Catalog No.
YHE43301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-His491
Predicted molecular weight
57.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43490
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NAMPT, Pre-B-cell colony-enhancing factor 1, NAmPRTase, Pre-B cell-enhancing factor, Nicotinamide phosphoribosyltransferase, Visfatin, PBEF, PBEF1, Nampt
The NAMPT enzyme employs a switch that directly senses AMP/ATP and regulates cellular responses to energy stress., PMID:40505662
Visual Diagnostic Strategy for Assessing the Impact of Aerobic Glycolytic Processes on Tumor Growth and Therapy., PMID:40476754
NAD+ Metabolism Maintains the Homeostasis of Decidual Macrophages in Early Pregnancy., PMID:40471104
NAD+ biosynthesis and mitochondrial repair in acute kidney injury via ultrasound-responsive thylakoid-integrating liposomes., PMID:40461655
Novel Carbamate-Based o-aminobenzamide Derivatives as Potent Antigastric Carcinoma Agents via Disrupting NAD+ Salvage Synthesis., PMID:40448666
Adipokines as Potential Biomarkers in Pregnancy: A Naturalistic Study of Adipokines in Pregnant Women and Newborns., PMID:40427500
Predictive modeling of ARDS mortality integrating biomarker/cytokine, clinical and metabolomic data., PMID:40419238
[Study of the role of biomarkers in determining the course of non-alcoholic fatty liver disease in children with obesity]., PMID:40418137
Tetramethylpyrazine: A fermented alcohol product that mitigates alcoholic liver disease in mice., PMID:40412569
Examination of hemorheological and exerkine concentrations at four-week whole body vibration exercise in obese women: A pilot study., PMID:40392016
Anti-CHI3L1 antibody suppresses colon cancer growth through downregulation of VEGFA and NAMPT expression., PMID:40377878
Identification and Exploration of Pyroptosis-Related Genes in Macrophage Cells Reveal Necrotizing Enterocolitis Heterogeneity Through Single-Cell and Bulk-Sequencing., PMID:40362275
NAMPT-mediated deacetylation of HCLS1 protein promotes clonogenic growth of pediatric CML cells., PMID:40349748
Inhibition of NAMPT as a therapeutic strategy to suppress tumor growth in lymphangioleiomyomatosis., PMID:40348345
Mechanisms of resistance to NAMPT inhibitors in cancer., PMID:40342733
Astragalus Polysaccharide Alleviates Cognitive Decline in D-Galactose-Induced Aging., PMID:40335326
The effect of visfatin on the transcriptomic profile of porcine anterior pituitary cells during periimplantation period., PMID:40328795
NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity., PMID:40320990
NAMPT regulates mitochondria and oxidative stress level for mouse early embryo development., PMID:40320561
NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging., PMID:40311622
Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT., PMID:40308001
NAMPT Impairs Vascular Permeability in Periodontitis by Influencing FASN-mediated Lipogenesis., PMID:40303304
High Serum Levels of Irisin, Visfatin and Adiponectin as Potential Independent Risk Factors for Diabetic Nephropathy Progression in Patients With Type 2 Diabetes Mellitus., PMID:40294981
Discovery of Potent PDEδ/NAMPT Dual Inhibitors: Preclinical Evaluation in KRAS Mutant Pancreatic Cancer Cells., PMID:40289347
The Role of Visfatin in Gastric and Esophageal Cancer: From Biomarker to Therapeutic Target., PMID:40282553
Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer., PMID:40280967
Decreased plasma visfatin concentrations in pediatric aneurysmal bone cyst: a pilot study., PMID:40239975
Small Extracellular Vesicle-Derived Nicotinamide Phosphoribosyltransferase (NAMPT) Induces Acyl-Coenzyme A Synthetase SLC27A4-Mediated Glycolysis to Promote Hepatocellular Carcinoma., PMID:40237223
Identification of Ferroptosis-Associated Genes in Primary Open-Angle Glaucoma through Bioinformatics Analysis., PMID:40228223
Circadian Regulation of Vitamin D Target Genes Reveals a Network Shaped by Individual Responsiveness., PMID:40218962
NAMPT Modulates Gemcitabine Resistance in Pancreatic Cancer via the p53 Signaling Pathway., PMID:40209023
Visfatin (rs3801266) and Adiponutrin (rs738409) gene single nucleotide polymorphisms in patients with Hashimoto's thyroiditis., PMID:40205282
Serum visfatin characteristic peak screening coronary heart disease study based on Raman spectroscopy., PMID:40193654
Tangeretin alleviates myocardial ischemia-reperfusion injury by inhibiting ferroptosis via targeting nicotinamide phosphoribosyltransferase (NAMPT)., PMID:40185323
Decreased mitochondrial NAD+ in WRN deficient cells links to dysfunctional proliferation., PMID:40179319
De novo NAD+ synthesis is ineffective for NAD+ supply in axenically cultured Caenorhabditis elegans., PMID:40175694
Analysis of Nicotine Toxicity and Mechanisms of Senescence in Nucleus Pulposus Cells Using Network Toxicology and Molecular Docking Technique., PMID:40171441
Relationship of visfatin with obesity and osteoporosis in patients with inflammatory bowel disease: a narrative review., PMID:40170859
Halting hepatocellular carcinoma: Identifying intercellular crosstalk in HBV-driven disease., PMID:40163359
Preventing neuropathy and improving anti-cancer chemotherapy with a carbazole-based compound., PMID:40161707
NEDD4 E3 ligase-catalyzed NAMPT ubiquitination and autophagy activation are essential for pyroptosis-independent NAMPT secretion in human monocytes., PMID:40159488
Enhancing nicotinamide mononucleotide production in Escherichia coli through systematic metabolic engineering., PMID:40157454
A Pilot Study: Maternal Undernutrition Programs Energy Metabolism and Alters Metabolic Profile and Morphological Characteristics of Skeletal Muscle in Postnatal Beef Cattle., PMID:40137173
Uncovering Hippo pathway-related biomarkers in acute myocardial infarction via scRNA-seq binding transcriptomics., PMID:40133574
eNAMPT Is a Novel DAMP and Therapeutic Target in Human and Murine Pulmonary Fibrosis., PMID:40126452
Nicotinamide metabolism reprogramming drives reversible senescence of glioblastoma cells., PMID:40116940
Suppression of ATP-dependent (S)-NAD(P)H-hydrate dehydratase expression inhibits adipocyte differentiation of 3T3-L1 preadipocytes by increasing excessive accumulation of NADHX., PMID:40113573
Effects of quercetin and derivatives on NAMPT/Sirtuin-1 metabolic pathway in neuronal cells: an approach to mitigate chemotherapy-induced cognitive impairment., PMID:40085284
eNAMPT/Ac-STAT3/DIRAS2 Axis Promotes Development and Cancer Stemness in Triple-Negative Breast Cancer by Enhancing Cytokine Crosstalk Between Tumor-Associated Macrophages and Cancer Cells., PMID:40083697
Targeting NAD + biosynthesis suppresses TGF-β1/Smads/RAB26 axis and potentiates cisplatin cytotoxicity in non-small cell lung cancer brain metastasis., PMID:40069888
For research use only. Not for human or drug use.
