Catalog No.
YHE88801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro854-Asn1080
Predicted molecular weight
27.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P51828
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Adenylate cyclase type VII, ADCY7, ATP pyrophosphate-lyase 7, Adenylate cyclase type 7, Adenylyl cyclase 7, KIAA0037
Eukaryotic ADCY7 catalyzes the production of c-di-AMP to activate the NLRP3 inflammasome., PMID:40419769
The ulcerative colitis risk gene adenylyl cyclase 7 restrains the T-helper 2 phenotype and Class II antigen presentation., PMID:39957491
Nuclear translocation of plasma membrane protein ADCY7 potentiates T cell-mediated antitumour immunity in HCC., PMID:39349007
Proteomics and Metabolic Characteristics of Boar Seminal Plasma Extracellular Vesicles Reveal Biomarker Candidates Related to Sperm Motility., PMID:39067049
Autoimmune hypothyroidism GWAS reveals independent autoimmune and thyroid-specific contributions and an inverse relation with cancer risk., PMID:39041034
Genetic Variants of the Beta-Adrenergic Receptor Pathways as Both Risk and Protective Factors for Retinopathy of Prematurity., PMID:38224928
Downregulation of FTO in the hippocampus is associated with mental disorders induced by fear stress during pregnancy., PMID:37506852
Identification of lipid metabolism-related biomarkers for diagnosis and molecular classification of atherosclerosis., PMID:37415143
Paternal genetic effects of cadmium exposure during pregnancy on hormone synthesis disorders in ovarian granulosa cells of offspring., PMID:37194017
Meta-Analysis Identifies BDNF and Novel Common Genes Differently Altered in Cross-Species Models of Rett Syndrome., PMID:36232428
Genome-Wide Identification and Characterization of Long Non-Coding RNAs in Longissimus dorsi Skeletal Muscle of Shandong Black Cattle and Luxi Cattle., PMID:35651943
An osteoarthritis subtype characterized by synovial lipid metabolism disorder and fibroblast-like synoviocyte dysfunction., PMID:35330945
LncRNA GAS5 promotes abdominal aortic aneurysm formation through regulating the miR-185-5p/ADCY7 axis., PMID:34974476
Bioinformatic analysis identifies potential key genes of epilepsy., PMID:34555062
RNA-seq analysis reveals the positive role of KLF5 in the differentiation of subcutaneous adipocyte in goats., PMID:34530084
CRISPR/Cas9 ADCY7 Knockout Stimulates the Insulin Secretion Pathway Leading to Excessive Insulin Secretion., PMID:34177802
Hsa_circ_0008234 facilitates proliferation of cutaneous squamous cell carcinoma through targeting miR-127-5p to regulate ADCY7., PMID:34143288
Epigenomic, Transcriptomic, and Protective Effect of Carotenoid Fucoxanthin in High Glucose-Induced Oxidative Stress in Mes13 Kidney Mesangial Cells., PMID:33448797
VLA-4 phosphorylation during tumor and immune cell migration relies on its coupling to VEGFR2 and CXCR4 by syndecan-1., PMID:31562188
Rare and common variant discovery in complex disease: the IBD case study., PMID:31363759
Chemo-resistant Gastric Cancer Associated Gene Expression Signature: Bioinformatics Analysis Based on Gene Expression Omnibus., PMID:30952707
Differentially Expressed Genes Associated with the Estrogen Receptor Pathway in Cerebral Aneurysms., PMID:30831289
Variations in maternal adenylate cyclase genes are associated with congenital Zika syndrome in a cohort from Northeast, Brazil., PMID:30222212
CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia., PMID:29938007
Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7., PMID:28067910
Aging has the opposite effect on cAMP and cGMP circadian variations in rat Leydig cells., PMID:27915366
Activation of the SDF1/CXCR4 pathway retards muscle atrophy during cancer cachexia., PMID:27212031
Analysis of genes that influence sheep follicular development by different nutrition levels during the luteal phase using expression profiling., PMID:26970339
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases., PMID:26301688
ADCY7 supports development of acute myeloid leukemia., PMID:26220344
Insulin-like growth factor 1 induces the transcription of Gap43 and Ntn1 during hair cell protection in the neonatal murine cochlea., PMID:24333914
Novel pathways in the pathobiology of human abdominal aortic aneurysms., PMID:22797469
Repeated immobilization stress disturbed steroidogenic machinery and stimulated the expression of cAMP signaling elements and adrenergic receptors in Leydig cells., PMID:22374756
Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry., PMID:22264442
PACAP interactions in the mouse brain: implications for behavioral and other disorders., PMID:22001548
Sex-specific role for adenylyl cyclase type 7 in alcohol dependence., PMID:21481845
Type 7 adenylyl cyclase-mediated hypothalamic-pituitary-adrenal axis responsiveness: influence of ethanol and sex., PMID:20363852
Human adenylyl cyclase type 7 contains polymorphic repeats in the 3' untranslated region: investigations of association with alcoholism., PMID:9034014
Localization of the gene for a novel human adenylyl cyclase (ADCY7) to chromosome 16., PMID:7860067
For research use only. Not for human or drug use.
