Catalog No.
YHF31601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu20-Cys94
Predicted molecular weight
10.55 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P59665
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neutrophil defensin 1, DEFA1, HP1, DEF1, DEFA2, HNP-2, MRS, HNP-1, HP-1, Defensin, alpha 1, HP-2, HP2
Identification of Cardiometabolic Protein Biomarkers for Acute Myocardial Infarction Using Olink Proteomics., PMID:40013238
DEFA1, Primarily Expressed at the Invasive Tumor Front, Promotes OSCC Cell Invasion and Tumor Growth., PMID:39993801
Identification, Clinical Values, and Prospective Pathway Signaling of Lipid Metabolism Genes in Epilepsy and AED Treatment., PMID:39812994
Untargeted blood serum proteomics identifies novel proteins related to neurological recovery after human spinal cord injury., PMID:39020346
Bioinformation Analysis of Differential Expression Proteins in Different Processes of COVID-19., PMID:38717820
Identify gestational diabetes mellitus by deep learning model from cell-free DNA at the early gestation stage., PMID:38168840
Evaluation of cerebrospinal fluid levels for ALOX5, S100B, DEFA1, and GFAP in infectious meningitis., PMID:38115295
Identification of key genes and regulatory mechanisms in adult degenerative scoliosis., PMID:38103507
Integration of Metabolomics and Transcriptomics Reveals Major Metabolic Pathways and Potential Biomarkers Involved in Pulmonary Tuberculosis and Pulmonary Tuberculosis-Complicated Diabetes., PMID:37522815
Alpha-Defensin 1: An Emerging Periodontitis Biomarker., PMID:37443537
Multi-omic and comparative analyses revealed monocyte-derived alpha-defensin-1 correlated with COVID-19 severity and inhibited SARS-CoV-2 infection., PMID:37254949
Synovial Fluid Proteomics From Serial Aspirations of ACL-Injured Knees Identifies Candidate Biomarkers., PMID:37191559
Local Immune Biomarker Expression Depending on the Uterine Microbiota in Patients with Idiopathic Infertility., PMID:37108732
Quantitative tissue proteome profile reveals neutrophil degranulation and remodeling of extracellular matrix proteins in early stage gallbladder cancer., PMID:36686780
Identification of perturbed pathways rendering susceptibility to tuberculosis in type 2 diabetes mellitus patients using BioNSi simulation of integrated networks of implicated human genes., PMID:36476775
Comparative transcriptome analysis in the caput segment of yak and cattleyak epididymis., PMID:36368116
Association between Immunologic Markers and Cirrhosis in Individuals from a Prospective Chronic Hepatitis C Cohort., PMID:36358697
Human Neutrophil Defensins Disrupt Liver Interendothelial Junctions and Aggravate Sepsis., PMID:35935811
PPBP gene as a biomarker for coronary heart disease risk in postmenopausal Thai women., PMID:35734636
Plasma Proteomic Analysis Identified Proteins Associated with Faulty Neutrophils Functionality in Decompensated Cirrhosis Patients with Sepsis., PMID:35681439
Expression of anti-fungal peptide, β-defensin 118 in oral fibroblasts induced by C. albicans β-glucan-containing particles., PMID:35507985
Spatial Metabolomics Identifies Distinct Tumor-Specific Subtypes in Gastric Cancer Patients., PMID:35395077
RNA Sequencing in COVID-19 patients identifies neutrophil activation biomarkers as a promising diagnostic platform for infections., PMID:35081105
Elevated Levels of Neutrophil Activated Proteins, Alpha-Defensins (DEFA1), Calprotectin (S100A8/A9) and Myeloperoxidase (MPO) Are Associated With Disease Severity in COVID-19 Patients., PMID:34746027
CEACAM5 overexpression is a reliable characteristic of CD133-positive colorectal cancer stem cells., PMID:34092615
Arsenic exposure in drinking water reduces Lgr5 and secretory cell marker gene expression in mouse intestines., PMID:33957193
Identification of Significant Genes in HIV/TB via Bioinformatics Analysis., PMID:33067206
Serum proteins may facilitate the identification of Kawasaki disease and promote in vitro neutrophil infiltration., PMID:32973234
Circulating mRNA and microRNA profiling analysis in patients with ischemic stroke., PMID:32626985
Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations., PMID:32499510
In Vitro Salivary Protein Adsorption Profile on Titanium and Ceramic Surfaces and the Corresponding Putative Immunological Implications., PMID:32349305
PR3 levels are impaired in plasma and PBMCs from Arabs with cardiovascular diseases., PMID:31935243
Identification of differentially expressed proteins associated with recurrence in ovarian endometriotic cysts., PMID:31714804
Polymorphisms in the P2X7 receptor, and differential expression of Toll-like receptor-mediated cytokines and defensins, in a Canadian Indigenous group., PMID:31578370
Non-invasive prenatal testing reveals copy number variations related to pregnancy complications., PMID:31485271
Impact of Maternal Malnutrition on Gut Barrier Defense: Implications for Pregnancy Health and Fetal Development., PMID:31248104
Human platelets and megakaryocytes express defensin alpha 1., PMID:31116063
Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis., PMID:30718392
ATF4 Deficiency Promotes Intestinal Inflammation in Mice by Reducing Uptake of Glutamine and Expression of Antimicrobial Peptides., PMID:30452920
Interaction between mesenchymal stromal cell-derived extracellular vesicles and immune cells by distinct protein content., PMID:30378105
Low-Copy Number Polymorphism in DEFA1/DEFA3 Is Associated with Susceptibility to Hospital-Acquired Infections in Critically Ill Patients., PMID:29950924
A fusion protein composed of the DSL domain of Dll1 and RGD motif protects cryptic stem cells in irradiation injury., PMID:29444821
Excellent Diagnostic Characteristics for Ultrafast Gene Profiling of DEFA1-IL1B-LTF in Detection of Prosthetic Joint Infections., PMID:28637910
PPBP and DEFA1/DEFA3 genes in hyperlipidaemia as feasible synergistic inflammatory biomarkers for coronary heart disease., PMID:28420383
Requirement of Gαq/Gα11 Signaling in the Preservation of Mouse Intestinal Epithelial Homeostasis., PMID:28174748
Oncogenic relevant defensins: expression pattern and proliferation characteristics of human tumor cell lines., PMID:26711780
Differential Gene Expression Profiling of Orbital Adipose Tissue in Thyroid Orbitopathy., PMID:26444724
Quantitative proteomic analysis of paired colorectal cancer and non-tumorigenic tissues reveals signature proteins and perturbed pathways involved in CRC progression and metastasis., PMID:26054784
The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML., PMID:26029847
Identification of differentially expressed genes associated with prognosis of B acute lymphoblastic leukemia., PMID:25802479
For research use only. Not for human or drug use.
