Catalog No.
YHF00301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr27-Phe311
Predicted molecular weight
34.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P53778
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mitogen-activated protein kinase 12, ERK6, MAPK12, Extracellular signal-regulated kinase 6, ERK-6, MAP kinase p38 gamma, SAPK3, MAPK 12, Stress-activated protein kinase 3, MAP kinase 12, Mitogen-activated protein kinase p38 gamma
CD47 expression in classic follicular lymphoma is associated with event-free survival., PMID:40374148
Therapeutic Mechanism of Zhishi Decoction Regulating P38/MAPK Signaling Pathway on Functional Constipation (FC)., PMID:39917918
Activation of P38 MAPK Signaling Cascade is Linked with Clinical Outcomes and Therapeutic Responses in Human Cancers., PMID:39865029
Identification of Novel 58-5p and SREBF1 Interaction and Effects on Apoptosis of Ovine Ovarian Granulosa Cell., PMID:39859292
Comprehensive genome-wide identification and functional characterization of mapk gene family in northern snakeheads (Channa argus)., PMID:39645216
In silico exploration of phytochemicals as inhibitors for acute myeloid leukemia by targeting LIN28A gene: A cheminformatics study., PMID:39504779
Transcriptome analysis of the cytokine storm-related genes among the subtypes of idiopathic multicentric Castleman disease., PMID:39462545
Targeting the senescence-related genes MAPK12 and FOS to alleviate osteoarthritis., PMID:39007035
A retrospective analysis of the clinicopathological features and prognostic value of MAPK12 protein expression in diffuse large B-cell lymphoma., PMID:38773060
G-quadruplex structural dynamics at MAPK12 promoter dictates transcriptional switch to determine stemness in breast cancer., PMID:38214819
Anti-Inflammatory and Analgesic Effects and Potential Targets of Shenzhu Jiedu Granule Against Novel Coronavirus Pneumonia Based on Network Pharmacology., PMID:37883768
3-deazaadenosine: A promising novel p38γ antagonist with potential as a breast cancer therapeutic agent., PMID:37481995
p38γ and p38δ modulate innate immune response by regulating MEF2D activation., PMID:37458356
Effect of prolactin on cytotoxicity and oxidative stress in ovine ovarian granulosa cells., PMID:37456891
Transcriptomic Analysis of mRNA Expression Profiles in the Microglia of Mouse Brains Infected with Rabies Viruses of Varying Virulence., PMID:37376523
Prolactin Regulates Ovine Ovarian Granulosa Cell Apoptosis by Affecting the Expression of MAPK12 Gene., PMID:37373417
MAPK11 (p38β) is a major determinant of cellular radiosensitivity by controlling ionizing radiation-associated senescence: An in vitro study., PMID:37346275
An integrative in silico and in vitro study identifies Leishmania donovani MAP kinase12 as a probable virulence factor., PMID:37329806
P38 kinase in gastrointestinal cancers., PMID:37248432
Pan-cancer analysis supports MAPK12 as a potential prognostic and immunotherapeutic target in multiple tumor types, including in THCA., PMID:36420075
Genes Whose Gain or Loss of Function Changes Type 1, 2A, 2X, or 2B Muscle Fibre Proportions in Mice-A Systematic Review., PMID:36361732
Initial activation of STAT2 induced by IAV infection is critical for innate antiviral immunity., PMID:36148221
Comparative proteomics reveals genetic mechanisms of body weight in Hu sheep and Dorper sheep., PMID:35995385
Comprehensive characterization of clonality of driver genes revealing their clinical relevance in colorectal cancer., PMID:35962343
Tyrosine Phosphorylation Profiling Revealed the Signaling Network Characteristics of CAMKK2 in Gastric Adenocarcinoma., PMID:35646067
Cardiac protection by pirfenidone after myocardial infarction: a bioinformatic analysis., PMID:35304529
The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas., PMID:34814904
Differential Expression of the Sphingolipid Pathway Is Associated with Sensitivity to the PP2A Activator FTY720 in Colorectal Cancer Cell Lines., PMID:34768523
The Role of p38γ in Cancer: From review to outlook., PMID:34671218
Machine learning identifies molecular regulators and therapeutics for targeting SARS-CoV2-induced cytokine release., PMID:34486798
A network-based approach to identify protein kinases critical for regulating srebf1 in lipid deposition causing obesity., PMID:34327622
Analysis of miRNA and mRNA reveals core interaction networks and pathways of dexamethasone-induced immunosuppression in chicken bursa of Fabricius., PMID:33711668
Transcriptomic investigation reveals toxic damage due to tilmicosin and potential resistance against tilmicosin in primary chicken myocardial cells., PMID:33248551
Additive Effects of Zinc Chloride on the Suppression of Hepatitis A Virus Replication by Interferon in Human Hepatoma Huh7 Cells., PMID:33144437
Inhibiting MAPK14 showed anti-prolactinoma effect., PMID:32894113
DNMT1 and p38γ are inversely expressed in reactive non-metastatic lymph nodes burdened with colorectal adenocarcinoma., PMID:35847731
Gene Expression Profiling of the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats with Peripheral Neuropathy., PMID:32566679
Dysregulated mitogen-activated protein kinase pathway mediated cell cycle disruption in sporadic parathyroid tumors., PMID:31535356
Revealing synergistic mechanism of multiple components in Stauntonia brachyanthera Hand.-Mazz. for gout by virtual screening and system pharmacological approach., PMID:31344517
Luteolin Targets the Toll-Like Receptor Signaling Pathway in Prevention of Hepatic and Adipocyte Fibrosis and Insulin Resistance in Diet-Induced Obese Mice., PMID:30282902
p38δ MAPK regulates aggresome biogenesis by phosphorylating SQSTM1 in response to proteasomal stress., PMID:29930081
The Dystrophin Glycoprotein Complex Regulates the Epigenetic Activation of Muscle Stem Cell Commitment., PMID:29681515
Muscle molecular adaptations to endurance exercise training are conditioned by glycogen availability: a proteomics-based analysis in the McArdle mouse model., PMID:29315579
Role of yes-associated protein 1, angiomotin, and mitogen-activated kinase kinase 1/2 in development of the bovine blastocyst., PMID:29228123
The IDO inhibitor 1-methyl tryptophan activates the aryl hydrocarbon receptor response in mesenchymal stromal cells., PMID:29190885
Crosstalk between mAChRM3 and β2AR, via acetylcholine PI3/PKC/PBEP1/Raf-1 MEK1/2/ERK1/2 pathway activation, in human bronchial epithelial cells after long-term cigarette smoke exposure., PMID:29175450
Phosphotyrosine profiling of curcumin-induced signaling., PMID:27307780
Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells., PMID:27153061
Higher levels of TIMP-1 expression are associated with a poor prognosis in triple-negative breast cancer., PMID:27130446
[Mitogen-activated protein kinase genes of Artemisia annua and their expression analysis under Cadmium stress]., PMID:28875663
For research use only. Not for human or drug use.
