Catalog No.
YHF03901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg70-Leu300
Predicted molecular weight
29.05 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P54619
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AMPK gamma1, AMPKg, AMPK subunit gamma-1, PRKAG1, 5'-AMP-activated protein kinase subunit gamma-1
Joint Screening and Identification of Potential Targets of Nitazoxanide by Affinity Chromatography and Label-Free Techniques., PMID:39171461
Refeeding-associated AMPKγ1 complex activity is a hallmark of health and longevity., PMID:37957359
Effect of arginine supplementation on the production of milk fat in dairy cows., PMID:35965125
Effects of dietary l-carnitine supplementation on the response to an inflammatory challenge in mid-lactating dairy cows: Hepatic mRNA abundance of genes involved in fatty acid metabolism., PMID:34253361
Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering., PMID:34033941
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy., PMID:33779513
Adiponectin enhances the bioenergetics of cardiac myocytes via an AMPK- and succinate dehydrogenase-dependent mechanism., PMID:33271223
Effects of Single-Nucleotide Polymorphisms in Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2): A Comprehensive Study., PMID:33082841
[Partial isoform-specific expression and function of AMPK in ovarian carcinoma]., PMID:32727648
The importance of the AMPK gamma 1 subunit in metformin suppression of liver glucose production., PMID:32591547
Amino acids regulate energy utilization through mammalian target of rapamycin complex 1 and adenosine monophosphate activated protein kinase pathway in porcine enterocytes., PMID:32211535
AMPK Complex Activation Promotes Sarcolemmal Repair in Dysferlinopathy., PMID:32087766
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy., PMID:31983282
AMPK variant, a candidate of novel predictor for chemotherapy in metastatic colorectal cancer: A meta-analysis using TRIBE, MAVERICC and FIRE3., PMID:30856283
DDN-AS1-miR-15a/16-TCF3 feedback loop regulates tumor progression in cervical cancer., PMID:30582201
Prolonged incubation with Metformin decreased angiogenic potential in human bone marrow mesenchymal stem cells., PMID:30372835
Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly., PMID:30232152
Visualizing AMPK Drug Binding Sites Through Crystallization of Full-Length Phosphorylated α2β1γ1 Heterotrimer., PMID:29480466
Production and Crystallization of Full-Length Human AMP-Activated Protein Kinase (α1β1γ1)., PMID:29480465
Altered intracellular signaling by imatinib increases the anti-cancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia cells., PMID:29121435
Effect of different γ-subunit isoforms on the regulation of AMPK., PMID:28302767
Discovery, synthesis, and structure-activity relationships of 20S-dammar-24-en-2α,3β,12β,20-tetrol (GP) derivatives as a new class of AMPKα2β1γ1 activators., PMID:27132866
Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms., PMID:26542978
AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell Survival., PMID:26351140
Skeletal muscle AMP-activated protein kinase γ1(H151R) overexpression enhances whole body energy homeostasis and insulin sensitivity., PMID:26306597
Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit., PMID:26276391
Rare coding variants and X-linked loci associated with age at menarche., PMID:26239645
A SNP in the 3'-untranslated region of AMPKγ1 may associate with serum ketone body and milk production of Holstein dairy cows., PMID:26226224
AMP-Activated Protein Kinase Interacts with the Peroxisome Proliferator-Activated Receptor Delta to Induce Genes Affecting Fatty Acid Oxidation in Human Macrophages., PMID:26098914
The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML., PMID:26029847
Genome-wide RNAi screen for nuclear actin reveals a network of cofilin regulators., PMID:26021350
Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer., PMID:25999130
Translational tolerance of mitochondrial genes to metabolic energy stress involves TISU and eIF1-eIF4GI cooperation in start codon selection., PMID:25738462
PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain., PMID:25695398
Frameshift mutations of PRKAG1 gene encoding an AMPK gamma subunit in colorectal cancers., PMID:25267969
Cordycepin activates AMP-activated protein kinase (AMPK) via interaction with the γ1 subunit., PMID:24286368
[Impact of AMPKgamma silencing on AMPK activation and intracellular lipids regulation]., PMID:23984516
AMPK interacts with DSCAM and plays an important role in netrin-1 induced neurite outgrowth., PMID:23479427
A role of DNA-dependent protein kinase for the activation of AMP-activated protein kinase in response to glucose deprivation., PMID:22982065
AMP-activated protein kinase regulation and biological actions in the heart., PMID:22935535
Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications., PMID:22897928
The AMPKγ1 subunit plays an essential role in erythrocyte membrane elasticity, and its genetic inactivation induces splenomegaly and anemia., PMID:20881209
Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia., PMID:20821366
AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells., PMID:19211918
Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells., PMID:19052260
AMPK activation by long chain fatty acyl analogs., PMID:18812171
Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding., PMID:18372250
AMP-activated protein kinase subunit interactions: beta1:gamma1 association requires beta1 Thr-263 and Tyr-267., PMID:18079111
Role of AMP-activated protein kinase gamma 3 genetic variability in glucose and lipid metabolism in non-diabetic whites., PMID:17701023
New indicators of beef sensory quality revealed by expression of specific genes., PMID:17547415
For research use only. Not for human or drug use.
