID:20502117
High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes., PMID:18470942
MRPS18CP2 alleles and DEFA3 absence as putative chromosome 8p23.1 modifiers of hearing loss due to mtDNA mutation A1555G in the 12S rRNA gene., PMID:18154640
The role of human innate immune factors in nasal colonization by Staphylococcus aureus., PMID:17913546
Inter-population variability of DEFA3 gene absence: correlation with haplotype structure and population variability., PMID:17214878
Isolation and expression profiling of genes upregulated in the peripheral blood cells of systemic lupus erythematosus patients., PMID:16769699
Copy number polymorphisms are not a common feature of innate immune genes., PMID:16617005
Human defensin gene copy number polymorphisms: comprehensive analysis of independent variation in alpha- and beta-defensin regions at 8p22-p23., PMID:16039093
Copy number polymorphism and expression level variation of the human alpha-defensin genes DEFA1 and DEFA3., PMID:15944200
Interferon and granulopoiesis signatures in systemic lupus erythematosus blood., PMID:12642603
For research use only. Not for human or drug use.
