Catalog No.
YHF26901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu30-Ser187
Predicted molecular weight
19.67 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P58499
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C21orf11, Pancreatic-derived factor, FAM3B, Protein FAM3B, Cytokine-like protein 2-21, C21orf76, PANDER
Potential drug targets for Neuromyelitis optica spectrum disorders (NMOSD): A Mendelian randomization analysis., PMID:40294019
Identification of druggable targets in acute kidney injury by proteome- and transcriptome-wide Mendelian randomization and bioinformatics analysis., PMID:40148878
Mendelian randomization analysis of plasma proteins reveals potential novel tumor markers for gastric cancer., PMID:39875498
Antiapoptotic and Prometastatic Roles of Cytokine FAM3B in Triple-Negative Breast Cancer., PMID:38997857
Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression., PMID:37847647
Colostrum Features of Active and Recovered COVID-19 Patients Revealed Using Next-Generation Proteomics Technique, SWATH-MS., PMID:37628421
Identification of the immune-related biomarkers in Behcet's disease by plasma proteomic analysis., PMID:37264476
Identification of Potential Indicators for Survival in Patients with Thyroid Cancer Based on Expression of FAM3 Members., PMID:37183945
Identification of rare loss-of-function variants in FAM3B associated with non-syndromic orofacial clefts., PMID:37105387
Cardioprotective factors against myocardial infarction selected in vivo from an AAV secretome library., PMID:36044596
FAM3 Family as Prognostic Factors for Head and Neck Squamous Cell Carcinoma., PMID:35538834
Construction of miRNA-mRNA-TF Regulatory Network for Diagnosis of Gastric Cancer., PMID:34840985
Identifying potential therapeutic targets of Tang-Yi-Ping for the treatment of impaired glucose tolerance: a tandem mass tag-labeled quantitative proteomic analysis., PMID:34790738
The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus., PMID:33975953
In silico screening using bulk and single-cell RNA-seq data identifies RIMS2 as a prognostic marker in basal-like breast cancer: A retrospective study., PMID:33879671
Identification and validation of an immune-related gene-based prognostic index for bladder cancer., PMID:33042413
Upregulation of FAM3B Promotes Cisplatin Resistance in Gastric Cancer by Inducing Epithelial-Mesenchymal Transition., PMID:32442162
FAM3B/PANDER-Like Carbohydrate-Binding Domain in a Glycosyltransferase, POMGNT1., PMID:32306360
Gene Variants That Affect Levels of Circulating Tumor Markers Increase Identification of Patients With Pancreatic Cancer., PMID:31676359
Structure-based identification of potential novel inhibitors targeting FAM3B (PANDER) causing type 2 diabetes mellitus through virtual screening., PMID:31517548
Increased pancreatic-derived factor (PANDER) levels in gestational diabetes mellitus., PMID:30982368
MiR-15b and miR-322 inhibit SETD3 expression to repress muscle cell differentiation., PMID:30796205
FAM3B promotes progression of oesophageal carcinoma via regulating the AKT-MDM2-p53 signalling axis and the epithelial-mesenchymal transition., PMID:30565387
FAM3B (PANDER) functions as a co-activator of FOXO1 to promote gluconeogenesis in hepatocytes., PMID:30488666
FAM3B/PANDER inhibits cell death and increases prostate tumor growth by modulating the expression of Bcl-2 and Bcl-XL cell survival genes., PMID:29357840
FAM3 gene family: A promising therapeutical target for NAFLD and type 2 diabetes., PMID:29221790
Effects of circulating member B of the family with sequence similarity 3 on the risk of developing metabolic syndrome and its components: A 5-year prospective study., PMID:29178453
FAM3B mediates high glucose-induced vascular smooth muscle cell proliferation and migration via inhibition of miR-322-5p., PMID:28536423
Polymorphism of receptor-type tyrosine-protein phosphatase delta gene in the development of non-alcoholic fatty liver disease., PMID:28497593
Association of serum pancreatic derived factor (PANDER) with beta-cell dysfunction in type 2 diabetes mellitus., PMID:28161382
Hepatic SILAC proteomic data from PANDER transgenic model., PMID:27642623
Quantitative proteomic profiling reveals hepatic lipogenesis and liver X receptor activation in the PANDER transgenic model., PMID:27394190
Elevated circulating level of a cytokine, pancreatic-derived factor, is associated with metabolic syndrome components in a Chinese population., PMID:27181109
Identification of FAM3D as a new endogenous chemotaxis agonist for the formyl peptide receptors., PMID:26966188
Hepatic nutrient and hormonal regulation of the PANcreatic-DERived factor (PANDER) promoter., PMID:26123584
F3MB(PANDER) decreases mice hepatic triglyceride and is associated with decreased DGAT1 expression., PMID:25679806
Enhanced glucose tolerance in pancreatic-derived factor (PANDER) knockout C57BL/6 mice., PMID:25217499
Integrative identification of Epstein-Barr virus-associated mutations and epigenetic alterations in gastric cancer., PMID:25173755
[PANDER in regulation of glucose and lipid metabolism]., PMID:24665741
PANDER transgenic mice display fasting hyperglycemia and hepatic insulin resistance., PMID:24468680
Whole genome expression profiling and screening for differentially expressed cytokine genes in human bone marrow endothelial cells treated with humoral inhibitors in liver cirrhosis., PMID:24043211
Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficits., PMID:24041763
Family with sequence similarity 3 gene family and nonalcoholic fatty liver disease., PMID:23855304
[The latest research progress on FAM3 gene family]., PMID:23671995
FAM3B PANDER and FAM3C ILEI represent a distinct class of signaling molecules with a non-cytokine-like fold., PMID:23333428
A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk., PMID:23300138
Knockdown of FAM3B triggers cell apoptosis through p53-dependent pathway., PMID:23246487
A non-secretory form of FAM3B promotes invasion and metastasis of human colon cancer cells by upregulating Slug expression., PMID:23059759
Inflammatory signals enhance piezo2-mediated mechanosensitive currents., PMID:22921401
Upregulation of pancreatic derived factor (FAM3B) expression in pancreatic β-cells by MCP-1 (CCL2)., PMID:21664946
For research use only. Not for human or drug use.
