Catalog No.
YHE96201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala286
Predicted molecular weight
32.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P52907
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CapZ alpha-1, CAPZA1, F-actin-capping protein subunit alpha-1
Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies., PMID:40185104
Identification of novel cytoskeleton protein involved in spermatogenic cells and sertoli cells of non-obstructive azoospermia based on microarray and bioinformatics analysis., PMID:39863862
Unveils key proteins in Xinjiang goat muscle linked to post-mortem meat quality: A TMT-based proteomic analysis., PMID:39398871
Predictive value analysis of the interaction network of Tks4 scaffold protein in colon cancer., PMID:39234565
Unveiling epithelial plasticity regulation in lung cancer: Exploring the cross-talk among Tks4 scaffold protein partners., PMID:38985526
Genome-wide characteristics and potential functions of circular RNAs from the embryo muscle development in Chengkou mountain chicken., PMID:38872802
Proteomic analysis of the developing mammalian brain links PCDH19 to the Wnt/β-catenin signalling pathway., PMID:38454084
The temporal association of CapZ with early endosomes regulates endosomal trafficking and viral entry into host cells., PMID:38273307
Efficacy of Immediate Antihypertensive Treatment in Patients With Acute Ischemic Stroke With Different Blood Pressure Genetic Variants., PMID:38174564
Polymorphism in autophagy-related genes LRP1 and CAPZA1 may promote gastric mucosal atrophy., PMID:37198664
NcRNA-regulated CAPZA1 associated with prognostic and immunological effects across lung adenocarcinoma., PMID:36686785
Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis., PMID:36643863
Identification of Key Genes and Pathways Associated with Preeclampsia by a WGCNA and an Evolutionary Approach., PMID:36421809
FAM21C Promotes Hepatocellular Carcinoma Invasion and Metastasis by Driving Actin Cytoskeleton Remodeling via Inhibiting Capping Ability of CAPZA1., PMID:35096613
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors., PMID:34796874
Corrigendum: E3 Ubiquitin Ligase UBR5 Promotes the Metastasis of Pancreatic Cancer via Destabilizing F-Actin Capping Protein CAPZA1., PMID:34046366
NUP-98 Rearrangements Led to the Identification of Candidate Biomarkers for Primary Induction Failure in Pediatric Acute Myeloid Leukemia., PMID:33925480
E3 Ubiquitin Ligase UBR5 Promotes the Metastasis of Pancreatic Cancer via Destabilizing F-Actin Capping Protein CAPZA1., PMID:33777788
CAPZA1 is low expressed in non-small cell lung cancer and contributed to tumor cell proliferation and metastasis., PMID:32914610
Actin-binding protein profilin1 promotes aggressiveness of clear-cell renal cell carcinoma cells., PMID:32883810
PIM1 accelerates prostate cancer cell motility by phosphorylating actin capping proteins., PMID:32771000
Comparative Analysis of CPI-Motif Regulation of Biochemical Functions of Actin Capping Protein., PMID:32133840
CD2AP inhibits metastasis in gastric cancer by promoting cellular adhesion and cytoskeleton assembly., PMID:31989722
MicroRNA miR-7 Regulates Secretion of Insulin-Like Peptides., PMID:31875904
ROCK inhibitor modified intraocular lens as an approach for inhibiting the proliferation and migration of lens epithelial cells and posterior capsule opacification., PMID:31389407
Annexin A3 may play an important role in ochratoxin-induced malignant transformation of human gastric epithelium cells., PMID:31276768
Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori-Infected CAPZA1-Overexpressing Cells., PMID:31146068
Transcriptome-Wide Effects of Sphingosine Kinases Knockdown in Metastatic Prostate and Breast Cancer Cells: Implications for Therapeutic Targeting., PMID:30971929
F-actin dynamics regulates mammalian organ growth and cell fate maintenance., PMID:30878582
Hypoxia induces actin cytoskeleton remodeling by regulating the binding of CAPZA1 to F-actin via PIP2 to drive EMT in hepatocellular carcinoma., PMID:30742939
CAPZA1 determines the risk of gastric carcinogenesis by inhibiting Helicobacter pylori CagA-degraded autophagy., PMID:30176157
Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus., PMID:29702546
Proteomic Analysis of Extracellular HMGB1 Identifies Binding Partners and Exposes Its Potential Role in Airway Epithelial Cell Homeostasis., PMID:28976774
Differential expression pattern of protein markers for predicting chemosensitivity of dexamethasone-based chemotherapy of B cell acute lymphoblastic leukemia., PMID:28585036
Genetic analysis of VCP and WASH complex genes in a German cohort of sporadic ALS-FTD patients., PMID:28551275
Non diaphanous formin delphilin acts as a barbed end capping protein., PMID:28527698
CAPZA1 modulates EMT by regulating actin cytoskeleton remodelling in hepatocellular carcinoma., PMID:28093067
Morphological change of skin fibroblasts induced by UV Irradiation is involved in photoaging., PMID:27539902
Preliminary Proteomic Analysis of A549 Cells Infected with Avian Influenza Virus H7N9 and Influenza A Virus H1N1., PMID:27223893
Disease causing mutations in inverted formin 2 regulate its binding to G-actin, F-actin capping protein (CapZ α-1) and profilin 2., PMID:26764407
Network-based proteomic analysis for postmenopausal osteoporosis in Caucasian females., PMID:26435169
Concurrent gene signatures for han chinese breast cancers., PMID:24098497
Prognostic value of CAPZA1 overexpression in gastric cancer., PMID:23545944
Dab1 stabilizes its interaction with Cin85 by suppressing Cin85 phosphorylation at serine 587., PMID:23178720
Identifying a role of the actin capping protein CapZ in β-adrenergic receptor signalling., PMID:22882973
Differential expression of fourteen proteins between uveal melanoma from patients who subsequently developed distant metastases versus those who did Not., PMID:22570344
Proteomics-based identification of spontaneous regression-associated proteins in neuroblastoma., PMID:22008333
Differential expression patterns of capping protein, protein phosphatase 1, and casein kinase 1 may serve as diagnostic markers for malignant melanoma., PMID:21566537
HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers., PMID:21290163
Rac1 recruits the adapter protein CMS/CD2AP to cell-cell contacts., PMID:20404345
For research use only. Not for human or drug use.
