Catalog No.
YHE75501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro316-Gly511
Predicted molecular weight
25.41 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P50281
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MT-MMP 1, Matrix metalloproteinase-14, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP14, MTMMP1, MT1-MMP, MMP-14, MMP-X1, MT1MMP
Dysregulation of cell migration by matrix metalloproteinases in geleophysic dysplasia., PMID:40481143
Collagen Remodeling Increases After Acute Resistance Exercise in Healthy Skeletal Muscle Irrespective of Age., PMID:40454703
Genomic and transcriptomic determinants of clinical outcomes in patients with AML and DNMT3A mutations., PMID:40389402
Identification of MMP14 and MKLN1 as colorectal cancer susceptibility genes and drug-repositioning candidates from a genome-wide association study., PMID:40369569
The Effect of Curcumin on the Activity of MMP-17 and MMP-24 in Hepatocytes of Mice Exposed to Thioacetamide., PMID:40330566
IPMK depletion influences genome-wide DNA methylation., PMID:40300331
EGF-Induced Macropinocytosis Promotes NAV1-Dependent Internalization of Occludin in Keratinocytes., PMID:40266031
Circulating Exosomal Proteins as New Diagnostic Biomarkers for Colorectal Cancer (EXOSCOL01): A Pilot Case-Controlled Study Focusing on MMP14 Potential., PMID:40244893
Predicting Prognosis and Immunotherapy Response in Glioblastoma (GBM) With a 5-Gene CAF-Risk Signature., PMID:40226936
Ethyl caffeate alleviates inflammatory response and promotes recovery in septic-acute lung injury via the TNF-α/NF-κB/MMP9 Axis., PMID:40220405
Potential target within the tumor microenvironment - MT1-MMP., PMID:40196128
Soluble CD13 is a potential mediator of neutrophil-induced thrombogenic inflammation in SARS-CoV-2 infection., PMID:40168094
MMP14 from BM-MSCs facilitates progression and Ara-C resistance in acute myeloid leukemia via the JAK/STAT pathway., PMID:40121502
Regulating the expression of matrix metalloproteinases to inhibit ovarian carcinoma using isoquinoline alkaloid from Allium ascalonicum., PMID:40097575
Multi-omics analysis to uncover the molecular basis of tumor budding in head and neck squamous cell carcinoma., PMID:40082664
Claudin-11 Enhances Invasive and Metastatic Abilities of Small-Cell Lung Cancer Through MT1-MMP Activation., PMID:40079504
Expression of MMP-14 and CD147 in Gingival Tissue of Patients With and Without Diabetes Mellitus Type II., PMID:40075856
Extracellular vesicles derived from ovarian cancer cell lines discriminated by biochemical and Fourier transform infrared spectroscopy approaches., PMID:40019024
The Diverse Pathways for Cell Surface MT1-MMP Localization in Migratory Cells., PMID:39937000
Synergistic effects of matrix metalloproteinases on the degradation of collagen in abalone (Haliotis discus hannai)., PMID:39889640
RNAseq of peripheral blood mononucleated cells exposed to platelet-rich fibrin and enamel matrix derivatives., PMID:39881164
Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study., PMID:39877847
Computational network analysis of two popular skin cancers provides insights into the molecular mechanisms and reveals common therapeutic targets., PMID:39866430
Delamination of chick cephalic neural crest cells requires an MMP14-dependent downregulation of Cadherin-6B., PMID:39828493
Decoding the MMP14 integrin link: Key player in the secretome landscape., PMID:39828138
Collagen turnover during cervical remodeling involves both intracellular and extracellular collagen degradation pathways†., PMID:39823285
Matrix Metalloproteinases, Tissue Inhibitors of Metalloproteinases, and Their Ratios in Women with Polycystic Ovary Syndrome and Healthy Controls., PMID:39796177
A Versatile Skin-Derived Extracellular Matrix Hydrogel-Based Platform to Investigate the Function of a Mechanically Isolated Adipose Tissue Stromal Vascular Fraction., PMID:39766200
Metalloproteases and their inhibitors in the postpartum endometrial remodeling in dairy cows: their relationship with days to conception after parturition., PMID:39714564
Dura immunity configures leptomeningeal metastasis immunosuppression for cerebrospinal fluid barrier invasion., PMID:39710801
MiRNA-34a, miRNA-145, and miRNA-222 Expression, Matrix Metalloproteinases, TNF-α and VEGF in Patients with Different Phenotypes of Coronary Artery Disease., PMID:39684689
Mechanism of Zhengsui Wan in the Treatment of Acute Lymphoblastic Leukemia Based on Network Pharmacology and Experimental Validation., PMID:39670490
Proteomics analysis of body fluid exosomes of rheumatoid arthritis patients underwent oxhorn cupping therapy., PMID:39666600
Investigating miR-9 and miR-222 in CSF and Plasma of Neuroblastoma Patients as Metastatic and Apoptotic-Related Markers., PMID:39663279
Iron regulates MT1-MMP-mediated proMMP-2 activation and cancer cell invasion., PMID:39644603
Proteomic analysis of non-muscle invasive and muscle invasive bladder cancer highlights distinct subgroups with metabolic, matrisomal, and immune hallmarks and emphasizes importance of the stromal compartment., PMID:39582373
Effects of Minocycline on Early Wound Healing after Implant Placement: An In Vitro and Randomized Clinical Study., PMID:39563194
Network pharmacology and in vitro experiments reveal the potential therapeutic effects of Scrophularia ningpoensis Hemsl in the treatment of ameloblastoma., PMID:39551179
Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren's syndrome via suppression of the CX3CL1/CX3CR1 axis., PMID:39497829
Size exclusion chromatography based proteomic and degradomic profiling of inflammasome-activated, murine bone marrow-derived dendritic cells highlights complex retention and release of cleavage products., PMID:39378052
The mechanism of MMP14-positive tumor-associated fibroblast subsets in inhibiting PD-1 immunotherapy for esophageal cancer through exosomal tsRNA-10522., PMID:39377944
Gelatinase MMP Expression Is Correlated with Muscle Fiber Growth in Maiwa Yak Gluteus Maximus., PMID:39358579
Targeted immune cell therapy for hepatocellular carcinoma using expanded liver mononuclear cell-derived natural killer cells., PMID:39357263
Unveiling four axes ADAMTS9-AS2|MEG3/hsa-miR-150/PRKCA|MMP14 within prostate cancer through establishment of the ceRNA network., PMID:39341147
The impact of vildagliptin as an add-on therapy on matrix metalloproteinase-14 levels, liver stiffness and subclinical atherosclerosis in adolescents with type 1 diabetes and non-alcoholic steatohepatitis: A randomized controlled trial., PMID:39318059
Extracellular Vesicles Derived from Ligament Tissue Transport Interleukin-17A to Mediate Ligament-To-Bone Crosstalk in Ankylosing Spondylitis., PMID:39308181
Proteomic Heterogeneity of the Extracellular Matrix Identifies Histologic Subtype-Specific Fibroblast in Gastric Cancer., PMID:39305996
Effects of Vitamin C on the Gonad Growth, Texture Traits, Collagen Content and Synthesis Related Gene Expression of Sea Urchin (Mesocentrotus nudus)., PMID:39272349
Machine learning based identification potential feature genes for prediction of drug efficacy in nonalcoholic steatohepatitis animal model., PMID:39182075
Increased shedding of PECAM-1 associated with elevated serum MMP-14 levels as new blood indicators of dengue disease manifestation., PMID:39181201
For research use only. Not for human or drug use.
