Catalog No.
YHE45201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-His353
Predicted molecular weight
41.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P45844
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP-binding cassette transporter 8, ABC8, ATP-binding cassette sub-family G member 1, ABCG1, WHT1, White protein homolog
PCSK9 inhibition mitigates vulnerable plaque formation induced by hyperhomocysteinemia through regulating lipid metabolism and inflammation., PMID:40480522
Allicin induced vasorelaxation via endothelium-dependent and endothelium-independent mechanisms., PMID:40420838
The macrophage sterol transport protein ORP2 promotes cholesterol efflux and prevents foam cell formation and atherosclerosis., PMID:40349776
Pro-Atherosclerotic Effects of Osteopontin Is Contributed to Promoting Foam Cell Formation Derived From VSMCs by Inhibiting Cholesterol Efflux., PMID:40332823
Amelioration of atherosclerotic complications and dyslipidemia by verbascoside-enriched fraction of Clerodendrum glandulosum leaves targeting LDL-R and LXR-mediated reverse cholesterol transport., PMID:40256711
Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case-Control Study., PMID:40225014
Imeglimin Inhibits Macrophage Foam Cell Formation and Atherosclerosis in Streptozotocin-Induced Diabetic ApoE-Deficient Mice., PMID:40214426
Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia., PMID:40211340
Ethanol extract of Portulaca oleracea L. mitigates atherosclerosis through modulation of cholesterol efflux and uptake pathways., PMID:40176886
Cholesterol Accumulation Enhances Cigarette Smoke-Induced Airway Epithelial Inflammation., PMID:40008109
Associations of excessive gestational weight gain with changes in components of maternal reverse cholesterol transport and neonatal outcomes., PMID:39962221
Vitamin D reduces VSMC foam cell formation and protects against AS progression., PMID:39960435
Interleukin-4 ameliorates macrophage lipid stress through promoting cholesterol efflux and lipid homeostasis., PMID:39954486
Soyasapogenol C: A novel liver X receptor α Agonist that mitigates cholesterol accumulation in diabetic kidney disease., PMID:39946984
SMC Abca1 and Abcg1 Deficiency Enhances Urinary Bladder Distension but Not Atherosclerosis., PMID:39931819
Systems Biology Approach to Unraveling Transcriptomic Mechanisms of Ganfule Capsules in Ameliorating Nonalcoholic Fatty Liver Disease., PMID:39917919
A Structural Bioinformatics-Guided Study of Adenosine Triphosphate-Binding Cassette (ABC) Transporters and Their Substrates., PMID:39852261
Longitudinal association between DNA methylation and type 2 diabetes: findings from the KORA F4/FF4 study., PMID:39827095
[Mechanism of chrysophanol in inhibiting ox-LDL-induced macrophage foaminess through NF-κB/HMGB1-PI3K/Akt/mTOR pathway]., PMID:39805790
USP18 Promotes Cholesterol Efflux and Mitigates Atherosclerosis by Deubiquitinating ABCG1., PMID:39804798
Floralozone attenuates atherosclerotic vascular injury by regulating AMPKα/SREBP-1c pathway and down-regulating miR-33-5p., PMID:39775070
DNA methylation levels may contribute to severe hypertriglyceridemia in multifactorial chylomicronemia syndrome., PMID:39756670
Fatty acids from cheese stimulate cholesterol efflux by ATP-binding cassette transporters., PMID:39725457
Indole-3-Carboxaldehyde Inhibits Inflammatory Response and Lipid Accumulation in Macrophages Through the miR-1271-5p/HDAC9 Pathway., PMID:39698913
Functional omics of ORP7 in primary endothelial cells., PMID:39695567
Peripheral blood ABCG1 gene DNA methylation: mediating the relationship between dietary intake of methyl donor nutrients and stroke risk., PMID:39675233
ABCG1 orchestrates adipose tissue macrophage plasticity and insulin resistance in obesity by rewiring saturated fatty acid pools., PMID:39661702
FABP4 Inhibitor Alleviates Lipopolysaccharide-Induced HUVEC Injury by Inactivating NF-κB and Activating PPARγ., PMID:39617505
The association of ABC proteins with multidrug resistance in cancer., PMID:39571941
MicroRNA 223 Enhances ABCA1 Protein Stability and Supports Efflux in Cholesterol-Burdened Macrophages., PMID:39541001
Link Between Metabolic Syndrome, Blood Lipid Markers, Dietary Lipids, and Survival in Women with Early-Stage Breast Cancer., PMID:39519412
Chitosan oligosaccharides: A potential therapeutic agent for inhibiting foam cell formation in atherosclerosis., PMID:39491693
Exploration of anti-atherosclerotic activity of 1,8-cineole through network pharmacology, molecular docking, and in vivo efficacy studies in high-fat-diet-induced atherosclerosis in hamsters., PMID:39463214
Plasma from type 1 diabetes patients promotes pro-atherogenic cholesterol transport in human macrophages., PMID:39417428
Targeted delivery of rosuvastatin enhances treatment of hyperhomocysteinemia-induced atherosclerosis using macrophage membrane-coated nanoparticles., PMID:39345941
Longitudinal association of peripheral blood DNA methylation with liver fat content: distinguishing between predictors and biomarkers., PMID:39334355
The Lian-Dou-Qing-Mai Formula activates the PPARγ-LXRα-ABCA1/ABCG1 pathway by regulating IL-10, leading to the promotion of cholesterol efflux and a reduction in atherosclerotic plaques., PMID:39315497
IFIT2 mediates iron retention and cholesterol efflux in atherosclerosis., PMID:39276454
HDL cholesterol efflux capacity and cholesterol loading capacity in long-term fasting: Evidence from a prospective, single-arm interventional study in healthy individuals., PMID:39180960
Cholesterol Accumulation Promotes Photoreceptor Senescence and Retinal Degeneration., PMID:39167399
Letter to the Editor From Hoekstra: "Adrenal Abcg1 Controls Cholesterol Flux and Steroidogenesis"., PMID:39104222
Mutagenesis on a complex mouse genetic background by site-specific nucleases., PMID:39088185
The Expression of Genes Related to Reverse Cholesterol Transport and Leptin Receptor Pathways in Peripheral Blood Mononuclear Cells Are Decreased in Morbid Obesity and Related to Liver Function., PMID:39062791
Response to Letter to the Editor From Hoekstra: "Adrenal Abcg1 Controls Cholesterol Flux and Steroidogenesis"., PMID:39041176
Increased risk of severe neonatal opioid withdrawal syndrome in pregnancies with low placental ABCB1 DNA methylation., PMID:39033231
Rice bran active peptide (RBAP) inhibited macrophage differentiation to foam cell and atherosclerosis in mice via regulating cholesterol efflux., PMID:39032281
Intersecting Blood Cytokines With Cholesterol Parameters to Profile Patients With Advanced Solid Tumors Receiving Immune Checkpoint Inhibitors., PMID:38989743
Gene-specific transcriptional activation by the Aspergillus fumigatus AtrR factor requires a conserved C-terminal domain., PMID:38975761
DHA dietary intervention caused different hippocampal lipid and protein profile in ApoE-/- and C57BL/6J mice., PMID:38971007
LncRNA DANCR promotes macrophage lipid accumulation through modulation of membrane cholesterol transporters., PMID:38968577
For research use only. Not for human or drug use.
