Catalog No.
YHE81602
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr268-Phe494
Predicted molecular weight
39.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>85% as determined by SDS-PAGE.
Accession
B6ZGS6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RAR-related orphan receptor C, RORC, NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Retinoid-related orphan receptor-gamma, RZRG, Nuclear receptor subfamily 1 group F member 3, RORG, RORgT
Experimental autoimmune encephalomyelitis impairs the immunomodulatory effects of mesenchymal stem cells on splenocyte responses., PMID:40498218
N-glycosylated LTβR increases the Th17/Treg cell ratio in liver cancer by blocking RORC ubiquitination and FOXP3 transcription., PMID:40436857
Functional targeting of ILC2s and ILC3s reveals selective roles in intestinal fibrosis and homeostasis., PMID:40434419
"What's in a name?" Clarifying the identity of RORγt+ antigen-presenting cells., PMID:40372310
Thymic Bmi-1 hampers γδT17 generation and its derived RORγt-IL-17A signaling to delay cardiac aging., PMID:40366697
Independent and temporally separated dynamics for RORγt and Foxp3 during Th17 differentiation., PMID:40356912
Specific MSI2 deletion maintains intestinal barrier integrity by down-regulating ILC3s-derived IL-17 a in mice with colitis., PMID:40279942
Particulate matter-shaped Th17 cell plasticity impairs the colonic mucus layer., PMID:40253876
Features of the Subpopulation Composition of Peripheral Blood T-Helpers in the Long-Term Period in Persons Exposed to Chronic Radiation In Utero., PMID:40216717
Alcaligenes faecalis induces intestinal T helper-17 cells by enhancing Rorc transcription through E3 ligase Trim21-mediated Fbxw7 degradation., PMID:40215968
Immunopathological Dysregulation in Acute Myeloid Leukemia: The Impact of T-bet, RORγt, and FOXP3 on Disease Dynamics., PMID:40214482
Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens., PMID:40185101
miRNA let-7f-5p-encapsulated labial gland MSC-derived EVs ameliorate experimental Sjögren's syndrome by suppressing Th17 cells via targeting RORC/IL-17A signaling axis., PMID:40114173
Regulation of IL-17A-mediated hypersensitivity by extracellular vesicles and lipid nanoparticles carrying miR-451a., PMID:40073105
LAMP2-FLOT2 interaction enhances autophagosome-lysosome fusion to protect the septic heart in response to ILC2., PMID:40066518
Study on the mechanism of Jieduquyuziyin prescription improving the condition of MRL/lpr mice by regulating T cell metabolic reprogramming through the AMPK/mTOR pathway., PMID:40043826
STING Deficiency Promotes Th17-Like Tfh to Aggravate the Experimental Autoimmune Uveitis., PMID:40042874
Paecilomyces variotii improves growth performance and modulates immunological biomarkers and gut microbiota in vaccinated Atlantic salmon pre-smolts., PMID:39988217
Interleukin-10 production by innate lymphoid cells restricts intestinal inflammation in mice., PMID:39988202
K27-linked RORγt ubiquitination by Nedd4 potentiates Th17-mediated autoimmunity., PMID:39972304
GTS-21 modulates rheumatoid arthritis Th17 and Th2 lymphocyte subset differentiation through the ɑ7nAch receptor., PMID:39812970
BACH2-driven tissue resident memory programs promote HIV-1 persistence., PMID:39763845
Modulating intestinal neuroimmune VIPergic signaling attenuates the reduction in ILC3-derived IL-22 and hepatic steatosis in MASLD., PMID:39761015
Analysis of nuclear receptor expression in head and neck cancer., PMID:39754894
RORc-expressing immune cells negatively regulate tertiary lymphoid structure formation and support their pro-tumorigenic functions., PMID:39710149
AIM2 deficiency in CD4+ T cells promotes psoriasis-like inflammation by regulating Th17-Treg axis via AIM2-IKZF2 pathway., PMID:39689661
Kaempferol Improved Rheumatoid Arthritis by Regulating the Immune Imbalance of Treg/Th17., PMID:39673582
The effector function of mucosal associated invariant T cells alters with aging and is regulated by RORγt., PMID:39669566
SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire., PMID:39656519
MIF promotes Th17 cell differentiation in rheumatoid arthritis through ATF6 signal pathway., PMID:39614150
Expression of STAT- and T-cell-related genes in women with first-line treatment of relapsing-remitting multiple sclerosis., PMID:39545481
Supplementation of Miso to a Western-Type Diet Stimulates ILC3s and Decreases Inflammation in the Small Intestine., PMID:39519576
Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis., PMID:39478228
The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner., PMID:39445009
Elevated Interleukin-21 expression is correlated with systemic sclerosis' severity in Tunisian patients., PMID:39418741
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
Intervention of inflammation associated with ankylosing spondylitis by triptolide promotes histone H3 Iys-27 trimethylation., PMID:39307916
MME and PTPRC: key renal biomarkers in lupus nephritis., PMID:39301055
Transcriptional Activity of Genes Regulating T-Helper Differentiation in the Accidentally Exposed Population of the Southern Urals., PMID:39283554
The histone methyltransferase Mixed-lineage-leukemia-1 drives T cell phenotype via Notch signaling in diabetic tissue repair., PMID:39250432
MicroRNA-142 regulates gut associated lymphoid tissues and group 3 innate lymphoid cells., PMID:39245145
Regulation of Bacteroides acidifaciens by the aryl hydrocarbon receptor in IL-22-producing immune cells has sex-dependent consequential impact on colitis., PMID:39229279
Anti-inflammatory effects of phytocannabinoids and terpenes on inflamed Tregs and Th17 cells in vitro., PMID:39208564
A majority of circadian clock genes are expressed in estrogen receptor and progesterone receptor status-dependent manner in breast cancer., PMID:39193850
Dynamic regulation of innate lymphoid cell development during ontogeny., PMID:39159846
Nobiletin promotes lipolysis of white adipose tissue in a circadian clock-dependent manner., PMID:39094217
Role of Interleukin-17 cytokine family in human T-cell lymphotropic virus type 1 (HTLV-1) infection and associated diseases., PMID:39089216
Renal IL-23-Dependent Type 3 Innate Lymphoid Cells Link Crystal-induced Intrarenal Inflammasome Activation with Kidney Fibrosis., PMID:39072698
Effects of dietary Chitosan oligosaccharides supplementation on Th17/Treg balance and gut microbiota of early weaned pigeon squabs., PMID:39067116
DeepIMAGER: Deeply Analyzing Gene Regulatory Networks from scRNA-seq Data., PMID:39062480
For research use only. Not for human or drug use.
