Catalog No.
YHF16401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp114
Predicted molecular weight
15.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P56279
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Oncogene TCL1, Oncogene TCL-1, Protein p14 TCL1, TCL1A, T-cell leukemia/lymphoma protein 1A, TCL1
Single-cell analysis reveals potential therapeutic markers of peripheral blood mononuclear cells from bladder cancer patients., PMID:40367012
Drug Repurposing to Inhibit Oncostatin M in Crohn's Disease., PMID:40363705
Cytoplasmic WEE1 Promotes Resistance to PD-1 Blockade Through Hyperactivation of the HSP90A/TCL1/AKT Signaling Axis in NANOGhigh Tumors., PMID:40067354
Single-cell transcriptomics reveals the immune mechanisms by which tonsillectomy improves clinical outcomes of recurrent Immuoglobulin A nephropathy after kidney transplant., PMID:39985963
TCL1A in naïve B cells as a therapeutic target for type 1 diabetes., PMID:39946833
B-cell intrinsic RANK signaling cooperates with TCL1 to induce lineage-dependent B-cell transformation., PMID:39198400
Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN)., PMID:39197587
Plasma proteometabolome in lung cancer: exploring biomarkers through bidirectional Mendelian randomization and colocalization analysis., PMID:39011643
[TCL1-family negative T-cell prolymphocytic leukemia with rapid progression of extranodal disease despite a normal white blood cell count]., PMID:38960645
Exosomal mRNA Cargo are biomarkers of tumor and immune cell populations in pediatric osteosarcoma., PMID:38852279
Zanubrutinib is effective in non-germinal-center B-cell-like diffuse large B-cell lymphoma with mutated CD79B, high TCL1A expression, or over- expressed MYC/BCL-2., PMID:38775302
TCL1A-expressing B cells are critical for tertiary lymphoid structure formation and the prognosis of oral squamous cell carcinoma., PMID:38764038
Determinants of mosaic chromosomal alteration fitness., PMID:38714703
A Cohort Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms: Results from ECOG-ACRIN E1Z11., PMID:38640040
[Durable remission of T-cell prolymphocytic leukemia with CLEC16A::IL2 after allogeneic hematopoietic stem cell transplantation]., PMID:38311387
CRISPR loss of function screening to identify genes involved in human primordial germ cell-like cell development., PMID:38091369
Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis., PMID:37932435
Exploration of Key Immune-Related Transcriptomes Associated with Doxorubicin-Induced Cardiotoxicity in Patients with Breast Cancer., PMID:37684436
T-Cell Prolymphocytic Leukemia: Diagnosis, Pathogenesis, and Treatment., PMID:37569479
A Multiplex Biomarker Assay Improves the Prediction of Survival in Epithelial Ovarian Cancer., PMID:37093685
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis., PMID:37046083
Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia., PMID:37023372
Subclinical rejection-free diagnostic after kidney transplantation using blood gene expression., PMID:36990211
TCL1A expression promotes aggressive biology in CLL., PMID:36951882
TCL1A acts as a tumour suppressor by modulating gastric cancer autophagy via miR-181a-5p-TCL1A-Akt/mTOR-c-MYC loop., PMID:36317339
The proto-oncogene TCL1A deregulates cell cycle and genomic stability in CLL., PMID:36179280
Computational gene expression analysis reveals distinct molecular subgroups of T-cell prolymphocytic leukemia., PMID:36129940
BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors., PMID:35767961
Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies., PMID:35704690
Noncanonical Function of AGO2 Augments T-cell Receptor Signaling in T-cell Prolymphocytic Leukemia., PMID:35259248
Integrated Bioinformatics and Validation Reveal Potential Biomarkers Associated With Progression of Primary Sjögren's Syndrome., PMID:34367157
[Analysis of the phenotypic heterogeneity of CD123-positive cells in Kikuchi-Fujimoto disease using a sequential immunoperoxidase labeling and erasing method]., PMID:34278759
TCL1A, B Cell Regulation and Tolerance in Renal Transplantation., PMID:34206047
Transcriptomic landscape of early age onset of colorectal cancer identifies novel genes and pathways in Indian CRC patients., PMID:34083590
Identification of a 5-Gene-Based Scoring System by WGCNA and LASSO to Predict Prognosis for Rectal Cancer Patients., PMID:33833937
Polymorphisms of T- cell leukemia 1A gene loci are not related to the development of adjuvant letrozole-induced adverse events in breast cancer., PMID:33760860
Protein dynamics analysis identifies candidate cancer driver genes and mutations in TCGA data., PMID:33550612
Noncanonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling., PMID:33301031
Exploiting B-cell Receptor Stereotypy to Design Tailored Immunotherapy in Chronic Lymphocytic Leukemia., PMID:33051305
Plasma Biomarkers of Reticular Pseudodrusen and the Risk of Progression to Advanced Age-Related Macular Degeneration., PMID:32974084
Microarray profile of B cells from Graves' disease patients reveals biomarkers of proliferation., PMID:32432440
Current understandings on T-cell prolymphocytic leukemia and its association with TCL1 proto-oncogene., PMID:32247279
HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors., PMID:31992715
TCL1 as a hub protein associated with the PI3K/AKT signaling pathway in diffuse large B-cell lymphoma based on proteomics methods., PMID:31932115
Polycyclic aromatic hydrocarbons exposure and their joint effects with age, smoking, and TCL1A variants on mosaic loss of chromosome Y among coke-oven workers., PMID:31818624
Reconstruction of rearranged T-cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T-cell prolymphocytic leukemia., PMID:31677197
The TCL1 function revisited focusing on metabolic requirements of stemness., PMID:31564197
SLAMF6 as a Regulator of Exhausted CD8+ T Cells in Cancer., PMID:31315913
Comparative transcriptome analysis of peripheral blood mononuclear cells in renal transplant recipients in everolimus- and tacrolimus-based immunosuppressive therapy., PMID:31238062
Cytoplasmic Blebs in T-Cell Prolymphocytic Leukemia., PMID:31189039
For research use only. Not for human or drug use.
