Catalog No.
YHF25801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr519-Asn726
Predicted molecular weight
26.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P58215
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Lysyl oxidase homolog 3, LOXL3, LOXL, Lysyl oxidase-like protein 3
Loxl3 Affects Palatal Shelf Elevation by Regulating Cell Proliferation and Collagen Deposition., PMID:40429955
Machine learning-based in-silico analysis identifies signatures of lysyl oxidases for prognostic and therapeutic response prediction in cancer., PMID:40186284
Role of Lysyl Oxidase-Like Protein 3 in the Pathogenesis of Graves' Orbitopathy in Orbital Fibroblasts., PMID:39546293
Expression of LOXL3, NES, and SNAI1 in Melanoma Genesis and Progression., PMID:39273022
LOXL3 Silencing Hampers the Metastasis and Angiogenesis of Gastric Cancer Cells Dependent on Ferroptosis Activation., PMID:39192165
Novel LOXL3-associated stickler syndrome-like phenotype: a case report., PMID:38957076
Comprehensive Analysis of the Associations of LOXL1-4 with Prognosis and Immune Infiltration in Breast Cancer., PMID:38518152
CEBPA facilitates LOXL2 and LOXL3 transcription to promote BCL-2 stability and thus enhances the growth and metastasis of lung carcinoma cells in vitro., PMID:38242344
LOXL3 Inhibits Autophagy of Chondrocytes by Activating Rheb in Osteoarthritis., PMID:38153629
Pan-Cancer Analysis of the LOX Family Reveals that LOX Affects Tumor Prognosis by Affecting Immune Infiltration., PMID:38073445
Homozygous LOXL2 variant in individuals affected by non-syndromic occipital encephalocele., PMID:37345575
Lysyl oxidase-like 3 restrains mitochondrial ferroptosis to promote liver cancer chemoresistance by stabilizing dihydroorotate dehydrogenase., PMID:37253718
The Genetic Confirmation and Clinical Characterization of LOXL3-Associated MYP28: A Common Type of Recessive Extreme High Myopia., PMID:36917121
Identification of a copper metabolism-related gene signature for predicting prognosis and immune response in glioma., PMID:36856182
Progressive degeneration of the retina in Loxl3 mutant mouse model of Stickler syndrome., PMID:36610533
LncRNA CFAR promotes cardiac fibrosis via the miR-449a-5p/LOXL3/mTOR axis., PMID:36334219
N6-methyladenosine reader YTHDF3 regulates melanoma metastasis via its 'executor'LOXL3., PMID:36324258
Identification of copper metabolism and cuproptosis-related subtypes for predicting prognosis tumor microenvironment and drug candidates in hepatocellular carcinoma., PMID:36275743
Knock-Out of the Five Lysyl-Oxidase Family Genes Enables Identification of Lysyl-Oxidase Pro-Enzyme Regulated Genes., PMID:36232621
Identification and validation of roles of lysyl oxidases in the predictions of prognosis, chemotherapy and immunotherapy in glioma., PMID:36160460
Hearing Loss in Stickler Syndrome: An Update., PMID:36140739
Implications of lysyl oxidase-like protein 3 expression in the periodontium of diabetic rats., PMID:36134856
Correlation of Matrisome-Associatted Gene Expressions with LOX Family Members in Astrocytomas Stratified by IDH Mutation Status., PMID:36076905
LOXL3-promoted hepatocellular carcinoma progression via promotion of Snail1/USP4-mediated epithelial-mesenchymal transition., PMID:35841383
Differential roles for lysyl oxidase (like), family members in chronic obstructive pulmonary disease; from gene and protein expression to function., PMID:35670745
Loxl2 and Loxl3 Paralogues Play Redundant Roles during Mouse Development., PMID:35628534
Comprehensive Analysis on Prognosis and Immune Infiltration of Lysyl Oxidase Family Members in Pancreatic Adenocarcinoma With Experimental Verification., PMID:35433829
Diagnostic Value, Prognostic Value, and Immune Infiltration of LOX Family Members in Liver Cancer: Bioinformatic Analysis., PMID:35311155
Spatial collagen stiffening promotes collective breast cancer cell invasion by reinforcing extracellular matrix alignment., PMID:35292774
Apoptosis Activation and Autophagy Inhibition of Chondrocytes by Leptin by the Upregulation of LOXL3 in Osteoarthritis Pathogenesis., PMID:35035830
Next Generation Sequencing and Cytogenetic Based Evaluation of Indian Pierre Robin Sequence Families Reveals CNV Regions of Modest Effect and a Novel LOXL3 Mutation., PMID:34787502
Platelet-Released Growth Factors Induce Genes Involved in Extracellular Matrix Formation in Human Fibroblasts., PMID:34638874
Glycoprotein Pathways Altered in Frontotemporal Dementia With Autoimmune Disease., PMID:34539672
Identification of LOXL3-associating immune infiltration landscape and prognostic value in hepatocellular carcinoma., PMID:34448895
Polymorphisms in Lysyl Oxidase Family Genes Are Associated With Intracranial Aneurysm Susceptibility in a Chinese Population., PMID:34393991
LOXL3 Silencing Affected Cell Adhesion and Invasion in U87MG Glioma Cells., PMID:34360836
The Expression Patterns and Roles of Lysyl Oxidases in Aortic Dissection., PMID:34307505
Immunohistochemistry analysis reveals lysyl oxidase-like 3 as a novel prognostic marker for primary melanoma., PMID:33625099
The prognostic value of the lysyl oxidase family in ovarian cancer., PMID:33058284
Effect of mechanical injury and IL-1β on the expression of LOXs and MMP-1, 2, 3 in PCL fibroblasts after co-culture with synoviocytes., PMID:32971185
Evolving roles of lysyl oxidase family in tumorigenesis and cancer therapy., PMID:32693113
Exposure to desflurane anesthesia confers colorectal cancer cells metastatic capacity through deregulation of miR-34a/LOXL3., PMID:32658033
Lysyl Oxidase (LOX) Family Members: Rationale and Their Potential as Therapeutic Targets for Liver Fibrosis., PMID:32176358
Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3., PMID:31580073
LOXL3 Function Beyond Amino Oxidase and Role in Pathologies, Including Cancer., PMID:31340433
The analyses of SRCR genes based on protein-protein interaction network in esophageal squamous cell carcinoma., PMID:31217847
The plasma peptides of ovarian cancer., PMID:30598658
The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis., PMID:30536539
LOX/LOXL in pulmonary fibrosis: potential therapeutic targets., PMID:30457362
LOXL3 novel mutation causing a rare form of autosomal recessive Stickler syndrome., PMID:30362103
For research use only. Not for human or drug use.
