Catalog No.
YHE64601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met51-Lys366
Predicted molecular weight
40.31 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P49354
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, FTase-alpha, FNTA, GGTase-I-alpha, CAAX farnesyltransferase subunit alpha, Ras proteins prenyltransferase subunit alpha
METTL3 promotes gastric cancer progression via modulation of FNTA-mediated KRAS/ERK signaling activation., PMID:40353746
Quantitative Proteomic Analysis Indicates That Pggt1b Deficiency Promotes Cytokine Secretion in Resiquimod-Stimulated Bone Marrow-Derived Macrophages via the NF-κB Pathway., PMID:40192076
Transcriptome analysis reveals modulations in glycosylation profiles of the mucosal barrier and their potential interaction with gut microbiota in weaned piglets., PMID:39990197
Evaluating the In Situ Effects of Whole Protein Coronas on the Biosensing of Antibody-Immobilized Nanoparticles Using Two-Color Fluorescence Nanoparticle Tracking Analysis., PMID:39940196
Analysis of small extracellular vesicles from dried blood spots., PMID:39931421
Harnessing the Power of MicroRNA Cargoes in Small Extracellular Vesicles Released from Fresh-Frozen Human Brain Sections., PMID:39584691
Differential responses of selectively bred mussels (Perna canaliculus) to heat stress-survival, immunology, gene expression and microbiome diversity., PMID:38425477
Prenyltransferase gene expression reveals an essential role of prenylation for the inflammatory response in human gingival fibroblasts., PMID:37432945
Prenylated PALM2 Promotes the Migration of Esophageal Squamous Cell Carcinoma Cells Through Activating Ezrin., PMID:37328063
DNMG: Deep molecular generative model by fusion of 3D information for de novo drug design., PMID:36764588
Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association., PMID:33257571
Usefulness of bile as a biomarker via ferroptosis and cysteine prenylation in cholangiocarcinoma; role of diagnosis and differentiation from benign biliary disease., PMID:32891325
Differential fluorescence nanoparticle tracking analysis for enumeration of the extracellular vesicle content in mixed particulate solutions., PMID:32081745
Protein expression of prenyltransferase subunits in postmortem schizophrenia dorsolateral prefrontal cortex., PMID:32066669
Androgen receptor-regulated circFNTA activates KRAS signaling to promote bladder cancer invasion., PMID:32052578
Functional Regulation of an Oxidative Stress Mediator, Rac1, in Diabetic Retinopathy., PMID:31300985
Assessment of Protein Prenylation Pathway in Multiple Sclerosis Patients., PMID:29574663
Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fraction., PMID:24356578
Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretion., PMID:23322769
A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease., PMID:23209424
Ki-67 grading of nonfunctioning pancreatic neuroendocrine tumors on histologic samples obtained by EUS-guided fine-needle tissue acquisition: a prospective study., PMID:22898415
Constitutional trisomy 8p11.21-q11.21 mosaicism: a germline alteration predisposing to myeloid leukaemia., PMID:21848520
High prevalence of laminopathies among patients with metabolic syndrome., PMID:21724554
Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study., PMID:19841875
Contribution of energy restriction and macronutrient composition to changes in adipose tissue gene expression during dietary weight-loss programs in obese women., PMID:18782868
The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling., PMID:8599089
cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences., PMID:8276393
For research use only. Not for human or drug use.
