Catalog No.
YHF26201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln34-Gly318
Predicted molecular weight
33.03 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P58335
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CMG-2, ANTXR2, Anthrax toxin receptor 2, Capillary morphogenesis gene 2 protein, CMG2
The interaction of HT-2 toxin and Akt1 on gene expression regulation in Kashin-Beck disease pathogenesis., PMID:40449756
Skeletal muscle biomarkers of amyotrophic lateral sclerosis: a large-scale, multi-cohort proteomic study., PMID:40313273
Genetic Insights Into Hyaline Fibromatosis Syndrome: A Case Report of an ANTXR2 Mutation Featuring a Rare Variant c.697+1G>A., PMID:40177156
Rare case of hyaline fibromatosis syndrome., PMID:39521447
Prognostic factors for wellbeing in patients with hyaline fibromatosis syndrome., PMID:39258861
Large scale serum proteomics identifies proteins associated with performance decline and clinical milestones in Duchenne muscular dystrophy., PMID:39148831
Potential mechanism of Luoshi Neiyi prescription in endometriosis based on serum pharmacochemistry and network pharmacology., PMID:39135784
Transmembrane protein TMEM230, regulator of metalloproteins and motor proteins in gliomas and gliosis., PMID:38960477
Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS., PMID:38951798
Hyaline fibromatosis syndrome: a rare, yet recognizable syndrome., PMID:38814306
Investigating the Influence of ANTXR2 Gene Mutations on Protective Antigen Binding for Heightened Anthrax Resistance., PMID:38674361
Discovery and validation of molecular patterns and immune characteristics in the peripheral blood of ischemic stroke patients., PMID:38650649
Hyaline Fibromatosis Syndrome Diagnosed by Whole Genome Sequencing., PMID:38385928
Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS., PMID:38196621
Hemokinin-1 induces transcriptomic alterations in pain-related signaling processes in rat primary sensory neurons independent of NK1 tachykinin receptor activation., PMID:37965042
Infantile Systemic Hyalinosis: A Case Report and Literature Review., PMID:37927741
Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS., PMID:37873269
Multisystemic Manifestations of Hyaline Fibromatosis Syndrome: Implications for Diagnosis and Management., PMID:37859675
Identification and verification of genes associated with hypoxia microenvironment in Alzheimer's disease., PMID:37759083
Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits., PMID:37747038
Genome-wide scan for runs of homozygosity in South American Camelids., PMID:37605116
Hypercalcemia as a rare presentation of hyaline fibromatosis syndrome from different Sudanese families: two case reports., PMID:37264371
PCGEM1 promotes cell proliferation and migration in endometriosis by targeting miR-124-3p-mediated ANTXR2 expression., PMID:36915057
Host Cell Transcriptional Tuning with CRISPR/dCas9 to Mitigate the Effects of Toxin Exposure., PMID:36318971
Sex Hormone-regulated CMG2 Is Involved in Breast and Prostate Cancer Progression., PMID:36316045
Mechanobiological responses of astrocytes in optic nerve head due to biaxial stretch., PMID:36114477
The Capillary Morphogenesis Gene 2 Triggers the Intracellular Hallmarks of Collagen VI-Related Muscular Dystrophy., PMID:35886995
Juvenile Hyaline Fibromatosis: Report of a Case with a Novel ANTXR2 Gene Mutation., PMID:35752930
Hyaline fibromatosis syndrome with a novel 4.41-kb deletion in ANTXR2 gene: A case report and literature review., PMID:35726349
[Hyaline juvenile fibromatosis: clinic, diagnostics, treatment]., PMID:35362706
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis., PMID:35212873
Anthrax toxin receptor 2 is a potential therapeutic target for non-small cell lung carcinoma with MET exon 14 skipping mutations., PMID:35189107
Harnessing bacterial toxins to treat pain., PMID:34931071
Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons., PMID:34931070
Multiple stages of evolutionary change in anthrax toxin receptor expression in humans., PMID:34782625
Hyaline fibromatosis syndrome: a case presenting with gingival enlargement as the only clinical manifestation and a report of two new mutations in the ANTXR2 gene., PMID:34627224
Juvenile hyaline fibromatosis: A clinicopathological study of five cases., PMID:34624626
A Severe Case of Infantile Systemic Hyalinosis in an Asian Child: A Product of Consanguinity., PMID:34414050
Nociceptive Sensory Neurons Mediate Inflammation Induced by Bacillus Anthracis Edema Toxin., PMID:34413846
Infantile systemic hyalinosis: Variable grades of severity., PMID:34341308
[Analysis of pathogenic variants in a Chinese pedigree affected with hyaline fibromatosis syndrome]., PMID:33751531
Genetic deletion of CMG2 exacerbates systemic-to-pulmonary shunt-induced pulmonary arterial hypertension., PMID:33749907
Novel variation in ANTXR2 gene causing hyaline fibromatosis syndrome: A report from India., PMID:33724566
Enhanced Collagen Deposition in the Duodenum of Patients with Hyaline Fibromatosis Syndrome and Protein Losing Enteropathy., PMID:33147779
High-Density Lipoprotein Carries Markers That Track With Recovery From Stroke., PMID:32844720
Reengineering anthrax toxin protective antigen for improved receptor-specific protein delivery., PMID:32792013
Hyaline fibromatosis syndrome: A case report., PMID:32771412
Anthrax Edema and Lethal Toxins Differentially Target Human Lung and Blood Phagocytes., PMID:32698436
Protective effect of anthrax toxin receptor 2 polymorphism rs4333130 against the risk of ankylosing spondylitis., PMID:32664053
For research use only. Not for human or drug use.
