Catalog No.
YHE53601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Phe136
Predicted molecular weight
17.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P47929
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Galectin-7, PIG1, p53-induced gene 1 protein, HKL-14, PI7, Gal-7, LGALS7
Clinical Effectiveness, Clinical Stability, and Effects on Serum Galectin-7 Levels of Dupilumab and JAK Inhibitors in Moderate-to-Severe Atopic Dermatitis: A Real-World, Single-Center Analysis., PMID:40428884
Melanoma Proteomics Unveiled: Harmonizing Diverse Data Sets for Biomarker Discovery and Clinical Insights via MEL-PLOT., PMID:40322912
Development of Galectin-7-Specific Nanobodies: Implications for Immunotherapy and Molecular Imaging in Cancer., PMID:40208951
Targeting the Galectin-7/TRPM2/Zn2+/DRP-1 Signaling Pathway: A Potential Therapeutic Intervention in the Pathogenesis of SJS/TEN., PMID:40042066
Expression and prongostic impact of galectin-7 in human lung cancer., PMID:39465762
ANGPTL4 plays a paradoxical role in gastric cancer through the LGALS7 and Hedgehog pathways., PMID:39369030
Galectin-7 Expression in the Placentas of Women with Gestational Diabetes Mellitus., PMID:39337670
[Levels of Galectin-7 in serum and sputum in children with asthma]., PMID:38763876
Galectin 7 leads to a relative reduction in CD4+ T cells, mediated by PD-1., PMID:38503797
A novel multi-ancestry proteome-wide Mendelian randomization study implicates extracellular proteins, tubular cells, and fibroblasts in estimated glomerular filtration rate regulation., PMID:37774922
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs., PMID:36693903
Identification of Galectin-7 as a crucial metastatic enhancer of squamous cell carcinoma associated with immunosuppression., PMID:36335283
Human Galectin-7 Gene LGALS7 Promoter Sequence Polymorphisms and Risk of Spontaneous Intracerebral Hemorrhage: A Prospective Study., PMID:35401111
Functions and Inhibition of Galectin-7, an Emerging Target in Cellular Pathophysiology., PMID:34827718
Identification of a new regulation pathway of EGFR and E-cadherin dynamics., PMID:34811416
Galectin-1 induces gene and protein expression related to maternal-conceptus immune tolerance in bovine endometrium†., PMID:34792096
Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7., PMID:34673030
Quantitative proteomics identifies biomarkers to distinguish pulmonary from head and neck squamous cell carcinomas by immunohistochemistry., PMID:34647699
CCCTC-binding factor transcriptionally regulates Galectin-7 and activates the JNK/STAT3 axis to aggravate bronchial epithelial cell injury., PMID:34643340
Paeoniflorin inhibits proliferation and migration of psoriatic keratinocytes via the lncRNA NEAT1/miR-3194-5p/Galectin-7 axis., PMID:34459454
Interaction of Gal-7 with HMGCS1 In Vitro May Facilitate Cholesterol Deposition in Cultured Keratinocytes., PMID:34454908
Enhanced galectin-7 expression favors wound healing., PMID:34318956
Towards a Better Understanding of the Relationships between Galectin-7, p53 and MMP-9 during Cancer Progression., PMID:34198494
Imitating evolution's tinkering by protein engineering reveals extension of human galectin-7 activity., PMID:34152508
Degraded Arabinogalactans and Their Binding Properties to Cancer-Associated Human Galectins., PMID:33920014
First Evidence for a Role of Siglec-8 in Breast Cancer., PMID:33670444
Autophagy Receptor Tollip Facilitates Bacterial Autophagy by Recruiting Galectin-7 in Response to Group A Streptococcus Infection., PMID:33425778
Ultrasound‑targeted microbubble destruction‑mediated Galectin‑7‑siRNA promotes the homing of bone marrow mesenchymal stem cells to alleviate acute myocardial infarction in rats., PMID:33416139
Binding of a Soluble meso-Tetraarylporphyrin to Human Galectin-7 Induces Oligomerization and Modulates Its Pro-Apoptotic Activity., PMID:33231438
Galectins-1, -3, -7, -8 and -9 as prognostic markers for survival in epithelial ovarian cancer: A systematic review and meta-analysis., PMID:33156523
Galectin-7 downregulation in lesional keratinocytes contributes to enhanced IL-17A signaling and skin pathology in psoriasis., PMID:33055419
Neoglycolipids as Glycosphingolipid Surrogates for Protein Binding Studies Using Nanodiscs and Native Mass Spectrometry., PMID:32940034
Proteomic analysis shows that the main constituent of subepidermal localised cutaneous amyloidosis is not galectin-7., PMID:32867548
Galectin-7 Impairs Placentation and Causes Preeclampsia Features in Mice., PMID:32862708
Pro4 prolyl peptide bond isomerization in human galectin-7 modulates the monomer-dimer equilibrum to affect function., PMID:32766716
Er:YAG laser promotes proliferation and wound healing capacity of human periodontal ligament fibroblasts through Galectin-7 induction., PMID:32540310
Protective role of Galectin-7 for skin barrier impairment in atopic dermatitis., PMID:32474952
The plasma peptides of breast versus ovarian cancer., PMID:31889940
Natural and synthetic pathogen associated molecular patterns modulate galectin expression in cow blood., PMID:31602302
Therapeutic effects of hydro-alcoholic extract of Achillea wilhelmsii C. Koch on indomethacin-induced gastric ulcer in rats: a proteomic and metabolomic approach., PMID:31391093
Lichen Sclerosus: An autoimmunopathogenic and genomic enigma with emerging genetic and immune targets., PMID:31337973
Galectin-7 as a potential biomarker of Stevens-Johnson syndrome/toxic epidermal necrolysis: identification by targeted proteomics using causative drug-exposed peripheral blood cells., PMID:31100551
Quantitative proteomic characterization of lung tissue in idiopathic pulmonary fibrosis., PMID:30774578
A potential contribution of decreased galectin-7 expression in stratified epithelia to the development of cutaneous and oesophageal manifestations in systemic sclerosis., PMID:30739341
Silencing of Gal-7 inhibits TGF-β1-induced apoptosis of human airway epithelial cells through JNK signaling pathway., PMID:30594507
Differential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Metastases., PMID:30228356
HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling., PMID:30083263
Serum Galectin 7 is Not Useful to Predict Abortion in the First Trimester., PMID:29693486
Immunohistochemical Analysis of Galectins-1, -3, and -7 in Periapical Granulomas, Radicular Cysts, and Residual Radicular Cysts., PMID:29510866
Clinical significance of neutrophil gelatinase-associated lipocalin and galectin-7 in tape-stripped stratum corneum of acne vulgaris., PMID:29473202
For research use only. Not for human or drug use.
