Catalog No.
YHE40701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala42-Ala271
Predicted molecular weight
28.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43251
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Biotinidase, Biotinase, BTD
RBPJ/PAF1 Signaling Axis Promotes Cloning Expansion in Paroxysmal Nocturnal Hemoglobinuria Through NOTCH Signaling., PMID:40501337
Beyond the homozygous paradigm: symptomatic partial biotinidase deficiency in a heterozygous child-first case report from Nepal., PMID:40468249
Plasma Circulating Proteins and Intracranial Aneurysm Susceptibility: A Proteome-Wide Mendelian Randomization Analysis., PMID:40294794
A Large-Scale Retrospective Study of Serum Des-Gamma-Carboxy Prothrombin as a Diagnostic Marker of HCC: Effect of Liver Function on Specificity., PMID:40230049
Characterizing Sarcoidosis Patients With Obstructive Respiratory Physiology., PMID:40220990
Genetic analyses of Culicoides peregrinus (Diptera: Ceratopogonidae) reveal population differentiation in southern India a hotspot of bluetongue disease outbreaks and lack of gene flow across its range., PMID:40152496
Omics data integration analysis identified new biological insights into chronic antibody-mediated rejection (CAMR)., PMID:39979925
Serological Survey of Leptospira spp. in Livestock and Rodents from Different Settlements in the Kilombero Wetland, Tanzania., PMID:39770319
Multisubstrate-based system: a kinetic mechanism study of catechol-O-methyltransferase., PMID:39726140
A single-base deletion in exon 2 of Hd1 delineates monogenic recessive photoperiod insensitivity in aromatic Joha rice: a novel allele for seasonal adaptability., PMID:39614365
Identification of the mutations in BTD gene in Iranian patients with biotinidase deficiency and evaluating their genotype-phenotype correlations., PMID:39461572
Modulation of intramolecular freedom for tuning fluorescence imaging and photooxidation of amyloid-β aggregates., PMID:39295492
An activity-based sensing fluorogenic probe for monitoring O-methyltransferase in plants., PMID:39233529
Biallelic loss-of-function variations in BTD cause profound biotinidase deficiency in an Indian patient., PMID:39120718
Novel Pan-Coronavirus 3CL Protease Inhibitor MK-7845: Biological and Pharmacological Profiling., PMID:39066320
Flaring Inflammation and ER Stress by an Organelle-Specific Fluorescent Cage., PMID:38848965
Butterfly eyespots exhibit unique patterns of open chromatin., PMID:38778811
A bimodal time-gated luminescence-magnetic resonance imaging nanoprobe based on a europium(III) complex anchored on BSA-coated MnO2 nanosheets for highly selective detection of H2O2., PMID:38767669
Identification of Novel and Recurrent Variants in BTD, GBE1, AGL and ASL Genes in Families with Metabolic Disorders in Saudi Arabia., PMID:38592052
A candidate panel of eight urinary proteins shows potential of early diagnosis and risk assessment for diabetic kidney disease in type 1 diabetes., PMID:38574989
Proteomic characteristics of the treatment trajectory of patients with COVID-19., PMID:38532129
Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains., PMID:38473830
Safety and Efficacy of Apitegromab in Patients With Spinal Muscular Atrophy Types 2 and 3: The Phase 2 TOPAZ Study., PMID:38330285
Challenges and opportunities in spinal muscular atrophy therapeutics., PMID:38267192
Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators., PMID:38101041
Determination of Carrier Frequency of Actionable Pathogenic Variants in Autosomal Recessive Genetic Diseases in the Turkish Cypriot Population., PMID:37895316
Perioperative Factors Associated With Postoperative Delirium in Patients Undergoing Noncardiac Surgery: An Individual Patient Data Meta-Analysis., PMID:37819663
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response., PMID:37735622
BTD: A TRPC5 activator ameliorates mechanical allodynia in diabetic peripheral neuropathic rats by modulating TRPC5-CAMKII-ERK pathway., PMID:37673218
Towards the Definition of the Molecular Hallmarks of Idiopathic Membranous Nephropathy in Serum Proteome: A DIA-PASEF Approach., PMID:37511514
Identifying Biomarkers of Spinal Muscular Atrophy for Further Development., PMID:37458045
Development and validation of an international preoperative risk assessment model for postoperative delirium., PMID:37290122
A novel benzothiazole derivative induces apoptosis via the mitochondrial intrinsic pathway producing antitumor activity in colorectal cancer., PMID:37288115
A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors., PMID:37172578
Identification and characterization of the largest deletion in the PCCA gene causing severe acute early-onset form of propionic acidemia., PMID:37131081
Transient Receptor Potential Canonical 5 (TRPC5) Channels Activator, BTD [N-{3-(adamantan-2-yloxy)-propyl}-3-(6-methyl-1,1-dioxo-2H-1λ6,2,4- benzothiadiazin-3-yl)-propanamide)] Ameliorates Diabetic Cardiac Autonomic Neuropathy in Rats., PMID:37013433
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response., PMID:36865103
Payload-Binding Fab Fragments Increase the Therapeutic Index of MMAE Antibody-Drug Conjugates., PMID:36723609
Comprehensive profiling of antibody responses to the human anellome using programmable phage display., PMID:36543141
Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock., PMID:36459524
Disease Burden of Spinal Muscular Atrophy: A Comparative Cohort Study Using Insurance Claims Data in the USA., PMID:36314213
Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis., PMID:35033099
Rapid Biosensing Method for Detecting Protein-DNA Interactions., PMID:34979074
Bis-triazolylchalcogenium-Functionalized Benzothiadiazole Derivatives as Light-up Sensors for DNA and BSA., PMID:34843245
Construction of a Highly Sensitive Thiol-Reactive AIEgen-Peptide Conjugate for Monitoring Protein Unfolding and Aggregation in Cells., PMID:34655462
Fluorescent Benzothiadiazole Derivatives as Fluorescence Imaging Dyes: A Decade of New Generation Probes., PMID:34643974
Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Prostate Cancer: The Primary Results of the PRONOUNCE Randomized Trial., PMID:34459214
Risdiplam-Treated Infants with Type 1 Spinal Muscular Atrophy versus Historical Controls., PMID:34320287