Catalog No.
YHF15701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gln205
Predicted molecular weight
24.90 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P56192
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Methionyl-tRNA synthetase, MARS1, MARS, Methionine--tRNA ligase, cytoplasmic, MetRS
Genotype-phenotype associations in microtia: a systematic review., PMID:38594752
Prediction of Prognosis in Pancreatic Cancer According to Methionyl-tRNA Synthetase 1 Expression as Determined by Immunohistochemical Staining., PMID:38001673
Comprehensive Genomic Analysis of Cemento-Ossifying Fibroma., PMID:37995913
ER proteostasis regulators cell-non-autonomously control sleep., PMID:36924492
MARS1 mutations linked to familial trigeminal neuralgia via the integrated stress response., PMID:36641423
Dissecting super-enhancer driven transcriptional dependencies reveals novel therapeutic strategies and targets for group 3 subtype medulloblastoma., PMID:36273157
Methionine supplementation for multi-organ dysfunction in MetRS-related pulmonary alveolar proteinosis., PMID:34503986
Deep phenotyping of MARS1 (interstitial lung and liver disease) and LARS1 (infantile liver failure syndrome 1) recessive multisystemic disease using Human Phenotype Ontology annotation: Overlap and differences. Case report and review of literature., PMID:34496286
Increased Mars2 expression upon microRNA-4661-5p-mediated KDM5D downregulation is correlated with malignant degree of gastric cancer cells., PMID:34273914
The Importance of Multiple Gene Analysis for Diagnosis and Differential Diagnosis in Charcot Marie Tooth Disease., PMID:34169998
Structural basis for the dynamics of human methionyl-tRNA synthetase in multi-tRNA synthetase complexes., PMID:34086935
Protein instability associated with AARS1 and MARS1 mutations causes trichothiodystrophy., PMID:33909043
Rescue of respiratory failure in pulmonary alveolar proteinosis due to pathogenic MARS1 variants., PMID:32833345
High methionyl-tRNA synthetase expression predicts poor prognosis in patients with breast cancer., PMID:32404475
New staining method using methionyl-tRNA synthetase 1 antibody for brushing cytology of bile duct cancer., PMID:31874158
The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response., PMID:31612858
A Novel Mutation in MARS in a Patient with Charcot-Marie-Tooth Disease, Axonal, Type 2U with Congenital Onset., PMID:31356216
Quantitative Lipidomics in Pulmonary Alveolar Proteinosis., PMID:31002528
Novel methionyl-tRNA synthetase gene variants/phenotypes in interstitial lung and liver disease: A case report and review of literature., PMID:30271085
Mutations in MARS identified in a specific type of pulmonary alveolar proteinosis alter methionyl-tRNA synthetase activity., PMID:29775242
Whole-exome sequencing reveals a novel missense mutation in the MARS gene related to a rare Charcot-Marie-Tooth neuropathy type 2U., PMID:29582526
Fluoromodule-based reporter/probes designed for in vivo fluorescence imaging., PMID:26348895
let-65 is cytoplasmic methionyl tRNA synthetase in C. elegans., PMID:25606464